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YPO1388

Victor ID 1144
Gene Name YPO1388
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1174229
NCBI Protein GI 218928536
Locus Tag YPO1388
Genbank Accession AL590842
Protein Accession YP_002346411
Other Database IDs UniProtKB-ID: Q7CHJ5_YERPE
UniRef100: UniRef100_C4GVT1
UniRef90: UniRef90_C4GVT1
UniRef50: UniRef50_C4GVT1
UniParc: UPI00000DC842
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM86337.1
EMBL-CDS: AAS61448.1
EMBL-CDS: CAL20040.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
TCDB: 1.B.40.1.4
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO1388
KEGG: ypk:y2785
KEGG: ypm:YP_1205
HOGENOM: HBG757739
OMA: PIAIANN
ProtClustDB
Taxonomy ID 214092
Gene Starting Position 1566261
Gene Ending Position 1568129
Gene Strand (Orientation) +
Protein Name hypothetical protein
Protein pI 3.94
Protein Weight 61904.35
Protein Length 622
Protein Note C-terminal region of the CDS is similar to Yersinia enterocolitica invasin precursor YadA SW:YADA_YEREN (P31489) (455 aa) fasta scores: E(): 3.5e-10, 26.8% id in 355 aa. Internal region of the CDS is similar to the N-terminus Yersinia pestis putative autotransporter protein YapD TR:CAC14223 (EMBL: AJ277627) (1457 aa) fasta scores: E(): 8.8e-06, 23.6% id in 559 aa
DNA Sequence 
>gi|16120353:1566261-1568129 Yersinia pestis CO92 chromosome, complete genome
AATGAATAAGGAAATTAAACGGATGCAACGGATGCAATGCATATATATCGCCACTTGGTTAATCGCAGTA
TTTACTTCGCCGATAGTGATAGCTAACAATACGAATATTAATGGCAGTACCAATAATAACGGTAATGGTA
CAATCAATATTTTTGACGCCAGCAGTAATAACGATATTCATACACTAACCGGTCTTGGTAATGAGCAGTT
GGGAGGATTTAGTAATCATCTTATCGACTCTCATAATAATACGATAGACGGTGGTCAGAGTAACAACCTG
GTAAGTAGCGATGGCAATATGATCAGCGCCATTAGCTTGGGCGATGGCCTCTTCTACGGCGCGCAGAATA
ACACGTTAATAAACTCAAACAACAACCTACTTATTGTCACTCAGGGCAGTACTATAATAGATTCTGATAG
TAATACTGTGTCTGGCATTAGTAATAATCTTATAGAGAGCAACAGCAATATTATCGGTAATGAAAATAGT
TGTTATTCGGATCCCGCGTCCCCATCAGGAGCGTGGTGCGTTGACAATCAAAATACGCTCATTGGCAGTG
ATAACAATACGATCACTGGTGCGCTGAATGGTCTTCACAACAGTCATAACAATGATATTATTGCTAGCTC
TGTAAATAATTTAATGGATACGCATAATAATATTATCGCGGGAGGGCACTACAACACCATTAGTGGTGGT
GGAAACAATGACATTTTTGGGAGTGAAAACAATGTTACTGACAGCACCGACGCCAATATCAATGGTAGTA
ATAACTACGTGATAGATGGGAATGGAATTGGTCGAGATGATTTGACTGAAGATAACTCTATATTGGGCGG
CTCTGGCAATATGGGCGTGGGGGATTCAGTAACCGCGATTACCAATAGCGTGGTGTTCGGCGGTAATACA
TCTGGTAATTCAACCGGCTCCACTCTGACAGATTCTGTATCGGTTAGCGGCAACGGTACATCGGGGAATA
ATGTCGTTAATATCGGCGGAGCGGCAAACGGTAATAATAGTGCTAGCTTAGGTACAGGCTCGGTATCCTC
TGAAGGAGGAATTGCATTGGGTAGCGGTTCGATTGCTACACGGAATGATGAACTGAATATCGGTGATAGA
CAAATTACCAGCGTTAAAAAAGGTGTTGAGAATACAGATACAATCAATGTTAGTCAGTTAAACGATAGCT
TTGATGATGTTCTGAATTTATCAAATGAATATTCTGACAACTCTTTTTCCACTGTCACTGAAAATATAAA
TAATTATACTGATGCCTCATTAGATACTGTGTTGAATACAACTGGTGAATATACCGACAACTCAATATTA
TTGGTTACTAATGAAAGCAATAATTATACTGACAATGGCATGGAGAGTGTTAGTAATTATGCAAATATCT
ATGCTGATGAATCTTTGTTAGCTATCTATAATGAAGAGGCTAATTACATGTCTAATCTTATAGATGTGAC
GTTAAATAATGCTAATAACTATACTGATCTTTCAGTTAATACCATTATATATACCGGAAAACAATATACA
GACTCTCGAATCAATGAGTACCAACGTACTTTTAAAAATGAATTTTTAACCTATTCTAATGGAAAATTTG
GCGGTTTTGATAAAGATATTAATCAAAAGCAGAAACAATTAAACGCGGGAATAGCGGCGACGATGGCTGC
TGCGGTTATTCCTCAAAAATCGGGTTCTAAAGTCTCTATTGGTGTCGGGCTTGCAGGATATAGCGATCAA
GGCGCAGGATCTGTGGGAGCGATTTGGCATGTAAATCAACGAATCACAATGAATACAACGATGACTTACG
ATACTCAACGTGGTGTTAGTTTATTAACGGGTTTATCTATCGGCATATG
Protein Sequence 
>gi|218928536|ref|YP_002346411.1| hypothetical protein YPO1388 [Yersinia pestis CO92]
MNKEIKRMQRMQCIYIATWLIAVFTSPIVIANNTNINGSTNNNGNGTINIFDASSNNDIHTLTGLGNEQL
GGFSNHLIDSHNNTIDGGQSNNLVSSDGNMISAISLGDGLFYGAQNNTLINSNNNLLIVTQGSTIIDSDS
NTVSGISNNLIESNSNIIGNENSCYSDPASPSGAWCVDNQNTLIGSDNNTITGALNGLHNSHNNDIIASS
VNNLMDTHNNIIAGGHYNTISGGGNNDIFGSENNVTDSTDANINGSNNYVIDGNGIGRDDLTEDNSILGG
SGNMGVGDSVTAITNSVVFGGNTSGNSTGSTLTDSVSVSGNGTSGNNVVNIGGAANGNNSASLGTGSVSS
EGGIALGSGSIATRNDELNIGDRQITSVKKGVENTDTINVSQLNDSFDDVLNLSNEYSDNSFSTVTENIN
NYTDASLDTVLNTTGEYTDNSILLVTNESNNYTDNGMESVSNYANIYADESLLAIYNEEANYMSNLIDVT
LNNANNYTDLSVNTIIYTGKQYTDSRINEYQRTFKNEFLTYSNGKFGGFDKDINQKQKQLNAGIAATMAA
AVIPQKSGSKVSIGVGLAGYSDQGAGSVGAIWHVNQRITMNTTMTYDTQRGVSLLTGLSIGI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yadBC (yadC is YPO1388) mutant is attenuated in mice and is less invasive of HeLa cells than the wild-type (Forman et al., 2008).
References
Forman et al., 2008: Forman S, Wulff CR, Myers-Morales T, Cowan C, Perry RD, Straley SC. yadBC of Yersinia pestis, a new virulence determinant for bubonic plague. Infection and immunity. 2008; 76(2); 578-587. [PubMed: 18025093].