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spaR from Salmonella enterica subsp. enterica serovar Typhi str. CT18

Victor ID 1194
Gene Name spaR from Salmonella enterica subsp. enterica serovar Typhi str. CT18
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhi str. CT18
NCBI Gene ID 1249317
NCBI Protein GI 16761665
Locus Tag STY3011
Protein Accession NP_457282.1
Other Database IDs UniProtKB-ID: Q8Z491_SALTI
UniRef100: UniRef100_Q8Z491
UniRef90: UniRef90_P40701
UniRef50: UniRef50_P40701
UniParc: UPI000005A36F
EMBL: AE014613
EMBL: AL627276
EMBL-CDS: AAO70351.1
EMBL-CDS: CAD05995.1
RefSeq_NT: NC_003198.1
RefSeq_NT: NC_004631.1
GenomeReviews: AE014613_GR
GenomeReviews: AL513382_GR
KEGG: stt:t2790
KEGG: sty:STY3011
HOGENOM: HBG474088
OMA: YTAFISS
ProtClustDB: CLSK894370
BioCyc: SENT209261:T2790-MONOMER
BioCyc: SENT220341:STY3011-MONOMER
Taxonomy ID 220341
Gene Starting Position 2884589
Gene Ending Position 2885380
Gene Strand (Orientation) -
Protein Name secretory protein (associated with virulence)
DNA Sequence 
>gi|16758993:2884589-2885380 Salmonella enterica subsp. enterica serovar Typhi str. CT18 chromosome, complete genome
TTTATTCGAGGACATGCGTCGCCCCTCGCTCGTAAAACCAACTGCTTAACCCTGTGGCCTGGAAAGAGAG
TCGCGGTACATTGTCCGGTAGTACCGGAGAGAAATAAAGCAGCATAATTAAAACGGCAATGCCGCTTTTT
ACCGTCAGTGAAATCGCAAAAGCGTTCATTTGCGGAGCAAAGCGCGACAATAAACCCAGGAATACTTCTG
ACAGCAACAGCACTAATACCACCGGACTGGCCAGAACCAAGGCGTTTTGAGCCACCTGATTAATAAACGT
TAATAGCGGCGGTAATGAAGGCGTGCACTCGTTCATCGGATCGCATAGCTGATAGCTTTTATTTAACACG
TCAACCATCGTGACCAGACCGCCGTTTTGTAAATAAACGACAGCGGCAAACATATTCAGGAAATTAGCCA
TTTCCGAGGTATCAATACCGTTTGCCGGATCGATACTGCTACTTAGCGTTGCCCCTCGCTGGTTATCGAT
AATACAACCCAGCGCATGCATAACCCAAAAAGGCCATGACAGCAGACAGCCCAGCATGACGCCTACCGCC
GCTTCTTGCAGAACTAACGGGATCATCGCCACCGATAAAAACGGCGGCGCCTCGTTCAATGCATGCGGCC
ATACTCCCAATGCCACCAGGATGATAATGGCGTTTCTCGGCGCGCCGCTTAATACCCCGCTATTCAAAAA
CGGCAGGAAGAAAAAAATCGGCGCTACGCGAGCAAACCCTAGTGCCGCAGACGCAACCAGGTGATGAATT
TCAAAGTACAACGCGTAAAGCA
Protein Sequence 
>gi|16761665|ref|NP_457282.1| secretory protein [Salmonella enterica subsp. enterica serovar Typhi str. CT18] MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPMNECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVPRLSFQATGLSSWFYERGATHVLE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spaR mutant is severely impaired in entry to Henle-407 cells (Collazo and Galán, 1996).
COG COG4791U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Collazo and Galán, 1996: Collazo CM, Galán JE. Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium. Infection and immunity. 1996; 64(9); 3524-3531. [PubMed: 8751894].