Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

aspC from Brucella melitensis bv. 1 str. 16M

Victor ID 1231
Gene Name aspC from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1196227
NCBI Protein GI 17986799
Locus Tag BMEI0516
Protein Accession NP_539433.1
Other Database IDs UniProtKB-ID: Q8YIC8_BRUME
UniRef100: UniRef100_D0B9T8
UniRef90: UniRef90_D0B9T8
UniRef50: UniRef50_Q1RGV0
UniParc: UPI0000057CEF
EMBL: AE008917
EMBL-CDS: AAL51697.1
RefSeq_NT: NC_003317.1
HSSP: Q56232
GenomeReviews: AE008917_GR
KEGG: bme:BMEI0516
NMPDR: fig|224914.1.peg.515
HOGENOM: HBG645860
OMA: IGKTAPS
ProtClustDB: PRK05764
BioCyc: BMEL224914:BMEI0516-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 535209
Gene Ending Position 536474
Gene Strand (Orientation) -
Protein Name aspartate aminotransferase
DNA Sequence 
>gi|17986284:535209-536474 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
ATCAGCGCAGGCTGGCGCAGAAACGCTGGATGCGTATGCAGGCTTTTTCCAGCAGCTCATCCGAGGTTGC
ATAGGAAATGCGGAAGTTCGGGCCGAGGCCGAATGCCGAACCATGAACAACCGCCACGCCTTCGGTTTCC
AGAAGTTCCGTCACAAAATCTTTGTCGGTTTCGATGACTTTGCCCGCTTCGGTCTTCTTGCCGATCAGCC
CTGCGCAGGACGGATAGACATAGAACGCGCCTTCCGGCGTCGGGCACTGGAGGCCGGTTGCCTGGTTGAG
CATGGAAACGACCAGATCGCGGCGGGCCTGGAAGATTTTCTTGTTCGCGGGGATGAAATCCTGCGTGCCG
TTCAGTGCTTCGACCGCTGCCCACTGAGCAATCGAGCAGGCGCCGGAGGTCTGCTGCCCCTGAATCATGT
CCATGGCCTTGATGAGCTCGATTGGACCGGCGGCATAGCCGATGCGCCAGCCGGTCATGGCATAGGCCTT
GGAAACGCCGTTCATGGTGAGCGTACGGTCATAGAGCGAGGGTTCCACCTGAGCAGGCGTCGTGAAGACG
AAATCGCCATAGACCAGATGCTCATACATGTCGTCGGTCAAGATCCAGACATGCGGATGGCGCACGAGAA
CGTCGGTCAGCGACTTCAGTTCGGCTTGCGTATAGGCCGCGCCGGTCGGGTTGGAGGGCGAGTTGAAGAT
GAGCCACTTGGTCTTCGGTGTGATCGCCTTTTCGAGATCGGCAGCGGTCAGCTTGAAATTGTCTTCAATC
TTCGTGTCGACGAAAACCGGGGTGCCGCCGTTGATGGCCACCATTTCTGGGTAGCTGACCCAATAGGGGG
CGGCAATGATGACTTCGTCGCCGGGGTTCAGCGTGGCCATGAAGGCGTTGAACAAAATCTGCTTGCCGCC
GGTGCCGACGATGGTTTGTTCCGGCTTGTAGTCGAGGCCGTTTTCACGCTTGAACTTGGAGACGATGGCC
TGGCGCAGTTGCGGGATGCCGGATACGGGCGTGTACTTTGTTTCACCGCGATTGATCGCGGCAATGGCCG
CCTGCTTGATATTTTCAGGCGTGTCGAAATCCGGCTCACCTGCGCCCAGGACGATCACGTCCTTGCCTTT
TGCTTTCAGTTCACGTGCTTTCTGGCTGACAGCGATGGTCGCAGATGGCTTTACACGGGAAAGGGCGTCG
GCGAGAAATGCCATGATAGATCTCCATAGATGGCAGGCTCTGTTAACCGTCACCGGGCGTGGTCCGGTTT
TGCGCA
Protein Sequence 
>gi|17986799|ref|NP_539433.1| aspartate aminotransferase [Brucella melitensis bv. 1 str. 16M] MRKTGPRPVTVNRACHLWRSIMAFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRGETKYTPVSGIPQLRQAIVSKFKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIAAPYWVSYPEMVAINGGTPVFVDTKIEDNFKLTAADLEKAITPKTKWLIFNSPSNPTGAAYTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKAYAMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQARRDLVVSMLNQATGLQCPTPEGAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGVAVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aspC encodes for an aminotransferase. B.abortus aspC mutant obtained from randomized miniTn5Km2 transposon mutagenesis showed decreased intracellular survival inside HeLa cells. So B. abortus aspC gene is essential for HeLa cell intracellular growth (Kim et al., 2003).
COG COG0436E, under E: Amino acid transport and metabolism
References
Kim et al., 2003: Kim S, Watarai M, Kondo Y, Erdenebaatar J, Makino S, Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infection and immunity. 2003; 71(6); 3020-3027. [PubMed: 12761078].