Victors

thrA
Victor ID	1242
Gene Name	thrA
Sequence Strain (Species/Organism)	Brucella melitensis bv. 1 str. 16M
NCBI Gene ID	1196436
NCBI Protein GI	17987008
Locus Tag	BMEI0725
Genbank Accession	AE008917
Protein Accession	NP_539642
Other Database IDs	UniProtKB-ID: D0B8Z0_BRUME UniRef100: UniRef100_D0B8Z0 UniRef90: UniRef90_A5VR43 UniRef50: UniRef50_C6AWW2 UniParc: UPI0000057DBF EMBL: GG703780 EMBL-CDS: EEW86646.1 RefSeq_NT: NC_003317.1 OMA: LGIVNGT
Taxonomy ID	224914
Chromosome No	I
Gene Starting Position	750768
Gene Ending Position	752087
Gene Strand (Orientation)	+
Protein Name	homoserine dehydrogenase
Protein pI	6.52
Protein Weight	43536.29
Protein Length	439
Protein Note	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
DNA Sequence	>gi\|17986284:750768-752087 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence AATGAGTGATGCATTGCGGATCGGTGTTGCCGGCCTGGGCACCGTTGGTGCTTCGGTGTTACGTATTCTG CGTGACAAGTCCGAGATGCTCACGCGCCAGTGCGGCAAGCCTGTAACGGTTACGGCGGTTAGCGCCCGTG ACCGCAATCGGGATCGCGGCATCGACCTTTCAGGCATTGCATGGTTCGATGACCCGGTGGAACTTGCCAA ATCTGCCGAGATCGATCTTTTTATCGAGCTGATCGGCGGCGAGGATGGCCCGGCCAAGGCGTCTGTGGAA GCGGCCTTGCGCGCTGGCCGCCATGTGGTCACGGCCAACAAGGCGCTGCTTGCGCGCCATGGCGTTGCAC TTGCCAGGATCGCCGAGGAGAAGGGCGTCCTGCTCAATTTTGAAGCGGCTGTCGCAGGCGGCATTCCCGT CATCAAGGCCATGCGTGAATCGCTGACCGGAAACACGGTTTCGCGCGTTTACGGCATCATGAACGGCACC TGTAACTATATCCTGACCCGGATGTGGGAAGAGGGGATTTCGTTTGAATCCTGCCTCAAGGATGCGCAGC GCCTGGGATATGCCGAGGCCGACCCGACCTTCGATATTGAAGGCAACGACACAGCGCACAAGCTGGCGCT TCTCACCAGTCTTGCCTTCGGCACGCAGATCGCCGCCGACGATATCTATCTGGAAGGTATCAGCAATATT TCGCTGGCTGACATTCGTGCCGCTGACGAACTTGGCTACCGCATCAAGCTTCTTGGTGTTGCACAGAAGA CCGATACCGGCATCGAACAGCGCGTACATCCGACCATGGTGCCAACCTCTTCGGTTATTGCGCAGGTTCA TGGTGTGACCAATGCTGTCGCCATCGAGACCGATCTTTTGGGTGAGCTTCTGCTTTCAGGTCCCGGTGCG GGTGGCAATGCCACGGCTTCGGCGGTGATCGGCGATGTGGCCGATATCGCCAAGAGCCGTCCGGGTTTCC AGCATGGGCCGGTATTCGGCACGCCTGCCAAGGCCTTGCAGCCCTATAATCGCGCCAAGATGCGCAAACA TGCGGGCGGCTATTTCATTCGCCTCACGGTACATGACCGCATTGGCGCTTTTGCGGCGATTGCCCGGCGC ATGGCGGAAAACGACATTTCGCTGGAATCGATCGTGCAGCGCCCGCCCATGGATGACGCGCCGCGCGAAG GTGTCAAGACGGTGATTCTGGTGACACATGAGACAACCGAATCTGCGGTCAAGAAGGCTCTGGAAGCCAT TCTGAAAGACGATCATCTGGTGGACAAGCCGCAGATGATCCGCATTGAACGCGCTGGCTG
Protein Sequence	>gi\|17987008\|ref\|NP_539642.1\| homoserine dehydrogenase [Brucella melitensis bv. 1 str. 16M] MSDALRIGVAGLGTVGASVLRILRDKSEMLTRQCGKPVTVTAVSARDRNRDRGIDLSGIAWFDDPVELAK SAEIDLFIELIGGEDGPAKASVEAALRAGRHVVTANKALLARHGVALARIAEEKGVLLNFEAAVAGGIPV IKAMRESLTGNTVSRVYGIMNGTCNYILTRMWEEGISFESCLKDAQRLGYAEADPTFDIEGNDTAHKLAL LTSLAFGTQIAADDIYLEGISNISLADIRAADELGYRIKLLGVAQKTDTGIEQRVHPTMVPTSSVIAQVH GVTNAVAIETDLLGELLLSGPGAGGNATASAVIGDVADIAKSRPGFQHGPVFGTPAKALQPYNRAKMRKH AGGYFIRLTVHDRIGAFAAIARRMAENDISLESIVQRPPMDDAPREGVKTVILVTHETTESAVKKALEAI LKDDHLVDKPQMIRIERAG
Molecule Role	Virulence factor
Molecule Role Annotation	FUNCTIONAL GROUP: a.a. metabolism, Synthesis (Delrue et al., 2004). FUNCTION: Lys. synthesis (Delrue et al., 2004). MUTATION: Attenuated in Macrophages (Delrue et al., 2004).
COG	COG0460E, under E: Amino acid transport and metabolism
References	*Delrue et al., 2004:* Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].


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thrA