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leuO from Salmonella enterica subsp. enterica serovar Typhi str. CT18

Victor ID 1177
Gene Name leuO from Salmonella enterica subsp. enterica serovar Typhi str. CT18
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhi str. CT18
NCBI Gene ID 1246630
NCBI Protein GI 16759110
Locus Tag STY0134
Protein Accession NP_454727.1
Other Database IDs UniProtKB-ID: Q8Z9H8_SALTI
UniRef100: UniRef100_Q8Z9H8
UniRef90: UniRef90_P46924
UniRef50: UniRef50_P46924
UniParc: UPI00000CDAF3
EMBL: AL627265
EMBL-CDS: CAD01272.1
RefSeq_NT: NC_003198.1
GenomeReviews: AL513382_GR
KEGG: sty:STY0134
HOGENOM: HBG682110
OMA: APNIHLV
ProtClustDB: PRK09508
BioCyc: SENT220341:STY0134-MONOMER
Taxonomy ID 220341
Gene Starting Position 135982
Gene Ending Position 136926
Gene Strand (Orientation) +
Protein Name leucine transcriptional activator
DNA Sequence 
>gi|16758993:135982-136926 Salmonella enterica subsp. enterica serovar Typhi str. CT18 chromosome, complete genome
TATGCCAGAGGTCAAAACCGAAAAGCCGCATCTTTTAGATATGGGCAAACCACAGCTTCGCATGGTTGAT
TTGAACCTATTGACCGTGTTCGATGCGGTAATGCAAGAGCAGAATATTACGCGCGCCGCCCACACGCTGG
GAATGTCGCAGCCTGCGGTCAGTAACGCCGTAGCGCGTCTGAAGGTTATGTTTAATGACGAACTTTTTGT
TCGATATGGACGAGGAATTCAGCCGACTGCCCGTGCATTTCAGTTATTTGGTTCAGTCCGTCAGGCGTTG
CAATTGGTGCAAAATGAATTGCCGGGATCGGGGTTTGAGCCGACCAGCAGCGAACGTGTATTCAATCTTT
GCGTGTGCAGTCCGCTGGATAATATCCTGACGTCACAGATTTATAATCGTGTAGAAAAAATTGCGCCAAA
TATTCATGTCGTTTTTAAAGCGTCGTTGAATCAGAATACTGAGCATCAGTTACGCTATCAGGAAACCGAG
TTCGTTATTAGTTATGAAGAATTCCGTCGTCCTGAGTTTACCAGCGTACCGCTATTTAAAGATGAAATGG
TTTTAGTCGCCAGCCGAAAACACCCGCGTATTAGCGGCCCGCTACTGGAAGGCGATGTTTATAATGAACA
ACATGCGGTTGTTTCTCTCGATCGTTATGCGTCATTTAGTCGGCCGTGGTATGACACGCCGGATAAACAG
TCGAGCGTGGCTTATCAGGGCATGGCGCTTATCAGCGTTCTGAACGTGGTTTCGCAGACGCATTTGGTCG
CTATTGCCCCGTGCTGGCTGGCGGAAGAGTTTGCGGAGTCGCTGGAGCTGCAAATACTGCCGTTGCCTTT
AAAACTGAATAGCCGGACATGCTACCTTTCCTGGCATGAAGCGGCTGGGCGTGATAAAGGGCATCAATGG
ATGGAAGATTTATTAGTCTCTGTTTGTAAGCGATA
Protein Sequence 
>gi|16759110|ref|NP_454727.1| leuABCD operon activator protein [Salmonella enterica subsp. enterica serovar Typhi str. CT18] MPEVKTEKPHLLDMGKPQLRMVDLNLLTVFDAVMQEQNITRAAHTLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPGSGFEPTSSERVFNLCVCSPLDNILTSQIYNRVEKIAPNIHVVFKASLNQNTEHQLRYQETEFVISYEEFRRPEFTSVPLFKDEMVLVASRKHPRISGPLLEGDVYNEQHAVVSLDRYASFSRPWYDTPDKQSSVAYQGMALISVLNVVSQTHLVAIAPCWLAEEFAESLELQILPLPLKLNSRTCYLSWHEAAGRDKGHQWMEDLLVSVCKR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: leuO mutant exhibited wild-type levels of epithelial invasion but highly reduced transepithelial migration of PMN (Tenor et al., 2004).
COG COG0583K, under K: Transcription
References
Tenor et al., 2004: Tenor JL, McCormick BA, Ausubel FM, Aballay A. Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Current biology : CB. 2004; 14(11); 1018-1024. [PubMed: 15182677].