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YPO1994

Victor ID 1151
Gene Name YPO1994
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1174831
NCBI Protein GI 218929104
Locus Tag YPO1994
Genbank Accession AL590842
Protein Accession YP_002346979
Other Database IDs UniProtKB-ID: Q7CI89_YERPE
UniRef100: UniRef100_A4TJR5
UniRef90: UniRef90_A4TJR5
UniRef50: UniRef50_A4TJR5
UniParc: UPI00000DC8AE
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM85875.1
EMBL-CDS: AAS62061.1
EMBL-CDS: CAL20630.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO1994
KEGG: ypk:y2316
KEGG: ypm:YP_1841
HOGENOM: HBG273664
OMA: SINIMEH
ProtClustDB: CLSK889065
BioC
Taxonomy ID 214092
Gene Starting Position 2266291
Gene Ending Position 2267241
Gene Strand (Orientation) -
Protein Name hypothetical protein
Protein pI 6.61
Protein Weight 34678.58
Protein Length 316
Protein Note Weakly similar to the internal region of Saccharomyces cerevisiae nonsense-mediated mRNA decay protein 2 Nmd2 or Upf2 or ifs1 or Sua1 or Yhr077C SW:NMD2_YEAST (P38798) (1089 aa) fasta scores: E(): 0.15,26.0% id in 289 aa. It also shows similarity to the N-terminus of Mus musculus calreticulin precursor CalR SW:CRTC_MOUSE (P14211) (416 aa) fasta scores: E(): 0.3,23.7% id in 215 aa
DNA Sequence 
>gi|16120353:2266291-2267241 Yersinia pestis CO92 chromosome, complete genome
ATTAGCGGGGTTTTGGACTCATGCATGGCATGCTTCCAATACTGTGAGAAATCTTATTTTTGATATAGAG
GCTTTGGTCTTTAAATGCTTGTTCACTAATGCTCTTTATATCACTCACATTACCTTTTTTTTGGGCGTGC
TTAAGTAAAGCTTCATAAGCGATTAATCGTATCTCTTCTCGATGGTTACAAAGAGACACTTTGTGAACCA
GTTGACGACTTTTTTCATTTTCAAGACTCAGCAGGCCGTTATATAACACATTTTGAAAAGCGTAGCGCTC
ATATCTTCCCTTTTTAATTCTTGCCTCTATTTTTCCTTCCAATGCATCTGAATCTATCTGAAATTCGTAT
TGATGCTTCGATTTTATTGGTCGCACTATTAAATTGAGCGATACTGATAATTCATCAGGCGGATATTGAG
TATGAACATCCTTACTACGAAAATAAAACATAACTGTATTCGGGGAAAGAATCTTATCTCCATAACAATT
AAGTTCTACAACTTCGTTATTTACGCCACTAACTTTATCGTAATCATAGTCATAGAGCCGAGTTCGATAG
CCACCTCCAAAAAAATTCACTGTCCAAAAGTCAAAATTATGATCATGTGCTTCTTCGTAGGAATAAGGTG
TCCGATCTAATTTTCCCTGCAATGGGAGCCACATAACAAGACGAATAGTTATGCGTTCATTACTGTAAAG
AATAAAACTCGGTGCCTGTATGTCATTCTCCAGCTGGAATTGATAAGGGTTCTCCAACTCGGTAATGATC
TGCGAAAAAATTTCATCTTTATTAGCCGCGTAGGCTGAAAGCCATGAACCTACTTCAAGGATTTCGCTTT
CCACATAAATCCCATTTGCCACATTGGAAATTGCCGATGAGTGACTCAAAATTCCTAATAAATCTTGTAG
TGTCAGTGATTTATTCACTGGCGTAATATTATTTAGGAGCA
Protein Sequence 
>gi|218929104|ref|YP_002346979.1| hypothetical protein YPO1994 [Yersinia pestis CO92]
MLLNNITPVNKSLTLQDLLGILSHSSAISNVANGIYVESEILEVGSWLSAYAANKDEIFSQIITELENPY
QFQLENDIQAPSFILYSNERITIRLVMWLPLQGKLDRTPYSYEEAHDHNFDFWTVNFFGGGYRTRLYDYD
YDKVSGVNNEVVELNCYGDKILSPNTVMFYFRSKDVHTQYPPDELSVSLNLIVRPIKSKHQYEFQIDSDA
LEGKIEARIKKGRYERYAFQNVLYNGLLSLENEKSRQLVHKVSLCNHREEIRLIAYEALLKHAQKKGNVS
DIKSISEQAFKDQSLYIKNKISHSIGSMPCMSPKPR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: YPO1994 mutant is attenuated in mice (Flashner et al., 2004).
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].