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BMEI1448

Victor ID 1289
Gene Name BMEI1448
Sequence Strain (Species/Organism) Brucella
NCBI Gene ID 1197159
NCBI Protein GI 17987731
Locus Tag BMEI1448
Protein Accession NP_540365.1
Other Database IDs UniProtKB-ID: Q8YFS2_BRUME
UniRef100: UniRef100_D0B1U5
UniRef90: UniRef90_B2S9Y1
UniRef50: UniRef50_B2S9Y1
UniParc: UPI000005808E
EMBL: AE008917
EMBL-CDS: AAL52629.1
RefSeq_NT: NC_003317.1
GenomeReviews: AE008917_GR
KEGG: bme:BMEI1448
NMPDR: fig|224914.1.peg.1447
HOGENOM: HBG365956
OMA: TERTTEA
ProtClustDB: CLSK898437
BioCyc: BMEL224914:BMEI1448-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1495791
Gene Ending Position 1497371
Gene Strand (Orientation) -
Protein Name C-DI-GMP PHOSPHODIESTERASE A-RELATED PROTEIN
DNA Sequence 
>gi|17986284:1495791-1497371 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
CTCATTTCGCCTTTTGGGTCGTTTTGCGGGCCAACTTCACGCGCGATTGCTTCTTCTTCACTGTAGCGAC
CAGCGCCTGCGCATCGGAAACGCACAGCGGCTTGCCAAAAAACCAGCCTTGTGCGGCCAGGGGCGTGCCC
AGTTTACGAAAATAGAGGACCTGTGCCTCCGTTTCCACCCCTTCGACCACGATATCGAGGCCATGTTCCT
TCGCCATGGAAATGATCTGCGGAATGATGGAGACCGTTGCGTAATCATTGCCGACAGTGCGCGTGAAAGC
CTTGTCGATCTTGATTGCGTCCACATGCAATTCGCCGAGATAGGCAAGGCTCGAATAGCCGGTGCCGAAA
TCGTCGATATAAATCCGGTGCCCCTGCTCGCGCAGGCGCCTGATGCCGTCCGTCGCCTTGGAAAAATCGA
CCGCCGTGCGTTCCGTCAGTTCCAACCCCACCTGTTGTGGTTCGATATCAGCCGCCGCAAGGCGCCTTTC
CATCCGGCTCATGAAGGCCGGGCTTTGCAGGTCGCTGGCGGTAATGTTGATATTGATACGCAAATCACGG
CGCTGGCGCAGCGTGTCGCCCATGTCTTCTATCAGACGTTCCAGCACATAGATCGTTATCTTTGTAGCGG
TGCCCGCCTCCTCCGCCCGCGCAACGAAGACATCCGGCGGGACGAAATCGCCCTTGCGGATTTCCCATCG
GATCAATGCTTCAAAGCCGAGCACCTTGCCATCCGCCATATCCACCACCGGCTGGTAGAGCAAATGCGGC
TCTCCGGCAGCGAGTGCCTTGTTCAGCCTGTAGAGCAATGAGTGGTCGCGATTGCGATAATAGAGCCAGC
CCAGCCCGACACTGCCACCCGCCAATGCGCCAAGGCAGATGGCCAGCAGGTTTTTCAGCCGTGCTGCCGT
GCTGGTTCGGTCGATCGTTGCTGACAGGCTGATGCAGACGCCCGTATCCGGGTCACAGCTATTCTCCCGC
AACACCTTGCCATCCGGCGCTTCCACGAATTTCTGCGCCCAATCACCAGAGGACGGCTCAGGTCCAGGCT
CGGCATTACCTGAATAATTGTAAAGCAGCGCGAAATGCTTCTTTTCCTCGTCGGTGGCAAAAATGGAAAA
AGCATAGCGCGGCGTGTGCAGGAGATCGAAGGCAACCGAGCTCAAGACCACATTCGCATTCCCTCGTCCG
ATGATCGGCCCATGGCTACCCGGCGTTATCAAGGCATCATCGGCATAGATATAGGTTCCGTCCTTCAAAT
TGTCATTGGCAACGGAACGGCGCGGCTGAGTTTTGATATCACTCAGAAGCGTCGAGCAGATAAGTTGGTC
ATCGCGCAGACGCCCGATATCCTTGATGTGATAGGCGGCAAAGACGAGCTTGCGCTGATAGGCAAGATCC
TGCGGGGAACATATCTCGAAGGGAGAATTATTCGCAGCCTCCAGAGTATTCCTCGCGGAGGCGAGCAGCC
GGCTGGAGTAATCGCGCAGAGCCGTCATATAGATATCCATATGACGTTCTTCTTCGAGAATGCGGAGTCC
TTTTCCGACCAGTTGCCCGGCCACGGCCCCCAGAATAAGCA
Protein Sequence 
>gi|17987731|ref|NP_540365.1| c-di-GMP phosphodiesterase A-related protein [Brucella melitensis bv. 1 str. 16M] MLILGAVAGQLVGKGLRILEEERHMDIYMTALRDYSSRLLASARNTLEAANNSPFEICSPQDLAYQRKLVFAAYHIKDIGRLRDDQLICSTLLSDIKTQPRRSVANDNLKDGTYIYADDALITPGSHGPIIGRGNANVVLSSVAFDLLHTPRYAFSIFATDEEKKHFALLYNYSGNAEPGPEPSSGDWAQKFVEAPDGKVLRENSCDPDTGVCISLSATIDRTSTAARLKNLLAICLGALAGGSVGLGWLYYRNRDHSLLYRLNKALAAGEPHLLYQPVVDMADGKVLGFEALIRWEIRKGDFVPPDVFVARAEEAGTATKITIYVLERLIEDMGDTLRQRRDLRININITASDLQSPAFMSRMERRLAAADIEPQQVGLELTERTAVDFSKATDGIRRLREQGHRIYIDDFGTGYSSLAYLGELHVDAIKIDKAFTRTVGNDYATVSIIPQIISMAKEHGLDIVVEGVETEAQVLYFRKLGTPLAAQGWFFGKPLCVSDAQALVATVKKKQSRVKLARKTTQKAK
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Unkown function (Delrue et al., 2004).

FUNCTION: EAL domain (Delrue et al., 2004).

MUTATION: Attenuated in Mice, Macrophages, HeLa (Delrue et al., 2004).
COG COG4943T, under T: Signal transduction mechanisms
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].