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rfbD from Brucella melitensis bv. 1 str. 16M

Victor ID 1284
Gene Name rfbD from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1197124
NCBI Protein GI 17987696
Locus Tag BMEI1413
Protein Accession NP_540330.1
Other Database IDs UniProtKB-ID: D0B1X8_BRUME
UniRef100: UniRef100_D0B1X8
UniRef90: UniRef90_D0B1X8
UniRef50: UniRef50_O60547
UniParc: UPI000005806B
EMBL: GG703778
EMBL-CDS: EEW88700.1
RefSeq_NT: NC_003317.1
OMA: TQRVDHI
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1461048
Gene Ending Position 1462136
Gene Strand (Orientation) +
Protein Name GDP-mannose 4,6-dehydratase
DNA Sequence 
>gi|17986284:1461048-1462136 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
CGTGAAGAAAGTCGCACTTATCACAGGTATCACCGGCCAAGACGGCGCCTACCTTGCGGAATTGCTTCTA
CAAAAAGGTTATGCAGTACACGGGATTAAGCGTCGCACCTCGCAATTTAACACAGCACGTATCGATCATC
TGTACCATGATCCGCACGAGCAGGGTGTCGATCTAACACTTCATCATGGCGATCTAACAGATACGTCAAG
CTTGGTTCGAATCATGCAGCTCGTTCGGCCGGATGAAGTTTATAACCTTGGCGCACAAAGCCATGTTGCT
GTTTCATTTGAGGAGCCGGAGTATACTGCGAACTCAGACGCACTAGGTGCCCTTCGTCTGCTAGAGGCGA
TCCGAATTCTTGGAATGGAGAAGCAGACCCGGTACTACCAAGCATCCACCTCTGAGCTTTATGGTCTGGT
TCAAGAAATCCCGCAAAAAGAAACGACGCCTTTTTACCCTCGGTCGCCCTATGCCGCAGCGAAGCTTTAT
GCCTATTGGATTACGGTAAACTACCGAGAAGCGTATGGTATATATGCTTGTAATGGCATACTTTTTAACC
ATGAATCTCCACTTAGAGGAGAGACTTTTGTCACGAGAAAAATTACTCGCGCTTTAGCTAGAATTAAGAT
CGGTAATCAGAATCGCTTATACTTAGGGAATTTGGACTCATTACGCGACTGGGGGCATGCTCGGGACTAC
GTCGAGATGCAGTGGTTAATGCTTCAACAGGATCAACCAGAAGATTTTGTAATAGCAACTGGTAAACAAT
ATTCAGTTCGAGAATTTGTCACGCTCGCTGCTAAAGACATAGGCATTGAGATGCGATGGGAAGGTAGCGG
TGAAGCCGAGAAGGGTTATGATGCCAAGACCGGTGCATGTATTGTCGAGGTCGATCCTAGATACTTTCGA
CCAGCCGAGGTGGAAACTCTTCTGGGAGATGCGACCAAGGCGCATCAAAAACTGGGCTGGAAGCCGAAAA
TCTCTTTTGAGACGCTTGTATCTGAGATGATAGCAGAAGACTTAGCGGCGGCGGCTCGTGAGAATTTGCT
GCGCGAACATGGTCACCAATTTTTCGCCCCTAAGGAATG
Protein Sequence 
>gi|17987696|ref|NP_540330.1| GDP-mannose 4,6-dehydratase [Brucella melitensis bv. 1 str. 16M] MKKVALITGITGQDGAYLAELLLQKGYAVHGIKRRTSQFNTARIDHLYHDPHEQGVDLTLHHGDLTDTSSLVRIMQLVRPDEVYNLGAQSHVAVSFEEPEYTANSDALGALRLLEAIRILGMEKQTRYYQASTSELYGLVQEIPQKETTPFYPRSPYAAAKLYAYWITVNYREAYGIYACNGILFNHESPLRGETFVTRKITRALARIKIGNQNRLYLGNLDSLRDWGHARDYVEMQWLMLQQDQPEDFVIATGKQYSVREFVTLAAKDIGIEMRWEGSGEAEKGYDAKTGACIVEVDPRYFRPAEVETLLGDATKAHQKLGWKPKISFETLVSEMIAEDLAAAARENLLREHGHQFFAPKE
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: "Classical virulence factors", Envelope molecules, Lipopolysaccharide (Delrue et al., 2004).

FUNCTION: O-chain biosynthesis (Delrue et al., 2004).

MUTATION: Attenuated in Mice, Macrophages (Delrue et al., 2004).
COG COG1089M, under M: Cell wall/membrane/envelope biogenesis
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].