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sigD from Salmonella enterica subsp. enterica serovar Typhi str. CT18

Victor ID 1181
Gene Name sigD from Salmonella enterica subsp. enterica serovar Typhi str. CT18
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhi str. CT18
NCBI Gene ID 1247536
NCBI Protein GI 16759971
Locus Tag STY1121
Protein Accession NP_455588.1
Other Database IDs UniProtKB-ID: SOPB_SALTI
UniRef100: UniRef100_Q8Z7R1
UniRef90: UniRef90_O34105
UniRef50: UniRef50_O30916
UniParc: UPI0000059FFD
EMBL: AL627269
EMBL: AE014613
EMBL: AF213333
EMBL-CDS: CAD08217.1
EMBL-CDS: AAO69449.1
EMBL-CDS: AAF21055.1
RefSeq_NT: NC_003198.1
RefSeq_NT: NC_004631.1
GenomeReviews: AE014613_GR
GenomeReviews: AL513382_GR
KEGG: stt:t1828
KEGG: sty:STY1121
HOGENOM: HBG671713
OMA: CWNCKSG
ProtClustDB: CLSK862850
BioCyc: SENT209261:T1828-MONOMER
BioCyc: SENT220341:STY1119-MONOMER
Taxonomy ID 220341
Gene Starting Position 1088686
Gene Ending Position 1090371
Gene Strand (Orientation) -
Protein Name cell invasion protein
DNA Sequence 
>gi|16758993:1088686-1090371 Salmonella enterica subsp. enterica serovar Typhi str. CT18 chromosome, complete genome
CTCAAGATGTGATTAATGAAGAAATACCTTTTACTGACTGCCAAATATTTTCATCCCCAACTCGTTTTTG
ATAGGAAAGATTGAGCACCTCTGGCGATAAATTTTTCATTACTTTGTTTCCCGCCCCGCCCGTATTTTGT
TTCTGAATCTCCAGGTTACCGCTATTCAGTAATACTTTTTGGAAAATTTTCTGTCCACCGCTATCCGGAA
GACTACCAGGCGCACTTAACATATGGGTCTGATGGAAAGAAATGAGCTCTCGCTTGATTTCTGAATCCAT
CATCCCTGTACGATCTTTGCCGCTTTTACAATTCCAGGCGGGCACCGCGTCAATTTCATGGGCTAACATG
GCAAGGCGTTGTGCGAGTTTATAGGGTTCGCCGCCATCTTTATGATGTTGGTTATTTTTCCAGATATCCT
TAATCTGGCGCGCTAATGTATTGACGACCTCATAATTATCCGGGTATTGCGCCAGCCATTCGCCAACCCA
GCCACCTGGTCTGGCTTCAGGGCGTAAATCATTGCCTAATAACTGATGTAGCGCTTCGGCATTATAGCTA
TCTGATGCTTTAAGGCCAAAGCCGAGCTTGAGCGCCAGCTCATTAACACCCACATTAAATGCGGCGACGT
CCGGTTTTATTTTTACCGTCTGTAGATCGCCATCTTTATTGCGGATTTTTAAATGAATCATTTTTCCCGG
CTGGGTCAACGATTGCCATGCGCGCATTTGATCCTCGACCATAGTTCCCTCTTTGCCGAAAATATTCGAC
GCGGTGAGTAACCCGACGGATACCAGTTTCAGGCTTACCGCTTCGCCCTCTAAGGCTCTGTTAAGCAACT
CAGGTTTACTAAAAAGTGCCGCAGCTAATACTTCTTTGGCTTTGTTTTCAGCGCCGGCCTGACGCAGAAG
CGGATCTTTTTCATGATAGGGGGAAAGCACACCATGACGTATCCCGCAAAAAAGCGTTTTATCTTTACCG
TCCTCATGCACACTCACCGTGGACATCCACAAATTATTGGCGTGATGAATATTCTTGGTATCCCAACTGC
ATACGCCCTTTCCCTCATAAGCACTGGGAAAGATATCTTTTGCGCCGATTTTCATCTCTGCGGCAGGGAG
CTGCGTGTTGGTATAGTGATGCCCGTTATGCGTGAGTGTATTTTTTATGGTTTGCCAGGGCTGGTTATTG
AGCTGCTTGACCTGAGCATCTCTAAACGCTACTGCCGCAAAGCGATGAGCTTCTTTTGCAGGTAAGCCAT
TTTGCTGCTGAGTGCGTGCTGCAATAAGTTCGATAAGATTTTTCTTCAATGCTTTTGCCGCAGCTTCTTC
TTGTTTTGTTGCTGGCCGGTCCGCTTTAACTTTGGCTAACTCCATTTGGTTTGCCATTGACGTTAGAACC
GGGTCTTGTTTACCCAGAACGGTTGCCGCGACGGTAAGAAGATCGCGCTGTAAGTTATAGAGGTTATGCA
GCGAGTGGTTAGACGTCTTCTGATGCTGTAGATAATTCCCCCATGTCGCGCCAGGTTCTCGCAGGACAAT
AATTTCCGGGCGAGCGTCGGGCGCTTTAGCCGGCGCTTTGCCCTGGCCTGAGAGAATCTGCATTCCGTTG
TATAAGGTTTTTTGTAGGCTTTTAAAAGCCTCCTGGGTTTTTAGTGAAGCTGAGTGATAGAAGCTCTGTA
TTTGCA
Protein Sequence 
>gi|16759971|ref|NP_455588.1| cell invasion protein [Salmonella enterica subsp. enterica serovar Typhi str. CT18] MQIQSFYHSASLKTQEAFKSLQKTLYNGMQILSGQGKAPAKAPDARPEIIVLREPGATWGNYLQHQKTSNHSLHNLYNLQRDLLTVAATVLGKQDPVLTSMANQMELAKVKADRPATKQEEAAAKALKKNLIELIAARTQQQNGLPAKEAHRFAAVAFRDAQVKQLNNQPWQTIKNTLTHNGHHYTNTQLPAAEMKIGAKDIFPSAYEGKGVCSWDTKNIHHANNLWMSTVSVHEDGKDKTLFCGIRHGVLSPYHEKDPLLRQAGAENKAKEVLAAALFSKPELLNRALEGEAVSLKLVSVGLLTASNIFGKEGTMVEDQMRAWQSLTQPGKMIHLKIRNKDGDLQTVKIKPDVAAFNVGVNELALKLGFGLKASDSYNAEALHQLLGNDLRPEARPGGWVGEWLAQYPDNYEVVNTLARQIKDIWKNNQHHKDGGEPYKLAQRLAMLAHEIDAVPAWNCKSGKDRTGMMDSEIKRELISFHQTHMLSAPGSLPDSGGQKIFQKVLLNSGNLEIQKQNTGGAGNKVMKNLSPEVLNLSYQKRVGDENIWQSVKGISSLITS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigD mutant is less invasive than the wild type in both HEp-2 and CHO cell lines (Hong and Miller, 1998).
References
Hong and Miller, 1998: Hong KH, Miller VL. Identification of a novel Salmonella invasion locus homologous to Shigella ipgDE. Journal of bacteriology. 1998; 180(7); 1793-1802. [PubMed: 9537377].