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purF from Brucella melitensis bv. 1 str. 16M

Victor ID 1292
Gene Name purF from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1197199
NCBI Protein GI 17987771
Locus Tag BMEI1488
Protein Accession NP_540405.1
Other Database IDs UniProtKB-ID: Q8YFN2_BRUME
UniRef100: UniRef100_Q8YFN2
UniRef90: UniRef90_A5VP19
UniRef50: UniRef50_P77935
UniParc: UPI00000580B6
EMBL: AE008917
EMBL-CDS: AAL52669.1
RefSeq_NT: NC_003317.1
HSSP: P00497
MEROPS: C44.001
GenomeReviews: AE008917_GR
KEGG: bme:BMEI1488
HOGENOM: HBG392416
OMA: GIPFELG
ProtClustDB: PRK09123
BioCyc: BMEL224914:BMEI1488-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1535318
Gene Ending Position 1536868
Gene Strand (Orientation) +
Protein Name amidophosphoribosyltransferase
DNA Sequence 
>gi|17986284:1535318-1536868 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
CGTGCCTCCGCTTTTCCGCGATATGCTTAAGTTGCCTCTGCAATCGAAAGGCCTTGCGGCAATGACCAGC
CATTCTTCTGAAAATGCCCCCTTTATGCTGGATGATGACACCCTGCATGAAGAATGTGGTGTATTCGGCA
TTCTGGGCCATGAGGATGCGGCTGCGCTGACCGCGCTCGGCCTGCATGCGCTCCAGCATCGCGGTCAGGA
AGCCGCCGGCATTGTTTCCTATCATAATCGCCGTTTCCATTCCGAACGCCATATGGGCCTCGTCGGCGAC
CATTTCACCGATGCGGCAACACTGAACCGCCTGCCGGGCAACCGCGCCATCGGCCATGTGCGTTATTCCA
CAACCGGCGAGACGATCCTGCGCAATGTACAGCCGCTGTTTGCGGAACTGGAAGTCGGCGGCATCGCCAT
TGCCCATAACGGCAATTTCACCAATGGCATTACGCTGCGCAAACAGTTGATTGCTTCCGGCGCGATCTTC
CAGGCAACGTCGGATACGGAAGTCGTGCTGCACATGATTGCCCGTTCGCGGCACTCCTCCTCAACCGACC
GTTTCGTGGAAGCGATCCGCCAGGTTGAAGGCGGCTATGCCATGCTGGCGCTTACCCGCACCAAGCTGAT
CGCCGCGCGCGATCCCATCGGCATTCGCCCGCTCGTCATGGGCGAGCTGGACGGCAAGCCGATCTTCTGC
TCGGAAACCTGCGCTCTCGATATTATCGGCGCGAAATATATTCGCGACGTCGAGAATGGCGAAGTGGTAG
TCTGCGAAATCCAGAAGGATGGCTCCATCACCACCCGATCCATCAAGCCGGAAAATCCGCAGCCGGAGCG
GCTGTGCCTTTTTGAATATGTTTATTTCGCACGGCCGGATTCGGTAGTGGGTGGCCGCAGCGTCTATGTG
GCGCGCAAGAACATGGGCATGAACCTTGCCGCCGAGGCGGGCGTGGATGCCGATGTGGTCGTGCCCGTAC
CGGATGGCGGTACGCCGGCAGCGCTGGGCTTTGCGCAGGCAAGCGGTATTCCGTTTGAATATGGCATCAT
CCGCAACCATTATGTGGGCCGCACCTTCATTGAGCCTACACAGCAGATCCGCGCGCTTGGCGTGAAGCTG
AAACATTCAGCCAATCGCGCTATGATTGAAGGCAAGCGGGTCGTTCTGGTGGATGATTCCATCGTGCGCG
GCACCACCTCGGTCAAGATCGTTCAGATGATCCGCGACGCAGGCGCAACCGAAGTCCATATGCGCGTGGC
AAGCCCGATGATCTTCCACCCGGATTTTTACGGTATCGACACCCCCCATGCCGATAAGCTGCTGGCCAAC
CAGCACGAAAGCCTCGAATCCATGTGCCGCTACATCGGCGCCGATTCGCTGGCCTTCCTTTCCATCGACG
GGCTCTACAAGGCCGTTGGCGGAAAGCCGCGTGATCCAAAGGCGCCGACCTTCACCGATCACTATTTCAC
GGGCGAGTATCCGACCCGCCTTCTGGATCAGGAAGGCGAAAGCAACGTCCACACCTTGTCGCTGCTCGCC
AGCAACGGCTG
Protein Sequence 
>gi|17987771|ref|NP_540405.1| amidophosphoribosyltransferase [Brucella melitensis bv. 1 str. 16M] MPPLFRDMLKLPLQSKGLAAMTSHSSENAPFMLDDDTLHEECGVFGILGHEDAAALTALGLHALQHRGQEAAGIVSYHNRRFHSERHMGLVGDHFTDAATLNRLPGNRAIGHVRYSTTGETILRNVQPLFAELEVGGIAIAHNGNFTNGITLRKQLIASGAIFQATSDTEVVLHMIARSRHSSSTDRFVEAIRQVEGGYAMLALTRTKLIAARDPIGIRPLVMGELDGKPIFCSETCALDIIGAKYIRDVENGEVVVCEIQKDGSITTRSIKPENPQPERLCLFEYVYFARPDSVVGGRSVYVARKNMGMNLAAEAGVDADVVVPVPDGGTPAALGFAQASGIPFEYGIIRNHYVGRTFIEPTQQIRALGVKLKHSANRAMIEGKRVVLVDDSIVRGTTSVKIVQMIRDAGATEVHMRVASPMIFHPDFYGIDTPHADKLLANQHESLESMCRYIGADSLAFLSIDGLYKAVGGKPRDPKAPTFTDHYFTGEYPTRLLDQEGESNVHTLSLLASNG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A B. suis purF mutation experiment suggests that the purine biosynthesis pathway contributes to intracellular growth (Kim et al., 2003).
COG COG0034F, under F: Nucleotide transport and metabolism
References
Kim et al., 2003: Kim S, Watarai M, Kondo Y, Erdenebaatar J, Makino S, Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infection and immunity. 2003; 71(6); 3020-3027. [PubMed: 12761078].