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ail

Victor ID 1147
Gene Name ail
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1174696
NCBI Protein GI 218928979
Locus Tag YPO1860
Genbank Accession AL590842
Protein Accession YP_002346854
Other Database IDs UniProtKB-ID: Q7CI12_YERPE
UniRef100: UniRef100_A4TK46
UniRef90: UniRef90_A4TK46
UniRef50: UniRef50_A4TK46
UniParc: UPI00000DC855
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM86003.1
EMBL-CDS: AAS61768.1
EMBL-CDS: CAL20500.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
HSSP: P36546
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO1860
KEGG: ypk:y2446
KEGG: ypm:YP_1533
HOGENOM: HBG685626
OMA: HASTNAP
ProtClustDB: CL
Taxonomy ID 214092
Gene Starting Position 2109268
Gene Ending Position 2109819
Gene Strand (Orientation) +
Protein Name attachment invasion locus protein
Protein pI 6.26
Protein Weight 19315.31
Protein Length 183
Protein Note Similar to Yersinia enterocolitica attachment invasion locus protein precursor Ail SW:AIL_YEREN (P16454) (178 aa) fasta scores: E(): 3.3e-28, 47.8% id in 184 aa,and to Yersinia pseudotuberculosis attachment invasion locus protein precursor Ail SW:AIL_YERPS (Q56957) (182 aa) fasta scores: E(): 5.8e-26, 44.8% id in 183 aa. Similar to YPO2905, YPO2190 and YPO2506
DNA Sequence 
>gi|16120353:2109268-2109819 Yersinia pestis CO92 chromosome, complete genome
AATGAAAAATAAAACCACATTGGCTGCATTTATAACAGCGATCTTATTAAGCAGTTCAGCGGCCTATGCG
GCAGGGGATCGTACCATCTCATTGGGGTATGCTCAGGGAGATGTAAGACTCGGTGATGGAAATCGAAAAG
ACATTAGATTGGACGATGATCTTAAAGGGATTAATGTTAAATATCTCCATAAGTTGAGTGAAATGTTCGG
TGCAATAGGCTCTTTTACTTACACGGATTTAAATTATGATTATCTAAATAATAATGTCAAAATTGGGGAT
GCATCCTTTGATTATTATTCGCTGATGGTTGGGCCCAGCGTACATTTTAATGAGTTTTTCAGCATGTATG
CATTATTGGGAATTGGGCATGGGAACGCGAAAGCATCTGTATTAGGTTACGGTAAAAAAGAGGAGCAAGA
CTCTTTGGCATATGGTGTTGGGATGCAATTTAATCCACTTAACAATATTGCTATTGATGCTTCATACGAG
TATACAAAACTTAAAGATGCTAATATCGGTACATGGGTTTTAGGCATTGGCTATCGTTTTTA
Protein Sequence 
>gi|218928979|ref|YP_002346854.1| attachment invasion locus protein [Yersinia pestis CO92]
MKNKTTLAAFITAILLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFG
AIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGNAKASVLGYGKKEEQD
SLAYGVGMQFNPLNNIAIDASYEYTKLKDANIGTWVLGIGYRF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a Y. pestis ail deletion mutant was rapidly killed by sera from all mammals tested except mice (Bartra et al., 2008).
References
Bartra et al., 2008: Bartra SS, Styer KL, O'Bryant DM, Nilles ML, Hinnebusch BJ, Aballay A, Plano GV. Resistance of Yersinia pestis to complement-dependent killing is mediated by the Ail outer membrane protein. Infection and immunity. 2008; 76(2); 612-622. [PubMed: 18025094].