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amiC from Brucella melitensis bv. 1 str. 16M

Victor ID 1260
Gene Name amiC from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1196767
NCBI Protein GI 17987339
Locus Tag BMEI1056
Genbank Accession AE008917
Protein Accession NP_539973
Other Database IDs UniProtKB-ID: Q8YGV1_BRUME
UniRef100: UniRef100_Q8YGV1
UniRef90: UniRef90_E2PJL1
UniRef50: UniRef50_C6AUW1
UniParc: UPI0000057F09
EMBL: AE008917
EMBL-CDS: AAL52237.1
RefSeq_NT: NC_003317.1
GenomeReviews: AE008917_GR
KEGG: bme:BMEI1056
NMPDR: fig|224914.1.peg.1055
HOGENOM: HBG656726
OMA: DQVGTIN
ProtClustDB: CLSK862937
BioCyc: BMEL224914:BMEI1056-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 1097648
Gene Ending Position 1098820
Gene Strand (Orientation) -
Protein Name N-acetylmuramoyl-L-alanine amidase
Protein pI 9.75
Protein Weight 40814.23
Protein Length 390
Protein Note 3.5.1.28
DNA Sequence 
>gi|17986284:1097648-1098820 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
ACTATCCGCCGCTGAGATTTGAGGGTCTCTTGCGCGCGGCAAAGGCCTTCACCGCAAGTGCGATCCTGTC
TGCCAGTTTTTTACGCCATTCCGGGTTGCTGATGAGTTTTTCATCCTCCGGGTTGGAAAGATAGCCAATC
TCAATCAGCACGGAAGGAACATCGGGTGCCCGCAGAACCTGAAAGCCGGCGAAGCGATGCGGATTATTAA
TGAGGTTCACCTGCCCCTGCAATTCGCCAATCACCTTTTCGGCAAAGCTTAAGGAGAAGGTGTGCGTTTC
GCGCCGCGTGAGGTCGAGCAGGATATCGGTGACTTCGGGCTGTTCTTCCGGCAGCGCGCCGGCCAGACTG
TCGGACTTGTTTTCACGCTCCGCCATGGCGCGCGCAACAGCGTCCGACGCCTTGTCGGAAATCGTATAGA
CGGTCGCCCCGCGAATATCGTGCTGGTTGATGGTATCGGCGTGAATGGAGATAAAAAGGTCTGCTTCATG
CTGGCGCGCCAGACGCACCCGCTCAGCCAGGCGCAGGAACGTGTCGTCCTCGCGCGTCATCAAAACCTTG
ATGTTCCGTTCATGGGAGAGCCTGTCACGCAACTCCTTGCCGAAGGCGAGCGTCAGGTTCTTTTCCTTGT
TTCCACTCAGGCTTTCCGCACCGCTGTCTATGCCGCCATGGCCGGGATCGATCATCACCGTAAAGGGTCG
CGGCTTGCCATTCCCCGGCAGGGCTGAACCAGCCACCTGTTGCCGGGCCCGCTCGGTCGAGCCGGTTTTA
CCTTTCTGCTCCTTGAGCTTTTCGGCGAACTTCCTGTCAGAGGTTGCGACAATATCCGCCACCAAGCGAT
AGCCGGAGGCGTTCTCATTTTTGAGAACACGAAGGTTTTCGACATCGAAAGCCCCCCGCAAGGTGAGAAT
CAGCCGCGAACACCCCTTCCCCGCCAGGCCATAACGCACGTGCGAAACAAGCCCCCTCGCCTCAAGGCTT
TTTTCATCGAAGCCGAAACGGGTTTCCGGCAGATCGATCACCAGACGATGCGGATTGCCAAACAGCCGTG
TTGAAAGCTTCGGTTCCCGATCGAACATTACAACGACGCGCGTGCGCAGATCATCGCCAGCCATACGAAA
TGTGAGGGCCGAAAGTGGCGGAGCCGGGCTATCGGCAGCAAAAGTGGAAGGCA
Protein Sequence 
>gi|17987339|ref|NP_539973.1| N-acetylmuramoyl-L-alanine amidase [Brucella melitensis bv. 1 str. 16M]
MPSTFAADSPAPPLSALTFRMAGDDLRTRVVVMFDREPKLSTRLFGNPHRLVIDLPETRFGFDEKSLEAR
GLVSHVRYGLAGKGCSRLILTLRGAFDVENLRVLKNENASGYRLVADIVATSDRKFAEKLKEQKGKTGST
ERARQQVAGSALPGNGKPRPFTVMIDPGHGGIDSGAESLSGNKEKNLTLAFGKELRDRLSHERNIKVLMT
REDDTFLRLAERVRLARQHEADLFISIHADTINQHDIRGATVYTISDKASDAVARAMAERENKSDSLAGA
LPEEQPEVTDILLDLTRRETHTFSLSFAEKVIGELQGQVNLINNPHRFAGFQVLRAPDVPSVLIEIGYLS
NPEDEKLISNPEWRKKLADRIALAVKAFAARKRPSNLSGG
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: "Classical virulence factors", Envelope molecules, peptidoglycan (Delrue et al., 2004).

FUNCTION: Cell-wall hydrolysis (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages, HeLa (Delrue et al., 2004).
COG COG0860M, under M: Cell wall/membrane/envelope biogenesis
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].