Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

omp10 from Brucella melitensis bv. 1 str. 16M

Victor ID 1326
Gene Name omp10 from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1197788
NCBI Protein GI 17988361
Locus Tag BMEII0017
Protein Accession NP_540994.1
Other Database IDs UniProtKB-ID: D0B5S9_BRUME
UniRef100: UniRef100_P0A3P0
UniRef90: UniRef90_P0A3P0
UniRef50: UniRef50_P0A3P0
UniParc: UPI0000058300
EMBL: GG703779
EMBL-CDS: EEW86971.1
RefSeq_NT: NC_003318.1
OMA: NMTSLVR
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 15807
Gene Ending Position 16187
Gene Strand (Orientation) +
Protein Name OUTER MEMBRANE LIPOPROTEIN
DNA Sequence
>gi|17988344:15807-16187 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
CATGAAACGCTTCCGCATCGTTGCCCCCCTCGCACTCATGTCGCTTGCGCTGGCTGCTTGCGAAACAACA
GGCCCGGGCAGCGGCAATGCCCCGATCATAGCCCATACCCCTGCCGGCATAGAAGGAAGCTGGGTCGATC
CGAATGGCATCGCTTCCTCATTCAATGGCGGCATCTTTGAAACCCGCACCACCGACACCAACGAAAAGCT
GGCGGAGGGCAACTATCTCTACCTGTCGCCGCAACTCGTTGAAATCAACATGCGGTCCATCGTGCGCGGC
ACCACCTCGAAGGTAAATTGCGCACTGGTTTCGCCGACGCAACTTAACTGCACCTCCTCGGCCGGTTCGC
GCTTCTCGCTCACCCGCCGCAACGCCGGCTG
Protein Sequence
>gi|17988361|ref|NP_540994.1| outer membrane lipoprotein [Brucella melitensis bv. 1 str. 16M] MKRFRIVAPLALMSLALAACETTGPGSGNAPIIAHTPAGIEGSWVDPNGIASSFNGGIFETRTTDTNEKLAEGNYLYLSPQLVEINMRSIVRGTTSKVNCALVSPTQLNCTSSAGSRFSLTRRNAG
Molecule Role Virulence factor
Molecule Role Annotation SUBCELLULAR LOCATION: Outer membrane; lipid-anchor(UniProt: P0A3N9).

MISCELLANEOUS: Elicits an immune response in B.melitensis-infected sheep but not in B.abortus-infected cattle(UniProt: P0A3N9).

SIMILARITY: Belongs to the rhizobiaceae omp10 lipoprotein family(UniProt: P0A3N9).

MUTATION: Omp10 is an immunoreactive outer membrane lipoprotein. The omp10 mutant was dramatically attenuated for survival in mice and was defective for growth in minimal medium but was not impaired in intracellular growth in vitro, nor does it display clear modification of the outer membrane properties (Tibor et al., 2002).
References
Tibor et al., 2002: Tibor A, Wansard V, Bielartz V, Delrue RM, Danese I, Michel P, Walravens K, Godfroid J, Letesson JJ. Effect of omp10 or omp19 deletion on Brucella abortus outer membrane properties and virulence in mice. Infection and immunity. 2002; 70(10); 5540-5546. [PubMed: 12228280].