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arcA

Victor ID 1135
Gene Name arcA
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1173302
NCBI Protein GI 218927655
Locus Tag YPO0458
Genbank Accession AL590842
Protein Accession YP_002345530
Other Database IDs UniProtKB-ID: Q7CG70_YERPE
UniRef100: UniRef100_A4TQH2
UniRef90: UniRef90_P0A9Q3
UniRef50: UniRef50_P0A9Q3
UniParc: UPI00000DCC6B
EMBL: AE009952
EMBL: AE017042
EMBL: AL590842
EMBL-CDS: AAM87269.1
EMBL-CDS: AAS63873.1
EMBL-CDS: CAL19137.1
RefSeq_NT: NC_004088.1
RefSeq_NT: NC_005810.1
RefSeq_NT: NC_003143.1
HSSP: P08402
GenomeReviews: AE009952_GR
GenomeReviews: AE017042_GR
GenomeReviews: AL590842_GR
KEGG: ype:YPO0458
KEGG: ypk:y3721
KEGG: ypm:YP_3725
HOGENOM: HBG753323
OMA: ESYRFNG
ProtClustDB: PR
Taxonomy ID 214092
Gene Starting Position 481574
Gene Ending Position 482290
Gene Strand (Orientation) -
Protein Name two-component response regulator
Protein pI 5.64
Protein Weight 26069.71
Protein Length 238
Protein Note Also known as cpxC; dye; fexA; msp; seg; sfrASimilar to Escherichia coli aerobic respiration control protein ArcA SW:ARCA_ECOLI (P03026) (238 aa) fasta scores: E(): 0, 92.9% id in 238 aa, and to Vibrio cholerae aerobic respiration control protein FexA TR:Q9KPJ9 (EMBL: AE004307) (238 aa) fasta scores: E(): 0, 85.3% id in 238 aa
DNA Sequence 
>gi|16120353:481574-482290 Yersinia pestis CO92 chromosome, complete genome
ATTACTCTTCTAGATCGCCACAGAAACGATAGCCTTCACCGTGGATGGTGGCGATAATTTCTGGTGTATC
CGGCGTAGATTCGAAGTGTTTACGAATACGGCGGATAGTCACATCGACAGTACGGTCATGAGGTTTCAAC
TCGCGACCGGTCATTTTTTTCAACAATTCACCGCGGGATTGAATTTTCCCTGGGTTTTCGCAGAAATGCA
GCATGGCGCGGAACTCACTGCGTGGCAGTTTGTAATGCTCACCCGTAGGGCTGACCAGTGAGCGGCTATT
GATATCCAGCTCCCAACCATTAAATTTGTAGCTTTCAACCAAACGGCGTTCTTCGCCTACACTGCTCAGA
TTCATGGTGCGAGACAGCAGGTTACGGGCACGGATGGTTAATTCACGTGGGTTGAAAGGTTTCGTGATGT
AATCATCAGCACCAATTTCCAAACCAAGGATCTTATCAACTTCGTTATCACGACCGGTGAGGAACATGAG
AGCAACACTGGCTTGCTCACGGAGCTCCCGTGCTAGCAACAAGCCATTTTTGCCTGGCAGATTGATGTCC
ATGATCACTAAGTTGATGTCATTTTCAGACAGGATATGGTGCATTTCTGCCCCATCATTGGCTTCATAAA
CAACGTAGCCTTCCGCCTCGAAAATGCTCTTTAGTGTGTTGCGAGTGACTATCTCGTCTTCTACGATCAG
AATGTGGGGGGTCTGCA
Protein Sequence 
>gi|218927655|ref|YP_002345530.1| two-component response regulator [Yersinia pestis CO92]
MQTPHILIVEDEIVTRNTLKSIFEAEGYVVYEANDGAEMHHILSENDINLVIMDINLPGKNGLLLARELR
EQASVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLSRTMNLSSVGEERRLVESYKFN
GWELDINSRSLVSPTGEHYKLPRSEFRAMLHFCENPGKIQSRGELLKKMTGRELKPHDRTVDVTIRRIRK
HFESTPDTPEIIATIHGEGYRFCGDLEE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: arcA mutant is attenuated in mice (Flashner et al., 2004).
References
Flashner et al., 2004: Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S. Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates. Infection and immunity. 2004; 72(2); 908-915. [PubMed: 14742535].