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lpsB

Victor ID 1228
Gene Name lpsB
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1196220
NCBI Protein GI 17986792
Locus Tag BMEI0509
Protein Accession NP_539426.1
Other Database IDs UniProtKB-ID: D0B9T1_BRUME
UniRef100: UniRef100_D0B9T1
UniRef90: UniRef90_D0B9T1
UniRef50: UniRef50_B9JYZ8
UniParc: UPI0000057CE8
EMBL: GG703780
EMBL-CDS: EEW86437.1
RefSeq_NT: NC_003317.1
OMA: FHPPETA
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 529269
Gene Ending Position 530333
Gene Strand (Orientation) +
Protein Name LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS MANNOSYLTRANSFERASE LPCC
DNA Sequence 
>gi|17986284:529269-530333 Brucella melitensis bv. 1 str. 16M chromosome chromosome I, complete sequence
CGTGACTTTATCAGGGCAAGTTCCGGTTCGGGAAGTTGAGGTCGTTGCACCCAACTTCAAGCGCCGCCTT
TCCGGCGTGACCTCGACGATTGTTCAGCTCATTCCATTGCAGCGCGCAATGGGGCTGAAAATTGCCACTA
TGGGGCCGGGCCTGCCTGACACTCTCCCGCATCTTGGATGGAGCGCGTTGCCCTCCTTCTGGTCGCGACC
TAAAACCAGACGGTTTCGCATCTGGCATGCGCGCCGCAACATTGAAATGCTTGCCGGAATTTTCATGCGG
GATGTCCTGCGCATGAAACTGCGGCTCGTTTTTACCTCGGCCGCCCAGCGCCATCACAAACCTTTCACTA
AATGGCTCATCCGCCGCATGAATGCGGTGATCGCGACAAGTGTGCGTTCGGGAAGTTTTCTCGAAGTCCC
GCATCAGGTCATCATGCATGGTGTCGATCTGGAACGGTTTCACCCGCCTCTTGCGGAGGACGATGATTTT
TCCGCTTCCGGCCTGCCGGGTAAATATGCCGTAGGGTGTTTTGGACGGGTTCGGCCTTCAAAAGGAACGG
ACCTTTTCGTTGATGCGATGATCGCGCTCCTGCCGAAATATCCTGACTGGACGGCCATTGTCACGGGGCG
CACAACCGCCGAATATCAGGCCTTTGAAGCCGAGCTGCGCACCAGGATTGCGGCAGCCGGTTTGCAGGAC
CGTATTCTTATTCTGGGCGAAGTGCCGGACGTGCGCGTCTGGTATCGCCGGCTCACGCTTTACGTCGCGC
CTTCCCGCAATGAAGGCTTTGGCCTGACGCCGCTTGAAGCCATGGCCTCGAAAACAGCCGTCGTTGCCAG
TGATGCCGGGGCTTATGCGGAAATGGTCGTTGAGGATACGGGCCGCTTTGTGCCAGCCGGTGACGGGCGC
GCATTGACGAACGCCATCGAACCTTATCTGGCCGATCCGGCCATGACAAAACGCTGCGGCGAAAATGCTC
TGGCGCATGTTCGCGAAGCCTTTCCGCTCCAAAAGGAAGCGGCTGCTATCAGCAGCGTTTATGAACAGGT
TTTCGCAGGAAGATA
Protein Sequence 
>gi|17986792|ref|NP_539426.1| lipopolysaccharide core biosynthesis mannosyltransferase LPCC [Brucella melitensis bv. 1 str. 16M] MTLSGQVPVREVEVVAPNFKRRLSGVTSTIVQLIPLQRAMGLKIATMGPGLPDTLPHLGWSALPSFWSRPKTRRFRIWHARRNIEMLAGIFMRDVLRMKLRLVFTSAAQRHHKPFTKWLIRRMNAVIATSVRSGSFLEVPHQVIMHGVDLERFHPPLAEDDDFSASGLPGKYAVGCFGRVRPSKGTDLFVDAMIALLPKYPDWTAIVTGRTTAEYQAFEAELRTRIAAAGLQDRILILGEVPDVRVWYRRLTLYVAPSRNEGFGLTPLEAMASKTAVVASDAGAYAEMVVEDTGRFVPAGDGRALTNAIEPYLADPAMTKRCGENALAHVREAFPLQKEAAAISSVYEQVFAGR
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: "Classical virulence factors", Envelope molecules, Lipopolysaccharide (Delrue et al., 2004).

FUNCTION: Core synthesis (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages (Delrue et al., 2004).
COG COG0438M, under M: Cell wall/membrane/envelope biogenesis
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].