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YPO3398

Victor ID 1172
Gene Name YPO3398
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1176215
NCBI Protein GI 16123547
Locus Tag YPO3398
Protein Accession NP_406860.1
Other Database IDs UniProtKB-ID: GLUQ_YERPE
UniRef100: UniRef100_Q8ZBL1
UniRef90: UniRef90_Q66EG0
UniRef50: UniRef50_C4ZRN7
UniParc: UPI00000CDA17
EMBL: AL590842
EMBL: AE009952
EMBL: AE017042
EMBL-CDS: CAL21987.1
EMBL-CDS: AAM84376.1
EMBL-CDS: AAS60562.1
RefSeq_NT: NC_003143.1
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO3398
KEGG: ypk:y0789
KEGG: ypm:YP_0287
HOGENOM: HBG628189
OMA: IIKRSDG
ProtClustDB: PRK05710
BioCyc: YPES187410:Y0789-MONOMER
BioCyc: YPES214092:YP
Taxonomy ID 214092
Gene Starting Position 3795915
Gene Ending Position 3796880
Gene Strand (Orientation) +
Protein Name glutamyl-Q tRNA(Asp) synthetase
DNA Sequence 
>gi|16120353:3795915-3796880 Yersinia pestis CO92 chromosome, complete genome
TGTGGTTCAACAAGCGGTCATTCAACGATCAGCTAACCAACGAGCAACGAATCAACCAACAGAATATATT
GGCCGTTTTGCACCTTCGCCATCAGGGGATTTGCATTTTGGTTCACTGATTGCCGCACTCGGGAGTTATC
TGCAAGCCCGTGCTCAAGGCGGGAAGTGGTTAGTTCGTATTGAAGATATTGATCCTCCCCGTGAAGTTCC
TGGCGCGGCCTCACGTATTTTAGCGGCCTTAGAGCATTATGGTCTCCATTGGGATGGCCCGGTTATCTAT
CAATCACAGCGCCATGAAGCGTATCGGGCCACGCTCAACTGGCTGGAACAGCAGGGATTAAGCTATTACT
GCACCTGCACCCGTAGCCGCATCCACCAGCTCGGCGGGTTCTACGACGGCTACTGCCGTGATCGTCATTT
ACCCGCTAGCGGCGCGGCTATCCGTTTGCGGCAGACTCAGCCGGTTTACGCTTTTTATGATAAATTACTC
GGCGAACTGCATGCTCACCCTGCGTTGGCACAAGAAGATTTTATTATCCGTCGCCGTGACGGTCTGTTCG
CTTATAATCTGGCGGTGGTGGTGGATGATGCTTTTCAGGGCGTGACCGAAATTGTACGAGGTGCTGATTT
GATTGAGCCGACAGTGCGCCAGATAGCGCTCTATCAGCAGTTGCAACACCCTGTCCCCGGCTATATACAC
TTGCCGTTGGCGCTGAATAATCAGGGGAATAAGCTCTCCAAGCAGAATCATGCTCCTCCCTTGCCTAATG
GCGATCCACGTCCTATTTTAATCGACGCATTAAAGTTTTTACGCCAACCGCTACCGGAATACTGGCAAGA
TCTTGATTTGTATTTATTATTACGTTATGCCGTTAAGCATTGGACGTTGGTGTCAATCCCACTCCAGGGG
GCAATAACCCCACAGAAAACACAACGGCATTCTCAAAGTAAGTATGGTGAGCTATG
Protein Sequence 
>gi|218930415|ref|YP_002348290.1| glutamyl-Q tRNA(Asp) synthetase [Yersinia pestis CO92] MVQQAVIQRSANQRATNQPTEYIGRFAPSPSGDLHFGSLIAALGSYLQARAQGGKWLVRIEDIDPPREVPGAASRILAALEHYGLHWDGPVIYQSQRHEAYRATLNWLEQQGLSYYCTCTRSRIHQLGGFYDGYCRDRHLPASGAAIRLRQTQPVYAFYDKLLGELHAHPALAQEDFIIRRRDGLFAYNLAVVVDDAFQGVTEIVRGADLIEPTVRQIALYQQLQHPVPGYIHLPLALNNQGNKLSKQNHAPPLPNGDPRPILIDALKFLRQPLPEYWQDLDLYLLLRYAVKHWTLVSIPLQGAITPQKTQRHSQSKYGEL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yadBC double mutant is less invasive of HeLa cells compared to the wild type and decreased virulence in bubonic plague in mice (Forman et al., 2008).
References
Forman et al., 2008: Forman S, Wulff CR, Myers-Morales T, Cowan C, Perry RD, Straley SC. yadBC of Yersinia pestis, a new virulence determinant for bubonic plague. Infection and immunity. 2008; 76(2); 578-587. [PubMed: 18025093].