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lysA from Brucella melitensis bv. 1 str. 16M

Victor ID 1203
Gene Name lysA from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1195796
NCBI Protein GI 17986368
Locus Tag BMEI0084
Protein Accession NP_539002.1
Other Database IDs UniProtKB-ID: Q8YJJ9_BRUME
UniRef100: UniRef100_Q8YJJ9
UniRef90: UniRef90_A5VSV3
UniRef50: UniRef50_Q9KVL7
UniParc: UPI0000057B41
EMBL: AE008917
EMBL-CDS: AAL51266.1
RefSeq_NT: NC_003317.1
HSSP: P31848
GenomeReviews: AE008917_GR
KEGG: bme:BMEI0084
NMPDR: fig|224914.1.peg.84
HOGENOM: HBG672375
OMA: SIAGKCC
ProtClustDB: CLSK863778
BioCyc: BMEL224914:BMEI0084-MONOMER
Taxonomy ID 224914
Chromosome No I
Gene Starting Position 82964
Gene Ending Position 84229
Gene Strand (Orientation) -
Protein Name DIAMINOPIMELATE DECARBOXYLASE
Protein Sequence 
>gi|17986368|ref|NP_539002.1| diaminopimelate decarboxylase [Brucella melitensis bv. 1 str. 16M] MNHFEYRNGVLHAENVSLPEIAKAVGTPFYVYSRATIERHFRVFHDAFADMDTLVTYALKANSNQAVLTALAKLGAGADTVSQGEIRRALAAGIPANRIVFSGVGKTPREMDFALEAGIYCFNVESEPELEILSARAVAAGKVAPVSLRINPDVDAKTHAKISTGKSENKFGIPRDKARAAYARAASLPGLNVVGIDMHIGSQIIDLEPFDNAFALMAELVKELQADGHNIRHVDVGGGLGIPYRTPNTPPPPPVAYAQIVAKHIKPLGLKTVFEPGRLIVGNAGLLVTEVIFVKEGDAKNFVIVDAAMNDLIRPTLYDAFHDIRPVIMPNDNAPRIRADFVGPVCETGDYLGLDREVAKPAPGDLIAICTTGAYGAVLSSTYNSRLLIPEVLGDGERYHVVRPRRTYEELLALDSVPDWL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis lysA gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0019E, under E: Amino acid transport and metabolism
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].