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relA from Yersinia pestis CO92

Victor ID 1171
Gene Name relA from Yersinia pestis CO92
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1176197
NCBI Protein GI 16123529
Locus Tag YPO3380
Protein Accession NP_406842.1
Other Database IDs UniProtKB-ID: Q7CKD2_YERPE
UniRef100: UniRef100_A4TPX8
UniRef90: UniRef90_A4TPX8
UniRef50: UniRef50_P55133
UniParc: UPI00000DC624
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM84398.1
EMBL-CDS: AAS60581.1
EMBL-CDS: CAL21969.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO3380
KEGG: ypk:y0811
KEGG: ypm:YP_0306
HOGENOM: HBG594146
OMA: DLGHRCR
ProtClustDB: PRK10872
BioCyc
Taxonomy ID 214092
Gene Starting Position 3768707
Gene Ending Position 3770941
Gene Strand (Orientation) -
Protein Name GDP/GTP pyrophosphokinase
DNA Sequence 
>gi|16120353:3768707-3770941 Yersinia pestis CO92 chromosome, complete genome
CCTAATTGCCATGGAGGCGACGGGCGTCTATGACATCCGGCAACTGATTCAGTTTGGCCAATACCCGGCC
CAGCACCTGCAAGTTATAGATCTCGATATCCATATCGATAGTCGCCACCATCTTTTTGGTATCGCTGCGG
CTGGCAACGCCCAGTACGTTAACTTTCTCATTTGCCAGGATCGTAGTGATATCGCGCAATAACCCACTGC
GGTCATTAGCCGTAACCCGCACCACCAGCGAATAACCGCTGGAGTAGCTTTCGCCCCAGACTGCATCGAC
AATCCGTTCCGGTGCATGGGATTCCAATTCAGCCAACTGCTCACAATCTGCACGGTGAATCGATATCCCC
CGCCCTTGCGTGATAAAACCGATAATTTGATCACCGGGGATCGGCTGGCAACAACGGGCAATATGGTGCA
TCAGGTTACCGACACCTTCGACCACAATACGCCCACTGTCTTTGCTGGCGTTACGTGGCGCGGGCTGATG
CTTGTTATTCAGATGACGGAGTGCTTCTAGATCAGCCTCTTCTGCCGTTGGCTTATTCAGTTTGCCCTGG
AGGAAGTTCACCATCTGATTCAGACGGATATCACCCCCCCCAATCGCCGCTAACACTTCATCCATCGAAT
TCATGTTGTAACGCGGAACAAGCAGCTTCTCAGCCTCTTTCAGACTGATATCCAGATGCTCCAGCTCATC
ATCCAGCATTTGCCGGCCAGCCAGAATATTCTTATCTCTATCTTGTTTGCGGAACCAGTTATGAATTTTG
GAACGTCCGCGACTGGTCGTGATGTAACCGAGGTTAGGATTCAGCCAGTCACGGCTTGGGTTTGGCTGTT
TTTGAGTGATAATTTCAATTTGATCACCCATCTGCAACTGATAAGTAAACGGCACAATGCGGCCACTGAT
TTTGGCACCGATACAACGGTGGCCCACATCGCTATGAATATGGTAGGCAAAATCCAGCGGCGTCGAGCCG
GCAGGCAGGTCAATCACATCGCCTTTCGGTGTAAACACGTACACCCGATCATCAAATACCTGGCTGCGCA
CTTCATCCAGCATTTCGCCAGAATCAGCCATCTCTTCCTGCCAAGCGATCAATTTACGTAACCAGGCGAT
TCGCCCTTCATAACTCGAACGGCCCGCTGCCACGGCCCCTTCTTTATATTTCCAGTGCGCAGCAACCCCC
AACTCGGCATCTTCATGCATCTGGCGGGTGCGGATCTGAATCTCTAACGTTTTACCTCGTGGCCCAAGCA
CCACGGTATGGATCGATTGGTAACCATTTGGCTTAGGGTTGGCCACATAATCATCAAATTCATCAGGTAA
ATGCCGGAAGTGCGTGTGAACAATCCCTAACGCGGCATAACAATCCTGCAAACGTTCCACCACCACCCGC
ACCGCGCGGACGTCGAATAGCTCATCGAAGGCCAGCGACTTTTTCTGCATTTTGCGCCAAATGCTGTAGA
TATGCTTCGGTCGGCCATAAATGTCGGCTTTAATGCCTTCGTCGGCCATCGCCTTATGTAATGAAGCAAC
GAAGTCATCAATAAATTGTTCGCGATCAATACGCCTCTCGTGGAGTAATTTGGCGATTTTCTTATATTCA
TCTGGATGCAGATAACGGAAGCAGAAATCCTCCAGCTCCCATTTAATCTGGCCAATCCCCAAACGGTTCG
CCAGTGGTGCGTAAATATTGGAACACTCTTTAGCCGCCAGAACACGTTCATCTTCCGGTGCATCTTTGAC
TTCACGCAGATGAGCGATCCGCTCTGCCAGCTTGATCACCACGCAGCGGAAATCCTCCACCATCGCCAAT
AACATACGGCGCACGTTATCCACTTGCTCCGAGCTCATGGAATCGTTGTGAGTGGCTTTTAACTGGCGGA
TAGCATCCATATCACGCACGCCGTGTACCAGATACGTAATCCCCTTACCGAATTGCTCGGTCAGGGTAGT
TTCGTCCACGATATTGGCATCTACCAGCGGGAACAGCAGCGCCGCGCGCATACTGTCGTTATCCATACTC
AGAGTGGAAAGAATTTCAACCATTTCAAGACCGCGCCACAGTAATAACGAGGCATCGGGATGGTTTTGCG
TCTGTTGTTCACAGTAACGCCAGGTTTCGGCTAATCGCTCAGATGACTGCGGATTGGCAAGCCCTAAACT
GGCAATCCAATCGTCAAGAGCAAACTCACCCGCTGGGTTTAAATGCGCACTTCGTACCGCAACCA
Protein Sequence 
>gi|218930397|ref|YP_002348272.1| GDP/GTP pyrophosphokinase [Yersinia pestis CO92] MVAVRSAHLNPAGEFALDDWIASLGLANPQSSERLAETWRYCEQQTQNHPDASLLLWRGLEMVEILSTLSMDNDSMRAALLFPLVDANIVDETTLTEQFGKGITYLVHGVRDMDAIRQLKATHNDSMSSEQVDNVRRMLLAMVEDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECSNIYAPLANRLGIGQIKWELEDFCFRYLHPDEYKKIAKLLHERRIDREQFIDDFVASLHKAMADEGIKADIYGRPKHIYSIWRKMQKKSLAFDELFDVRAVRVVVERLQDCYAALGIVHTHFRHLPDEFDDYVANPKPNGYQSIHTVVLGPRGKTLEIQIRTRQMHEDAELGVAAHWKYKEGAVAAGRSSYEGRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVIDLPAGSTPLDFAYHIHSDVGHRCIGAKISGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYITTSRGRSKIHNWFRKQDRDKNILAGRQMLDDELEHLDISLKEAEKLLVPRYNMNSMDEVLAAIGGGDIRLNQMVNFLQGKLNKPTAEEADLEALRHLNNKHQPAPRNASKDSGRIVVEGVGNLMHHIARCCQPIPGDQIIGFITQGRGISIHRADCEQLAELESHAPERIVDAVWGESYSSGYSLVVRVTANDRSGLLRDITTILANEKVNVLGVASRSDTKKMVATIDMDIEIYNLQVLGRVLAKLNQLPDVIDARRLHGN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: relA spoT deletion mutants are attenuated in mice (Sun et al., 2009).
References
Sun et al., 2009: Sun W, Roland KL, Branger CG, Kuang X, Curtiss R 3rd. The role of relA and spoT in Yersinia pestis KIM5 pathogenicity. PloS one. 2009; 4(8); e6720. [PubMed: 19701461].