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ntrY from Brucella melitensis bv. 1 str. 16M

Victor ID 1248
Gene Name ntrY from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1196578
NCBI Protein GI 17987150
Locus Tag BMEI0867
Protein Accession NP_539784.1
Other Database IDs UniProtKB-ID: D0B9D0_BRUME
UniRef100: UniRef100_D0B9D0
UniRef90: UniRef90_A9M5C9
UniRef50: UniRef50_A5VQP0
UniParc: UPI0000057E4D
EMBL: GG703780
EMBL-CDS: EEW86786.1
RefSeq_NT: NC_003317.1
OMA: RIVRPIR
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 894291
Gene Ending Position 896546
Gene Strand (Orientation) +
Protein Name NITROGEN REGULATION PROTEIN NTRY
DNA Sequence 
>gi|17986284:894291-896546 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
CATGAATGGGACGAGGCAATCATCGCAAGATGAGGGGCAGGGTGAGGGGCGCAGGCTTCTCGCCTTACCG
GGTATTATTACCGTCGTTTCGGCGCTGGTCACAGCTTCGTTTTCCTTCGCGATCCTGATCGGTATTACGC
CAATCACCCCCGACCGCACGGTTACACTGGCGCTGGTGATTATCAATGTCGCGTTGATTTTGTTTCTGAT
CCTGCTGATTTGCCGCGAGGTCTATCGCATCATAACGGCGCGTAGGCTGGGCAAGGCCGCGTCGCGCCTG
CATGTGCGCATTGTAGCCCTGTTTTCGCTGATTGCCGCCATTCCGGCAATCGTGGTGGCAATTGTCGCTT
CCGTGACCCTCAATCTGGGCCTTGATCGCTGGTTCGACCAGAATACACGCGACATCATCAGTTCATCCCA
GAATTTCTATACAGCCTATCTTCAGGAAACCGCGTTGAACCTCCAGAGCACGTCCTATTCGATGTTGCAG
GATCTGGATGCGCAGCGTGCCATTTATAGCCTCGACCGGAACGGTTTCATCCAGTTGATGACATTGCAGG
TGCGTGGGCGCGCCTTGCTGGGCGCATTTCTGGTGCGTGATAATGGCGATGTCGTCGTGCAGAGCGATAC
GGGCATGGAAAGCCATCTGCCGCCGCCGACGAAGGATTCGCTTGAAAAGGCACCGGACGGAAAGCCTGTC
ATCATCCCGCCGGGAAACACCAATTTCGTCGGTGCACTCATCAAGATGCGCGAAATTCCCGACATGTATC
TTTATACGGTGCGTTCGGTTCCGCCGCAAATTCTTGATGCCATCAATCTGATGAATGCCAATGCCAGGCG
CTATCAGGAAATGGATGCGAACCGCATTCCGACGCAGATTGCTTTCGCTTTGCTCTATTTCGGCCTGACG
CTGATCGTGCTTCTGTCGGCCATCTGGACGGGCATTGCCGTTGCAGACCGGCTGGTGCGGCCAATCCGGC
TGCTGATCGGCGCATCGGACGATGTGGCTGCCGGCAATCTTGATGTTTCGGTGCCGGTGCGCTCGTCCGA
TGGCGATGTGGGGGCGCTGTCGGGTACTTTCAACAACATGGTTGCCGAGCTGAAAAGCCAGCGCAACGAA
CTTATTTCCGCCAAGGACCAGATCGATGAGCGCCGCCGCTTCTCCGAAGCCGTGCTTTCGGGTGTGACGG
CAGGGGTTATCGGTATTGAGAATGACGGGTCGATTTCGATCCTCAACCGCTCTGCGGAGCATATGTTTGG
CGTAACGTCGGAAGATGCGGTCGGGAAAAGCCTTACCAGCATCGCGCCGGAGGTCGGGCAGGCTTTCGAG
GTGGCGCGCGCCACGGGGCGAACCGTGCACCGCGAGCAGGTGAGCATGGCGCGCGGCGGCGGTAGCCGCA
GCTTCAATGTGCAGGTAACGGTCGAGGATGCCGAATCCGAGGATCACTCCTATGTGGTGACGGTGGACGA
CATCACCGATCTGGTGCAGGCGCAACGTTCTTCCGCATGGGCGGATGTGGCGCGGCGCATCGCGCATGAA
ATCAAGAATCCGCTGACGCCGATCCAGCTTTCGGCAGAGCGCATCCGCCGCCGGTATGGCAAGGTCATCA
CGGAGGATCGCGAGGTTTTCGACCAGTGCACGGACACCATCATTCGTCAGGTCGGCGATATTGGCCGCAT
GGTCGATGAGTTCTCCGCTTTTGCGCGTATGCCCCAGCCGGAAATGCGGCATATGGACCTGCGCGAAGCA
TTGCGTGAAGCCTCGTTCCTGATTGAAGTCAGCCGCAGCGACATTCATTTCGACAATGATTTCGGTTCGG
AAAAGCTGATTGGATCGTTCGATAGCCGCCTGATCGGGCAGGCCTTCGGCAATGTCATCAAGAATGCCAG
CGAGGCCATTGACGCGGTTGCGAAGGAAGAGCGCGGCGAGGGGCATATCCGCATTCACGCCTACAGGGCG
GATGGGCAACTGGTGGTCGATGTGATCGACAACGGCAAGGGCTTGCCCGGCGATGATCGCCAGAAACTGC
TGGAACCCTATATGACGACCCGCGAAAAGGGAACGGGCCTTGGCCTCGCAATCGTTCGCAAGATTGTTGA
AGATCATGGCGGTAATCTTGAATTGCATGATGCGCCCGCGGATTTTCACGCAGGCCGGGGCGCAATGATA
CGTATGGTCTTTCCCGAGGATCCCCCCATTCCATCCGATGCGGATTCGGGAAATGACGAAAAGCACACAG
CTGGACAGGTGATTTG
Protein Sequence 
>gi|17987150|ref|NP_539784.1| nitrogen regulation protein NTRY [Brucella melitensis bv. 1 str. 16M] MNGTRQSSQDEGQGEGRRLLALPGIITVVSALVTASFSFAILIGITPITPDRTVTLALVIINVALILFLILLICREVYRIITARRLGKAASRLHVRIVALFSLIAAIPAIVVAIVASVTLNLGLDRWFDQNTRDIISSSQNFYTAYLQETALNLQSTSYSMLQDLDAQRAIYSLDRNGFIQLMTLQVRGRALLGAFLVRDNGDVVVQSDTGMESHLPPPTKDSLEKAPDGKPVIIPPGNTNFVGALIKMREIPDMYLYTVRSVPPQILDAINLMNANARRYQEMDANRIPTQIAFALLYFGLTLIVLLSAIWTGIAVADRLVRPIRLLIGASDDVAAGNLDVSVPVRSSDGDVGALSGTFNNMVAELKSQRNELISAKDQIDERRRFSEAVLSGVTAGVIGIENDGSISILNRSAEHMFGVTSEDAVGKSLTSIAPEVGQAFEVARATGRTVHREQVSMARGGGSRSFNVQVTVEDAESEDHSYVVTVDDITDLVQAQRSSAWADVARRIAHEIKNPLTPIQLSAERIRRRYGKVITEDREVFDQCTDTIIRQVGDIGRMVDEFSAFARMPQPEMRHMDLREALREASFLIEVSRSDIHFDNDFGSEKLIGSFDSRLIGQAFGNVIKNASEAIDAVAKEERGEGHIRIHAYRADGQLVVDVIDNGKGLPGDDRQKLLEPYMTTREKGTGLGLAIVRKIVEDHGGNLELHDAPADFHAGRGAMIRMVFPEDPPIPSDADSGNDEKHTAGQVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The NtrY protein is a sensor of an ntr-related regulon which may be part of the glnALG operon. This mutant has a weakly attenuated phenotype (reduction of 1.2 log units versus the wild type at 48 h postinfection) which could be explained by a pleiotropic effect on the ntr regulon, since the ntrC mutant did not show such a phenotype (Foulongne et al., 2000).
COG COG5000T, under T: Signal transduction mechanisms
References
Foulongne et al., 2000: Foulongne V, Bourg G, Cazevieille C, Michaux-Charachon S, O'Callaghan D. Identification of Brucella suis genes affecting intracellular survival in an in vitro human macrophage infection model by signature-tagged transposon mutagenesis. Infection and immunity. 2000; 68(3); 1297-1303. [PubMed: 10678941].