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ypkA from Yersinia pestis CO92

Victor ID 1128
Gene Name ypkA from Yersinia pestis CO92
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1172717
NCBI Protein GI 16082760
Locus Tag YPCD1.72c
Protein Accession NP_395206.1
Other Database IDs UniProtKB-ID: YPKA_YERPE
UniRef100: UniRef100_Q9RI12
UniRef90: UniRef90_Q9RI12
UniRef50: UniRef50_Q9RI12
UniParc: UPI00000D1292
EMBL: AF074612
EMBL: AF053946
EMBL: AL117189
EMBL: AE017043
EMBL-CDS: AAC69765.1
EMBL-CDS: AAC62602.1
EMBL-CDS: CAB54949.1
EMBL-CDS: AAS58532.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
RefSeq_NT: NC_005813.1
MINT: MINT-1503406
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.72c
KEGG: ypm:YP_pCD13
HOGENOM: HBG299066
OMA:
Taxonomy ID 214092
Plasmid No pCD1
Gene Starting Position 51472
Gene Ending Position 53670
Gene Strand (Orientation) -
Protein Name secreted protein kinase
DNA Sequence 
>gi|16082691:51472-53670 Yersinia pestis CO92 plasmid pCD1, complete sequence
GTCACATCCATTCCCGCTCCAACCGGTTCAGTCGCTCGGCGATGGTCGTCAGCTCTCGCAACTTTTCTCT
CTGTTCAACCAAATGCTCATCCATTAAACTGCTTCGTCCAAGTTGAATCAGTAGTGGAATAGAGTCCACT
GTAAAGTTTCGCATATCATCAGTAAACTCCGATACCTCCTGTAGCGTAATAGCTGCATGGGCCGCCATCA
TCTGACGGTGAATTGCGGTATACTGCTCAGTGCCGAATTTCACTACAGGCCGGGTACTGTCAAAACGCTG
CAGGGACTGACGAGCAACATCGGCCCAAGAACCTGAACGATTAATCAGAATAGATAATTGCGCTTTCGCA
CTCTCCTGCTGCTGCTGGAGAGTATTCAATTGCTGCGACAAGGTGATCTTAGCCTCAGTTAATCGATTCA
GGAAGCCGTAGGTTTCAGAGGACACGGGCTGCCCTTGCTGTGACAAGGTGACTAAGACCTCTAAAAGCGT
TTCCAGGTGCTTATGTGCGCGCACTAGTGAACCGATATCAGAAAAAGAGTGTGTCTGGTCCAGATGCTTC
TGGATCCTCTGCAGTGAAGGTTCGACGATCGATAGCATAAAGTTACTGCGATGATAGGGGGATACTTCCG
TACTGGAATTCTTGGTATCCCCTTCTCTGCCTTTGACATAGTCTTCAATCACTCTGTAAGTCTTCAGAAT
CAAACTGTTAAAACTCTTCAACTGATCCTTGTCTACTCCCCCCTCGCGTTCGGCCTTGTCGAGTGCCACC
AACATGGTATCAAGATCCGACAAAACCCCCCCCATATCCAATTGCTTAGTTGCTGCACTGCTCAAATGCG
TCCTAAGCAAATCAGATAGCTCCCGAAGCTTCTTGGGTGTTATCCGCCTTACATCAGTAGATAATGGGCT
CATTTCTCCGGTTAGGGTATCTTTTAGGATCTGCTTGGCCGACTCCTCGTCGATAGTTCCGTCGCTCAAG
AACTCGTGGAGTCTGGCTTCGTTGGAATCAGGTCTTGAGTCAGCGGAAACGCCAAGGATGTCTGTGATGA
AGCGTGTATAGGCTGTCTCGACTCCAGCTATACCAGGTCGATGGATTGGATAACCATTCTCATCCATTAC
GTGCGCTGGTTCTGAGGTAATGAATCTCAGTCCTTGATTAGGCTTTATCTCCGGATTTTTCTCAAAACCT
TCGATACAATGTAGAAGGGTTGACACTACGAGAAAAACATCGCTCTTTTCTGATGCGCCTAGGTTTCCTA
CTCCAAGCTCCGGCGCTTTGAAGGATTCTGTAAACCCCTTAGGTTGTTCCCCTGAACGAGAGTGTAATCC
TAGATCAATAACAACGGGCTCTCCGCTAGCGCGGTCAAATACCACATTACCGGGTTTGATATCGTTATGT
ACTACCCCTGCCTTGGCAAGGTGATTGGTTACATCTAATAGCCGATGGGCAATAAACTTGATCGTTCCCC
AGTAGGCTTCACTATTGATCTTTCCTTGCTTCCAGCTATCGGCGAGGGTTCTTAGTGTGTCAGAACAACG
CCAACCATCCACCTCATCCATCAGCAATGCTTCCTCCTTACGGTTACCGTATGGCACCACAGCCATGCCA
TGAACATTGGCAAGATTAGGATGTTTGCCCGCGGTTTTATAGATGTGTTTATAAGCCTCCAGTTCTGCGA
ACAAATGCCCCTCGGCAATGGAGCGTTCAATCTTAGCTACCAACCGCTGCTTATCCTTAGTTTCTATTAT
ACTAATATGGCTTTCGCCCTCGGCAAACTTATCGGTTTCAGCCACTCGCATCCCTTCAAGATCCGGAGCT
CCTGACAAGGGCTCCCCTTTCCAACCCAGCGGCAGTTCGGTCTGTGGCTTGGCTCCAAAGAGATTACTGA
GAGCATTGGGGATATCAGACCTTAGCTCCTGCGAAGTCGTTTTCTGGGCCGCATGGAGTGTGTCAGTAAG
GTTACGAGCAATTGAAAAGTTAAACATCTTCCCCGAAAAGATCTTACCAACCCCTTCTCGAAAGAGAGAA
AAACCACTGTGGGGGTTCAAGCGCAACACTTGATTATCGATAATTCTATACCGTTTTCCTCCGATATTGA
GCTCACCGACAGGATTTTGCCAATGTTGGCTGATGCGCTCATGAGCTTTGGCGAGGGAGATCGACGGTGG
CATAGTTCCCATGATTTTCACGCTTTTCA
Protein Sequence 
>gi|16082760|ref|NP_395206.1| secreted protein kinase [Yersinia pestis CO92] MKSVKIMGTMPPSISLAKAHERISQHWQNPVGELNIGGKRYRIIDNQVLRLNPHSGFSLFREGVGKIFSGKMFNFSIARNLTDTLHAAQKTTSQELRSDIPNALSNLFGAKPQTELPLGWKGEPLSGAPDLEGMRVAETDKFAEGESHISIIETKDKQRLVAKIERSIAEGHLFAELEAYKHIYKTAGKHPNLANVHGMAVVPYGNRKEEALLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMDENGYPIHRPGIAGVETAYTRFITDILGVSADSRPDSNEARLHEFLSDGTIDEESAKQILKDTLTGEMSPLSTDVRRITPKKLRELSDLLRTHLSSAATKQLDMGGVLSDLDTMLVALDKAEREGGVDKDQLKSFNSLILKTYRVIEDYVKGREGDTKNSSTEVSPYHRSNFMLSIVEPSLQRIQKHLDQTHSFSDIGSLVRAHKHLETLLEVLVTLSQQGQPVSSETYGFLNRLTEAKITLSQQLNTLQQQQESAKAQLSILINRSGSWADVARQSLQRFDSTRPVVKFGTEQYTAIHRQMMAAHAAITLQEVSEFTDDMRNFTVDSIPLLIQLGRSSLMDEHLVEQREKLRELTTIAERLNRLEREWM
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ypkA mutants of Y. pseudotuberculosis are attenuated in mice (Galyov et al., 1993).
COG COG0515RTKL, under R: General function prediction only; T: Signal transduction mechanisms; K: Transcription; L: Replication, recombination and repair
References
Galyov et al., 1993: Galyov EE, HÃ¥kansson S, Forsberg A, Wolf-Watz H. A secreted protein kinase of Yersinia pseudotuberculosis is an indispensable virulence determinant. Nature. 1993; 361(6414); 730-732. [PubMed: 8441468].