Victors

ilvI
Victor ID	1237
Gene Name	ilvI
Sequence Strain (Species/Organism)	Brucella melitensis bv. 1 str. 16M
NCBI Gene ID	1196328
NCBI Protein GI	17986900
Locus Tag	BMEI0617
Genbank Accession	HD006899
Protein Accession	NP_539534
Other Database IDs	UniProtKB-ID: D0B8N5_BRUME UniRef100: UniRef100_D0B8N5 UniRef90: UniRef90_A9M647 UniRef50: UniRef50_C7JD40 UniParc: UPI0000057D53 EMBL: GG703780 EMBL-CDS: EEW86541.1 RefSeq_NT: NC_003317.1 OMA: KPQYAVQ
Taxonomy ID	224914
Chromosome No	I
Gene Starting Position	643337
Gene Ending Position	645160
Gene Strand (Orientation)	+
Protein Name	acetolactate synthase 3 catalytic subunit
Protein pI	5.9
Protein Weight	62136.67
Protein Length	607
Protein Note	catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive
DNA Sequence	>gi\|17986284:643337-645160 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence GATGAATGCAGGTAAACATGAGGCGGAAGCAAACGCCGGGCAAGCGCAGGACGCAGGCCATCCACGCGAA ATGACCGGCGCAGAAATGGTTATCCAGGCGCTGATCGATCAGGGTGTGGAAAGCATTTTCGGCTATCCCG GCGGCGCGGTGCTTCCGATTTATGACGGGCTGTTTCAGCAGGATCAAATCCAGCACGTTCTGGTTCGCCA TGAGCAGGGTGCAGGCCATGCAGCGGAAGGCTATGCGCGCTCGACGGGTAAAGTCGGCGTCATGCTCGTC ACTTCGGGGCCGGGTGCAACCAATGCCGTGACGCCGTTGCAGGATGCCTTGATGGATTCCATCCCGCTGG TCTGCATTTCCGGTCAGGTTCCCACGACGCTGATCGGTTCCGATGCGTTTCAGGAATGCGATACGATTGG CATCACGCGCCCCTGCACCAAGCACAACTGGCTGGTAAAGGACGTCAACGACCTGTCGCGCGTCCTGCAT GAAGCTTTCCATGTCGCATCCACCGGCCGTCCCGGCCCCGTCGTCGTCGATATTCCGAAGGATATTCAGT TCGCCAAGGGCATCTATACGCCGCCGGAAACTGCACCGCGCACAAGTTACCGTCCAGTTCTCGACGGCAA TGCCGAGGCTATTTCCGAGGCTGTCCGTCTGCTCGCCAATGCCAGAAAGCCGGTTATTTATTCGGGCGGC GGCGTGATCAATTCCGGCCCCGCGGCTTCCCGTCTGCTGCGTGAGCTGGTCGAGATCAGCAATTTCCCGA TCACCTCCACGCTGATGGGGCTTGGCGCCTATCCCGCCTCCGGCAAGAACTGGCTCGGTATGCTGGGCAT GCACGGCACCTATGAAGCCAACATGACCATGCATGATTGCGATGTCATGCTGTGCGTCGGTGCGCGTTTC GACGACCGCATCACCGGCCGCCTCAACGCTTTCTCGCCGAATTCCAAGAAAATTCATATCGATATCGATC CGTCGTCGATCAACAAGAACGTTCGGGTCGATGTGCCGATCATCGGCGATGTCGCGCATGTGCTGGAGGA TATCGTCCGCCAGTTTCGTGCTTTCGACCGCAAGCCGGACAGGCAGGCATTGACCGAATGGTGGGGGCAG ATCGACCGTTGGCGCGCGCGCAATTCGCTGGCCTATACGCCGAACAAAGACGTCATCATGCCGCAATATG CCATCGAGCGGCTTTATGAACTGACCAGGAACCGCAACACCTATATCACCACCGAGGTGGGCCAGCACCA GATGTGGGCGGCGCAATTCTTCGGCTTTGAACAGCCGAACCGTTGGCTGACTTCCGGCGGCCTTGGCACC ATGGGCTATGGTCTGCCTGCGGCGCTGGGCGTGCAGATTGCACATCCGGATGCGCTGGTTATCGATATTG CAGGCGATGCCTCGATCCAGATGTGTATCCAGGAAATGTCGGCAGCAATCCAGCATAATGCGCCGATCAA GATTTTCATCCTGAACAACCAGTATATGGGCATGGTGCGCCAGTGGCAGCAATTGCTGCATGGCAACCGC CTGTCGCATTCCTACACGGAAGCGATGCCCGATTTCGTGAAACTTGCGGAAGCATACGGCGCGCACGGCA TTCGCTGCGAGAAGCCGGGCGATCTCGATGCCGCCATTCAGGAGATGATCGATATCGACAAGCCGGTCAT TTTCGATTGCCGCGTGGCAAACCTTGCCAACTGCTTCCCGATGATCCCGTCGGGCAAGGCGCATAATGAA ATGCTGTTGCCGGACGAAGCGACAGATGAGGCCGTCGCCAATGCCATTGATGCCAAGGGCCGCGCGCTCG TCTG
Protein Sequence	>gi\|17986900\|ref\|NP_539534.1\| acetolactate synthase 3 catalytic subunit [Brucella melitensis bv. 1 str. 16M] MNAGKHEAEANAGQAQDAGHPREMTGAEMVIQALIDQGVESIFGYPGGAVLPIYDGLFQQDQIQHVLVRH EQGAGHAAEGYARSTGKVGVMLVTSGPGATNAVTPLQDALMDSIPLVCISGQVPTTLIGSDAFQECDTIG ITRPCTKHNWLVKDVNDLSRVLHEAFHVASTGRPGPVVVDIPKDIQFAKGIYTPPETAPRTSYRPVLDGN AEAISEAVRLLANARKPVIYSGGGVINSGPAASRLLRELVEISNFPITSTLMGLGAYPASGKNWLGMLGM HGTYEANMTMHDCDVMLCVGARFDDRITGRLNAFSPNSKKIHIDIDPSSINKNVRVDVPIIGDVAHVLED IVRQFRAFDRKPDRQALTEWWGQIDRWRARNSLAYTPNKDVIMPQYAIERLYELTRNRNTYITTEVGQHQ MWAAQFFGFEQPNRWLTSGGLGTMGYGLPAALGVQIAHPDALVIDIAGDASIQMCIQEMSAAIQHNAPIK IFILNNQYMGMVRQWQQLLHGNRLSHSYTEAMPDFVKLAEAYGAHGIRCEKPGDLDAAIQEMIDIDKPVI FDCRVANLANCFPMIPSGKAHNEMLLPDEATDEAVANAIDAKGRALV
Molecule Role	Virulence factor
Molecule Role Annotation	FUNCTIONAL GROUP: a.a. metabolism, Synthesis (Delrue et al., 2004). FUNCTION: Val. Leu., Isoleu. Synthesis (Delrue et al., 2004). MUTATION: Attenuated in Macrophages, HeLa (Delrue et al., 2004).
COG	COG0028EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References	*Delrue et al., 2004:* Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].


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ilvI