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ahpC from Mycobacterium tuberculosis H37Rv

Victor ID 116
Gene Name ahpC from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885717
NCBI Protein GI 15609565
Locus Tag Rv2428
Protein Accession NP_216944.1
Other Database IDs UniProtKB-ID: AHPC_MYCTU
UniRef100: UniRef100_Q7BHK8
UniRef90: UniRef90_Q7BHK8
UniRef50: UniRef50_Q7BHK8
UniParc: UPI000002FC7F
EMBL: U18264
EMBL: U16243
EMBL: AF313459
EMBL: AF313460
EMBL: AF313461
EMBL: AF313462
EMBL: AF313463
EMBL: BX842579
EMBL: AE000516
EMBL-CDS: AAA79919.1
EMBL-CDS: AAC43585.1
EMBL-CDS: AAG34172.1
EMBL-CDS: AAG34173.1
EMBL-CDS: AAG34174.1
EMBL-CDS: AAG34175.1
EMBL-CDS: AAG34176.1
EMBL-CDS: CAB03768.1
EMBL-CDS: AAK46800.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 2
Taxonomy ID 83332
Gene Starting Position 2726192
Gene Ending Position 2726779
Gene Strand (Orientation) +
Protein Name ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL HYDROPEROXIDASE C)
DNA Sequence 
>gi|57116681:2726192-2726779 Mycobacterium tuberculosis H37Rv, complete genome
CATGCCACTGCTAACCATTGGCGATCAATTCCCCGCCTACCAGCTCACCGCTCTCATCGGCGGTGACCTG
TCCAAGGTCGACGCCAAGCAGCCCGGCGACTACTTCACCACTATCACCAGTGACGAACACCCAGGCAAGT
GGCGGGTGGTGTTCTTTTGGCCGAAAGACTTCACGTTCGTGTGCCCTACCGAGATCGCGGCGTTCAGCAA
GCTCAATGACGAGTTCGAGGACCGCGACGCCCAGATCCTGGGGGTTTCGATTGACAGCGAATTCGCGCAT
TTCCAGTGGCGTGCACAGCACAACGACCTCAAAACGTTACCCTTCCCGATGCTCTCCGACATCAAGCGCG
AACTCAGCCAAGCCGCAGGTGTCCTCAACGCCGACGGTGTGGCCGACCGCGTGACCTTTATCGTCGACCC
CAACAACGAGATCCAGTTCGTCTCGGCCACCGCCGGTTCGGTGGGACGCAACGTCGATGAGGTACTGCGA
GTGCTCGACGCCCTCCAGTCCGACGAGCTGTGCGCATGCAACTGGCGCAAGGGCGACCCGACGCTAGACG
CTGGCGAACTCCTCAAGGCTTCGGCCTA
Protein Sequence 
>gi|15609565|ref|NP_216944.1| alkyl hydroperoxide reductase subunit C [Mycobacterium tuberculosis H37Rv] MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVVFFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQHNDLKTLPFPMLSDIKRELSQAAGVLNADGVADRVTFIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQSDELCACNWRKGDPTLDAGELLKASA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ahpC mutant has decreased survival in unstimulated macrophages compared to the wild type (Master et al., 2002).
COG COG0450O, under O: Posttranslational modification, protein turnover, chaperones
References
Master et al., 2002: Master SS, Springer B, Sander P, Boettger EC, Deretic V, Timmins GS. Oxidative stress response genes in Mycobacterium tuberculosis: role of ahpC in resistance to peroxynitrite and stage-specific survival in macrophages. Microbiology (Reading, England). 2002; 148(Pt 10); 3139-3144. [PubMed: 12368447].