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purK from Yersinia pestis CO92

Victor ID 1168
Gene Name purK from Yersinia pestis CO92
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1175898
NCBI Protein GI 16123254
Locus Tag YPO3077
Protein Accession NP_406567.1
Other Database IDs UniProtKB-ID: Q7CJZ2_YERPE
UniRef100: UniRef100_A4TP67
UniRef90: UniRef90_A4TP67
UniRef50: UniRef50_P43850
UniParc: UPI00000DC82F
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM84680.1
EMBL-CDS: AAS61106.1
EMBL-CDS: CAL21679.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
HSSP: P09029
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO3077
KEGG: ypk:y1102
KEGG: ypm:YP_0847
HOGENOM: HBG516369
OMA: LADRSEW
ProtClustDB: PR
Taxonomy ID 214092
Gene Starting Position 3432258
Gene Ending Position 3433322
Gene Strand (Orientation) +
Protein Name phosphoribosylaminoimidazole carboxylase ATPase subunit
DNA Sequence 
>gi|16120353:3432258-3433322 Yersinia pestis CO92 chromosome, complete genome
CATGAAACCAGTTTGTGTACTGGGTAATGGCCAGTTAGGGCGAATGCTGCGGCAGGCAGGTGAACCGCTG
GGAATTGCGGTTTATCCCGTCGGCTTAGATGCTGAACCTGAAGCGGTGCCTTATCAGCACAGTGTGATCA
CCGCTGAAATTGAACGTTGGCCGGAAACCGCCTTAACCCGTGAATTAGCTACCCATACTGCTTTTGTTAA
TCGCGATATTTTTCCACGTCTGGCAGATCGTCTGCCCCAAAAGCAGTTACTCGATAGCTTGGGTTTGGCA
ACTGCGCCGTGGCAATTGTTATCCAGCGCCAGTGAATGGCCTGAGGTGTTCGCCACGTTGGGTGAGCTAG
CCATCGTAAAACGGCGGGTCGGCGGCTATGACGGCCGGGGTCAATGGCGTTTACGCCCTGGTGAGCAGGG
TACCTTACCCCCCGATGCTTACGGCGAGTGTATTGTCGAACAGGGGATTAACTTCTCCGGCGAAGTCTCA
TTGATCGGCGCGCGCAGCCACCAAGGTGAATCGGTATTTTATCCACTGACCCATAATCTGCATGAAGATG
GCATTTTGCGCATGAGCGTGGCATTACCACAGCCCAACAGCAAACTACAGCAGCAAGCCGAAAAAATGCT
GTCAGCCATTATGGATAAGCTGAATTATGTCGGTGTGATGGCGATGGAGTGTTTTATCGTCGGCGACCGT
CTGTTGATCAATGAACTGGCCCCGCGCGTTCATAACAGTGGTCACTGGACACAAAACGGCGCATCAATTA
GCCAGTTCGAATTGCATCTGCGGGCCATTTTGGATCTGCCACTGCCGCAGCCGGTGGTGAATACCCCGTC
AGCGATGGTTAATCTGATTGGCACGCCAGTAAATATTCAGTGGCTGTCTCTGCCATTAGTACATCTGCAT
TGGTACGACAAAGAAGTCCGTGAAGGCCGCAAAGTTGGTCATCTGAATTTAAACGATCCAGAGGGTACGG
CATTAAGCGCATCCCTGGCCGCACTGGCTCCTTTGCTACCCGCGGAGTATCAGAACGCACTGCGTTGGGC
GCAAGATAAGTTATA
Protein Sequence 
>gi|218930122|ref|YP_002347997.1| phosphoribosylaminoimidazole carboxylase ATPase subunit [Yersinia pestis CO92] MKPVCVLGNGQLGRMLRQAGEPLGIAVYPVGLDAEPEAVPYQHSVITAEIERWPETALTRELATHTAFVNRDIFPRLADRLPQKQLLDSLGLATAPWQLLSSASEWPEVFATLGELAIVKRRVGGYDGRGQWRLRPGEQGTLPPDAYGECIVEQGINFSGEVSLIGARSHQGESVFYPLTHNLHEDGILRMSVALPQPNSKLQQQAEKMLSAIMDKLNYVGVMAMECFIVGDRLLINELAPRVHNSGHWTQNGASISQFELHLRAILDLPLPQPVVNTPSAMVNLIGTPVNIQWLSLPLVHLHWYDKEVREGRKVGHLNLNDPEGTALSASLAALAPLLPAEYQNALRWAQDKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purK mutant is attenuated in mice (Flashner et al., 2004).
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].