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thrC from Brucella melitensis bv. 1 str. 16M

Victor ID 1290
Gene Name thrC from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1197161
NCBI Protein GI 17987733
Locus Tag BMEI1450
Protein Accession NP_540367.1
Other Database IDs UniProtKB-ID: D0B1U3_BRUME
UniRef100: UniRef100_D0B1U3
UniRef90: UniRef90_A6WWH6
UniRef50: UniRef50_Q48LV3
UniParc: UPI0000058090
EMBL: GG703778
EMBL-CDS: EEW88665.1
RefSeq_NT: NC_003317.1
OMA: YYFTSAV
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1498739
Gene Ending Position 1500130
Gene Strand (Orientation) +
Protein Name threonine synthase
DNA Sequence 
>gi|17986284:1498739-1500130 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
AATGAAATATGTAAGTACGCGTGGGGAAGCACCGGTTCTGGGATTCAGCGATGCATTGCTCGCAGGCCTC
GCCCGTGATGGCGGTCTTTATCTGCCGCAGGAATATCCGCAATTCACAGCCGAACAGATCCGCGCCCTGC
GTGGAAAATCCTATGTCGAAGTCGCGCTGGCCGTCCTCACGCCCTTTACCGGCGGTGAAATTCCGGCAGC
CGATTTCGAGCGCATGGTCCGCGAAGCTTACGGAACCTTCCGTCACGATGCCGTCTGCCCGTTGGTGCAG
ACCGACGCGAACGAATTCGTGCTGGAGCTTTTCCATGGCCCCACCCTTGCCTTCAAGGATGTCGCCATGC
AGCTTCTGGCCCGCATGATGGATTATGTTCTGGCACAGCGCGGCGAGCGCGCAACGATCGTCGGCGCTAC
ATCCGGCGATACGGGCGGCGCAGCCATCGAAGCCTTTGGCGGGCGCGACAACACAGACATTTTCATCCTG
TTCCCCAATGGGCGGGTCTCGCCGGTACAGCAACGCCAGATGACGTCTTCCGGCTTTTCCAATGTCCATG
CGCTTTCCATCGAGGGCAATTTCGACGATTGCCAGAACCTCGTAAAAGGCATGTTCAATGATCTGGAATT
CTGTGACGCCCTGTCGCTTTCCGGCGTGAACTCGATCAACTGGGCGCGCATCATGCCGCAGGTTGTCTAT
TATTTCACGGCAGCACTCAGCCTCGGCGCACCGGACCGCGCCGTGTCCTTCACGGTGCCCACCGGCAATT
TCGGCGATATTTTCGCAGGCTACGTCGCCAAGCGCATGGGCCTGCCCATCGAGCAACTCATCATCGCCAC
CAACGACAACGATATTCTTTCGCGCACGCTGGAAAGCGGGGCCTATGAGATGCGCGGCGTAGCGCAGACC
ACTTCGCCCTCAATGGATATCCAGATTTCCTCCAATTTCGAGCGGCTTCTGTTCGAGGCACACGGGCGCG
ATGCGGCGGCCGTGCGCGGGCTGATGCAGGGCCTGAAGCAATCTGGCGGATTTACGATTTCCGAAAAGCC
GCTTTCGGCCATCCGCAGCGAATTTTCGGCTGGCCGCTCCACCGTCGATGAGACGGCGGCGACTATCGAA
TCGGTTCTTTCCAAAGACGGCTATCTGCTTGATCCGCATTCGGCGATCGGTGTGAAGGTCGCGCGTGAAA
AAGCATCCGGCACCGCCCCGATGGTGGTTCTGGCGACCGCCCATCCGGCCAAATTCCCGGATGCGGTGAA
GGCTGCATGTGGGGTCGAGCCGCAATTGCCGGCATGGCTTTGCGACCTGATGCAACGAAAAGAGAGCTTC
ACAGTTCTTCACAACGAGCTGAAAATCGTGGAAGAATATGTGCGCCACCATTCCCGAGCCTG
Protein Sequence 
>gi|17987733|ref|NP_540367.1| threonine synthase [Brucella melitensis bv. 1 str. 16M] MKYVSTRGEAPVLGFSDALLAGLARDGGLYLPQEYPQFTAEQIRALRGKSYVEVALAVLTPFTGGEIPAADFERMVREAYGTFRHDAVCPLVQTDANEFVLELFHGPTLAFKDVAMQLLARMMDYVLAQRGERATIVGATSGDTGGAAIEAFGGRDNTDIFILFPNGRVSPVQQRQMTSSGFSNVHALSIEGNFDDCQNLVKGMFNDLEFCDALSLSGVNSINWARIMPQVVYYFTAALSLGAPDRAVSFTVPTGNFGDIFAGYVAKRMGLPIEQLIIATNDNDILSRTLESGAYEMRGVAQTTSPSMDIQISSNFERLLFEAHGRDAAAVRGLMQGLKQSGGFTISEKPLSAIRSEFSAGRSTVDETAATIESVLSKDGYLLDPHSAIGVKVAREKASGTAPMVVLATAHPAKFPDAVKAACGVEPQLPAWLCDLMQRKESFTVLHNELKIVEEYVRHHSRA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: a.a. metabolism, Synthesis (Delrue et al., 2004).

FUNCTION: Thre. Synthesis (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages (Delrue et al., 2004).
COG COG0498E, under E: Amino acid transport and metabolism
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].