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hspR from Mycobacterium tuberculosis H37Rv

Victor ID 130
Gene Name hspR from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885929
NCBI Protein GI 15607494
Locus Tag Rv0353
Protein Accession NP_214867.1
Other Database IDs UniProtKB-ID: O06302_MYCTU
UniRef100: UniRef100_A5TZ80
UniRef90: UniRef90_A5TZ80
UniRef50: UniRef50_A0LWT0
UniParc: UPI00000D0FD9
EMBL: AE000516
EMBL: BX842573
EMBL-CDS: AAK44590.1
EMBL-CDS: CAB08585.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
HSSP: P71039
EnsemblGenome: EBMYCG00000001943.
EnsemblGenome_TRS: EBMYCT00000001945
EnsemblGenome_PRO: EBMYCP00000001945
EnsemblGenome: EBMYCG00000072501.
EnsemblGenome_TRS: EBMYCT00000072506
EnsemblGenome_PRO: EBMYCP00000070565
GenomeReviews: AE000516
Taxonomy ID 83332
Gene Starting Position 423638
Gene Ending Position 424018
Gene Strand (Orientation) +
Protein Name PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR (MERR FAMILY)
DNA Sequence 
>gi|57116681:423638-424018 Mycobacterium tuberculosis H37Rv, complete genome
GATGGCGAAGAACCCAAAGGACGGGGAATCCCGGACGTTTTTGATCTCGGTAGCCGCCGAGCTAGCCGGC
ATGCATGCACAGACCCTGCGTACCTACGATCGTCTTGGGTTGGTCAGCCCGCGGCGCACCTCCGGTGGCG
GGCGCCGCTATTCCCTGCATGACGTCGAGTTGCTGCGCCAGGTGCAGCACCTCTCGCAGGACGAGGGGGT
CAACTTGGCCGGCATCAAGCGCATTATTGAACTGACCAGTCAGGTCGAGGCGCTGCAGTCCAGGTTGCAA
GAGATGGCTGAGGAGTTGGCGGTGTTGCGTGCCAACCAGCGCCGCGAGGTCGCGGTGGTGCCGAAGAGCA
CCGCCCTGGTCGTCTGGAAACCGCGCCGGTG
Protein Sequence 
>gi|15607494|ref|NP_214867.1| heat shock protein transcriptional repressor HspR [Mycobacterium tuberculosis H37Rv] MAKNPKDGESRTFLISVAAELAGMHAQTLRTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRIIELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWKPRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hspR is attenuated in mice (Stewart et al., 2001).
COG COG0789K, under K: Transcription
References
Stewart et al., 2001: Stewart GR, Snewin VA, Walzl G, Hussell T, Tormay P, O'Gaora P, Goyal M, Betts J, Brown IN, Young DB. Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection. Nature medicine. 2001; 7(6); 732-737. [PubMed: 11385512].