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hrcA

Victor ID 129
Gene Name hrcA
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885924
NCBI Protein GI 15609511
Locus Tag Rv2374c
Protein Accession NP_216890.1
Other Database IDs UniProtKB-ID: HRCA_MYCTU
UniRef100: UniRef100_C1AQT7
UniRef90: UniRef90_C1AQT7
UniRef50: UniRef50_A3Q272
UniParc: UPI000012CBA4
EMBL: BX842579
EMBL: AE000516
EMBL-CDS: CAB08478.1
EMBL-CDS: AAK46737.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000003056
EnsemblGenome_TRS: EBMYCT00000003058
EnsemblGenome_PRO: EBMYCP00000003058
EnsemblGenome: EBMYCG00000068947
EnsemblGenome_TRS: EBMYCT00000068952
EnsemblGenome_PRO: EBMYCP00000067011
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 2654061
Gene Ending Position 2655092
Gene Strand (Orientation) -
Protein Name heat-inducible transcription repressor
DNA Sequence 
>gi|57116681:2654061-2655092 Mycobacterium tuberculosis H37Rv, complete genome
TTCATCGAGCACCCAGGACGTCGCCGATATAAAGAGCAACCGCAGCCACGCTGGCGATAGTTCCCGGATA
GTCCATCCGGGTGGGGCCCACCACACCCATACCGCCGTAGACGGTATGGGCGGTACCGTAGGCCGTCGAC
ACCATCGAGGTGCCCACCATCTGCTCAGACGCCGTCTCATGACCTATGCGAACCGTCACCTTGCCGGCTT
CCTGCTGAGCCGCCAGCAGCCGCAACACCACCACCTGCTCCTCAAGTGCTTCCAATATTGACCGCAGTGA
ACCACCGAAGTCCGCAGCGTTGCGGGTTAGGTTGGCGGTACCGCCCAGCAAAAGGCGTTCCTCGGTGTGC
TCCACTAGCGACTCCAGCAATACGGTCGCCGCGCGGCCCACGGCGTCGCCCAATCCGCCGGCGCCGCCCA
GCTGGCTGGCGAGGTCGGCGACCGCCACCGAAGCCGCTGAAAGCTTCTTGCCTTCCAGCGCCTGGCCGAG
TATTTCACGCAGCTGGGCTAGCTGGTGATCGTCGATGACATCGCCGAGTTCGACGATGCGCTGATCAACC
CGGCCGGAGTCGGTGATGACCACCATCAGCAGCCGGGCCGGTGTCAGCGCGATCACCTCCAAGTGGCGAA
CGGTCGACGTTGACAACGTCGGGTACTGCACGACGGCCACCTGGCGGGTCAGCTGCGCCAGCAATCGCAC
GGCACGGCGCAGCACGTCGTCGAGATCGACACCGGATTCAAGGAAGCTCTGGATCGCCCGGCGCTCGGCC
GACGATAGGGGTTTGACGTCCTCGAGCCGGTCGACGAACTCGCGGTAGCCCTTCTCCGTGGGCACGCGTC
CGGAACTGGTGTGTGGCTGAGTGATATAGCCTTCGGCTTCCAGCACCGCCATGTCATTGCGGACTGTGGC
CGACGAGACTCCCAGGTTATGGCGTTCCACCAGGGATTTGGAGCCGATCGGTTCCTGGGTTGCAACGAAG
TCGGCGACGATGGCACGCAGCACCTCAAAGCGACGCTCGTCGGCGCTTCCCA
Protein Sequence 
>gi|15609511|ref|NP_216890.1| heat-inducible transcription repressor HrcA [Mycobacterium tuberculosis H37Rv] MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1420K, under K: Transcription
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].