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pyrC from Brucella melitensis bv. 1 str. 16M

Victor ID 1273
Gene Name pyrC from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1196992
NCBI Protein GI 17987564
Locus Tag BMEI1281
Protein Accession NP_540198.1
Other Database IDs UniProtKB-ID: Q8YG80_BRUME
UniRef100: UniRef100_D0B2A2
UniRef90: UniRef90_D0B2A2
UniRef50: UniRef50_D0B2A2
UniParc: UPI0000057FEA
EMBL: AE008917
EMBL-CDS: AAL52462.1
RefSeq_NT: NC_003317.1
HSSP: P81006
GenomeReviews: AE008917_GR
KEGG: bme:BMEI1281
HOGENOM: HBG724623
OMA: ERARGCA
ProtClustDB: PRK09060
BioCyc: BMEL224914:BMEI1281-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1328794
Gene Ending Position 1330230
Gene Strand (Orientation) -
Protein Name dihydroorotase
DNA Sequence 
>gi|17986284:1328794-1330230 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
GTCAGCGACGGGGCAGCGCTTCGAGGAACTCCACCGGCTCGCCCTTGTGAGGATTGACGATTTCCGCCTC
CCACATCACCTTGATGCCGCGCACGAAAGTGCCAACCGGCCATCCGGTGACGGTCTTGCCATGATAGGGC
GTCCAGCCGGCTTTCGATCCTGCCTGTTCATGCGTGATCGTTTCGCGGCGTTTCATGTCCACGATCGTCA
GATCGGCATCGTAGCCGACCGCGATGCGCCCCTTGCGCGCCATGCCGAAAATGCGGTTCGGGCCGTGGCT
GGAAAGATCGACAAAACGCTCCAGTGAAAGCTTACCGGCATTCACATGGTCCAGCATGATCGGCACCAGC
GTCTGCACGCCGGTCATGCCCGATGGGGAAGCCGGATAAGACTTCTGCTTTTCTTCCAGCGTGTGCGGGG
CATGGTCTGAACCCAGCACATCCACGATACCCTGATCGATCCCCTTCCACACACCTTCACGGTGGCGCTT
GTCACGCACCGGCGGGTTCATCTGGATGAGATTGCCAAGCGCCTTGTAATCATCCGCCGACAGGGTGAGG
TGATGCGGCGTCGCCTCGCAGGTGGCGACGTCCTTGTAATCTTTCAGGAAGTCGATTTCCTCGGCGGTCG
AAATATGCAGCACATGAATGCGCGCGCCAGTCTCGCGGGCGATGCGTACCAGGCGCTGCGTGCATTGAAG
CGCGGCAATCTCGTCGCGCCATACCGGATGGCTCGATGGATCACCCTCAACGCGCAATCCTTCACGTTCC
TTGAGCCGAAATTCGTCTTCGGAATGAAAAGCCGCGCGGCGGCGCGTATTCCTCAGGATCGAGCGTACGC
CATCATCGTCCTCAACCAGAAGATCGCCGGTGGACGAACCCATGAATACCTTGATGCCCGCCGCGCCCGG
CAGGCGCTCCAGTTCGGCCACGTCCTTCGCATTATCGCGCGTGCCGCCGACCCAGAAGGCGAAATCGCAA
TGCATCCGATGGCGGCCACGGCGAATCTTGTCTTCCAGCATTTCGGCCGAAGTGGTCAGCGGCTTGGTGT
TCGGCATTTCAAAAACGGCCGTCACGCCGCCCAGCACGGCGGCAAGTGACCCGGTTTCCAGATCTTCCTT
GTGCTCAAGACCCGGCTCGCGGAAATGAACCTGGCTATCCACAACGCCGGGTAGGATATGCAGGCCAGTG
CAGTCAATCACTTCACCGGCTGAGTTCCCTGCAAGCGACCCGATAGCGGCGATGCGTCCGTTACGAATGC
CAATGTCGCGCTGGCCGATACCGTCATGATTGACGATGGTTGCGCCTTTCAAAATCGTATCGAATGTTGC
GGCCATGGGTGTCTCCTGCTTTTCGGATGGGACTTGCGAGCCTTTACATTGGGGCTTACGTAACGAGGGC
GCGAAAGGCAAGGACGAAGCGATGATGACGGCATCCA
Protein Sequence 
>gi|17987564|ref|NP_540198.1| dihydroorotase [Brucella melitensis bv. 1 str. 16M] MDAVIIASSLPFAPSLRKPQCKGSQVPSEKQETPMAATFDTILKGATIVNHDGIGQRDIGIRNGRIAAIGSLAGNSAGEVIDCTGLHILPGVVDSQVHFREPGLEHKEDLETGSLAAVLGGVTAVFEMPNTKPLTTSAEMLEDKIRRGRHRMHCDFAFWVGGTRDNAKDVAELERLPGAAGIKVFMGSSTGDLLVEDDDGVRSILRNTRRRAAFHSEDEFRLKEREGLRVEGDPSSHPVWRDEIAALQCTQRLVRIARETGARIHVLHISTAEEIDFLKDYKDVATCEATPHHLTLSADDYKALGNLIQMNPPVRDKRHREGVWKGIDQGIVDVLGSDHAPHTLEEKQKSYPASPSGMTGVQTLVPIMLDHVNAGKLSLERFVDLSSHGPNRIFGMARKGRIAVGYDADLTIVDMKRRETITHEQAGSKAGWTPYHGKTVTGWPVGTFVRGIKVMWEAEIVNPHKGEPVEFLEALPRR
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: DNA/RNA metabolism, Synthesis (Delrue et al., 2004).

FUNCTION: dihydroorotase (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages, HeLa (Delrue et al., 2004).
COG COG0044F, under F: Nucleotide transport and metabolism
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].