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serB from Brucella melitensis bv. 1 str. 16M

Victor ID 1235
Gene Name serB from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1196326
NCBI Protein GI 17986898
Locus Tag BMEI0615
Protein Accession NP_539532.1
Other Database IDs UniProtKB-ID: Q8YI30_BRUME
UniRef100: UniRef100_D0B8N3
UniRef90: UniRef90_C0RE31
UniRef50: UniRef50_C0RE31
UniParc: UPI0000057D51
EMBL: AE008917
EMBL-CDS: AAL51796.1
RefSeq_NT: NC_003317.1
HSSP: P78330
GenomeReviews: AE008917_GR
KEGG: bme:BMEI0615
NMPDR: fig|224914.1.peg.614
HOGENOM: HBG645339
OMA: HVAAITE
ProtClustDB: CLSK898171
BioCyc: BMEL224914:BMEI0615-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 641241
Gene Ending Position 642149
Gene Strand (Orientation) -
Protein Name PHOSPHOSERINE PHOSPHATASE
DNA Sequence 
>gi|17986284:641241-642149 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
CTTATTGGACGAAATCTGCCTTTCGGTAGCCCTGGATATAGAGAAGGGCGGTGAGGTCGCCATGGTCGAT
GCGCATTTTTGCCTGTGCGGCCACGGCGGGCTTGGCGTGAAGCGCCACGCCGGTCCCGGCAAGCTGGATC
ATGCCCAGATCGTTCGCGCCATCGCCGACTGCGATAGCGTCTTCGGGGGTGAGGCCAACGCGTTCGGCGA
TCTCGACCAGTTTTTCGACCTTGGCTTCGCGGCCTAATATAGGCTCAGCGACGGTACCCGTCAGGCGGGT
TCCGTCATCGATCAGGCGATTGGCGCGTTCCTCATTGAAGCCGATCATTTCGGCAATGCGGCGGGTAAAC
GAGGTGAAGCCGCCGGAAACGAGTGCTGTATAAGCGCCGTGCTTGCGCATGGTGCGCACCAGTTGCGGCC
CGCCGGGGGTGAGGGTGATGCGGGTGGAGATAACCTTGTCGATCACCGAAAGCGGCAATCCCTTCAAAAG
CGCGACGCGCTCGCGAAGTGCCGGCTCGAAGGCAATCTCGCCATTCATTGCGCGCGCGGTGATCGCGGCC
ACATGGTCGCGCAGGCCCGCTTCTTCCGCCAGTTCATCGATACATTCCTGCCCGATCATGGTGGAATCCA
TATCGGCAATCAAAATTTTCTTGCGCCGGCGTTCCTGTTCCTGCACCACCACGTCGATAGGCGCGCCGTC
AAGGGTGGCGCGCAATGATGCATCCGCCTCACTTGCCTCCATGCCAAGGGGAAGGGGAATGTCGCAGGCA
ATATCATCTGCCAGCCAGTAAAGTCCGGTTGCATTCACTGCCGCCGAGGCTTTAATGCCGAGCGAAGGGG
CAAGCGCGGCTTTTGCCGGGTTGGCGATCAGGGTAGCGACGAGAGAAACCTGCTGCGACATGGAGAGCA
Protein Sequence 
>gi|17986898|ref|NP_539532.1| phosphoserine phosphatase [Brucella melitensis bv. 1 str. 16M] MLSMSQQVSLVATLIANPAKAALAPSLGIKASAAVNATGLYWLADDIACDIPLPLGMEASEADASLRATLDGAPIDVVVQEQERRRKKILIADMDSTMIGQECIDELAEEAGLRDHVAAITARAMNGEIAFEPALRERVALLKGLPLSVIDKVISTRITLTPGGPQLVRTMRKHGAYTALVSGGFTSFTRRIAEMIGFNEERANRLIDDGTRLTGTVAEPILGREAKVEKLVEIAERVGLTPEDAIAVGDGANDLGMIQLAGTGVALHAKPAVAAQAKMRIDHGDLTALLYIQGYRKADFVQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis serB gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0560E, under E: Amino acid transport and metabolism
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].