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dxps

Victor ID 1293
Gene Name dxps
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1197209
NCBI Protein GI 17987781
Locus Tag BMEI1498
Genbank Accession NZ_GG703778
Protein Accession NP_540415
Other Database IDs UniProtKB-ID: D0B1P6_BRUME
UniRef100: UniRef100_C0RHE3
UniRef90: UniRef90_B2S9T6
UniRef50: UniRef50_Q1QQ40
UniParc: UPI00000580C0
EMBL: GG703778
EMBL-CDS: EEW88618.1
RefSeq_NT: NC_003317.1
OMA: QRFPDRY
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1546108
Gene Ending Position 1548039
Gene Strand (Orientation) -
Protein Name 1-deoxy-D-xylulose-5-phosphate synthase
Protein pI 6.56
Protein Weight 64423.23
Protein Length 643
Protein Note catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
DNA Sequence 
>gi|17986284:1546108-1548039 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
TTCAGGCACGAAACGGTGTCGGCAGTGCTTCATGGCCCAGTTCATCGCGATGAAGTGCGGCAAAAACCGT
GCGCACAATGCCCGTACGGTCAAGGCCCGCTTCGGCATACATGGCATCCGGCTTGCCATGGTCCTGATAG
ATATCGGGGAGCGTCAGCGCCCGCACCTTGAAGCCGCGATCCAGAAGCCCGTCCGTGGCGAGGAATTGCA
GCACATGGCTGCCAAACCCGCCGACCGCACCTTCTTCCACCATCACCAGCACTTCATGTTCACGCGCCAG
ACGGCGGATCAGGTCATGGTCGAGCGGCTTGGCGAAACGTGCATCGGCCACTGTCGTCGACAGGCCGGCA
GCGCCCAGTTCTTCAGCGGCTGCAAGACATTCCTGCAAGCGTGTACCGAAGGAAAGAAGCGCCACCTTGG
TGCCTTCGCGCACGATGCGGCCCTTGCCGATTTCCAGCACCGAGCCGCGCTCCGGCAGATCGACGCCCAC
ACCATCACCGCGCGGATAGCGGAAGGAGATCGGGCCTTCGTCATATTCGGCAGCCGTGCGCACCATATGG
CGAAGCTCGGCTTCGTCAGATGCGGCCATCACCACGAAGCCCGGAAGGGCTGCAAGAAAGCCCGTATCGA
ACGAGCCTGCATGGGTGGGGCCATCCGCGCCCACCAGCCCGGCGCGGTCGATGGGGAAGCGCACGGGCAG
GTTCTGGATCGAAACATCGTGCACGACCTGATCGTAGCCGCGCTGGAGAAAGGTGGAATAAATGGCGCAG
AAGGGCTTGTACCCCTCGCTTGCAAGACCGGCAGCGAATGTGACGGCATGCTGCTCGGCAATGCCGACAT
CGAAGACGCGCTTCGGGAAAGCCTCGCCAAAAAGGTCCAGCCCCGTGCCTGTCGGCATGGCGGCGGTGAC
GGCGACGATCTTGTCGTCGTGGCGCGCTTCCTCAATCAGGCTTGTGCCGAAAATCTTGGTGTAGCTCGGC
GCATTTGCCGGGGGCTTCGCCTGCTTGCCGGTGATGACGTCGAACTTGTTGACGCCGTGATATTTGTCGG
CGGCAGCTTCGGCCGGCGCATAGCCCTTACCCTTCTGTGTCACGACATGGATCAGCACCGGGCCTTTCTG
CGTATCGCGGACATTTTTCAGAACCGGCAGCAGGTGGTCGAGATTATGCCCGTCGATCGGGCCGACATAA
TAGAAGCCAAGCTCCTCGAACAGCGTGCCGCCGGTGAAAAAGGCGCGGGCATATTCTTCCGATTTGCGCG
CCTTGTCCTGAAGGAATTTGGGCAGCTTTTGCGCCACCTGCTTCGCCGCCTCGCGCACACTGCGATAGGT
GCGCCCGGAAACGAGGCGCGCCAGATAGGCACTCATCGCGCCCGTCGGCGGCGCAATCGACATATCATTG
TCGTTGAGAATAACGATCAGGCGCGCATCCAGAGCACCGGCATTGTTCATCGCTTCATAGGCCATGCCCG
CTGACATGGAACCATCGCCGATGACGGCGATCACATTGCGCTTTTCGCCCGAAAGCTCGCTCGCCACCGC
CATGCCGAGGCCTGCGGAAATGGAGGTCGAGGAATGGGCCGCGCCAAAGGGATCGTATTCGCTCTCCGCA
CGCTTGGTGAAGCCCGAAAGCCCGCCCGCCTGGCGCAATGTGCGGATGCGGTCGCGCCGCCCGGTCAGGA
TCTTGTGCGGATAGGCCTGATGGCCGACATCCCAGATGATGCGATCATAGGGTGTGTTGAAAACATGATG
CAACGCAACCGTCAATTCCACAACGCCCAAGCCCGCGCCCAGATGCCCGCCCGTGGTGGAAACCGCGTCG
ATCAGCTCGGTGCGCAATTCTTCCGCCAGTTGCGGCAGGTCCTGCTCCGGCAGGGCGCGAAGACGGTCTG
GCGTCGGCGCCTTATCGAGGAGCGGTGTTGAGGGTCGGGACA
Protein Sequence 
>gi|17987781|ref|NP_540415.1| 1-deoxy-D-xylulose-5-phosphate synthase [Brucella melitensis bv. 1 str. 16M]
MSRPSTPLLDKAPTPDRLRALPEQDLPQLAEELRTELIDAVSTTGGHLGAGLGVVELTVALHHVFNTPYD
RIIWDVGHQAYPHKILTGRRDRIRTLRQAGGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVASELSGE
KRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGRTYRSVREAA
KQVAQKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDTQKGPVLIHV
VTQKGKGYAPAEAAADKYHGVNKFDVITGKQAKPPANAPSYTKIFGTSLIEEARHDDKIVAVTAAMPTGT
GLDLFGEAFPKRVFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDR
AGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERG
SVLEIGKGRIVREGTKVALLSFGTRLQECLAAAEELGAAGLSTTVADARFAKPLDHDLIRRLAREHEVLV
MVEEGAVGGFGSHVLQFLATDGLLDRGFKVRALTLPDIYQDHGKPDAMYAEAGLDRTGIVRTVFAALHRD
ELGHEALPTPFRA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Vitamines cofactors (Delrue et al., 2004).

FUNCTION: Thiamine synthesis (Delrue et al., 2004).

MUTATION: Attenuated in Differential fluorescence induction (Delrue et al., 2004).
COG COG1154HI, under H: Coenzyme transport and metabolism; I: Lipid transport and metabolism
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].