Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

yopB from Yersinia pestis CO92

Victor ID 1123
Gene Name yopB from Yersinia pestis CO92
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1172674
NCBI Protein GI 16082717
Locus Tag YPCD1.29c
Protein Accession NP_395163.1
Other Database IDs UniProtKB-ID: Q7ARJ0_YERPE
UniRef100: UniRef100_O68698
UniRef90: UniRef90_Q06114
UniRef50: UniRef50_Q06114
UniParc: UPI00000D607E
EMBL: AE017043
EMBL: AL117189
EMBL-CDS: AAS58573.1
EMBL-CDS: CAB54906.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_005813.1
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.29c
KEGG: ypm:YP_pCD54
HOGENOM: HBG299048
OMA: IFGWISA
ProtClustDB: CLSK862122
BioCyc: YPES214092:YPCD1.29C-MONOMER
Taxonomy ID 214092
Plasmid No pCD1
Gene Starting Position 20232
Gene Ending Position 21437
Gene Strand (Orientation) -
Protein Name secreted effector protein
DNA Sequence 
>gi|16082691:20232-21437 Yersinia pestis CO92 plasmid pCD1, complete sequence
CTTAAACAGTATGGGGTCTGCCGGCCAAATTATGCAGCATGTCACCTTTTGCATTAATCATCTGGAAAAT
CAGTTCCATCACTTGTTGATGTGACTCTGACAAATGGGATAACTCTTCTTTGAGTCGGTCAATAATACTT
TGTAACGCTGCCATGTCTGCCTTGTTCAAGGCCAAATCAGCGTTATTATGTTGTAAATCAGCTTGCTTTT
TATTATTGATGGTCTGAGTTATTCCGCTGCCCACACCAACGGCGACTTGTGTTGCCTGTGATCCTGTACG
GATTGCATGGCTCATTGTTAAACCAGCAAAACTGCCCCCTAATTTAGTCACTGCACTCCCGACAGTGTTT
GATATGCCTGTCGAAATTTGGGCAACTTTGGCCGAAAACTCGGCTCCTTTAGCCACAAGACTTGCGGTGT
TAGCACCGAGTTTTGCGCCAATATTAGCCAGGCATTTTAGTGCCGAACCGCCAAAGGTCATTACGGTTGA
AACTACAGTCAATGCGACTTCAATCGCAGTGAGTATCGGCCCTAATATTTTCATTGCCTCTTGGGATATC
AGGCCATCTTCCGCCGCTTGTTTCACTGCCATATTCGCCATCCCAATTACGCCTGAGGCAACCATCATTG
CACCGGCAACGGCTCCTACCCCTGAGGCCACCATGATGGCACCGACAATCACTGAGGCTATGGCGCTGAG
CCAGCCAAAAATCTTTGATGCGATGCCGGATTTCTTGACTTGCTTGGCATTCTCTTCTGTTTCTTTGATT
TTCTCTTGATTCTCTTCAATTTTCTTCATGTTTTGTTCATGAAGACGCTGAATATCAGCGATTTTTATGT
CTTTGCGTACTTCTTCTAAATTAGAAACTAGCTTACCTAACTCAATCTCAAATGTATCAGGTGAAGCAAG
CGTAAACTTCGTTAGCACTGAAACATAATTTGATATCAGTTGAGATCCTGCCGCGCCGCGGGTGACCGAC
TCCAATAATTTAGTGACTTCTTGCTGTTGTCCTTCAGTAACTTGGCTGGCAACCACTGCTAGTGGTGCAG
GGAGCTGTACGCCCTGAGAACTCACCCCGCCATTTTTATCCTTCAGTTCTCCCGCGACTTGTTGGGTCTG
AAGGGGGGCGGGCGCTGGTGTCTCGACGTAGGGAAGTAGACTTCCAGTTACTGGCGTTGAGCGGTCATGG
GTTATCAACGCACTCA
Protein Sequence 
>gi|16082717|ref|NP_395163.1| secreted effector protein [Yersinia pestis CO92] MSALITHDRSTPVTGSLLPYVETPAPAPLQTQQVAGELKDKNGGVSSQGVQLPAPLAVVASQVTEGQQQEVTKLLESVTRGAAGSQLISNYVSVLTKFTLASPDTFEIELGKLVSNLEEVRKDIKIADIQRLHEQNMKKIEENQEKIKETEENAKQVKKSGIASKIFGWLSAIASVIVGAIMVASGVGAVAGAMMVASGVIGMANMAVKQAAEDGLISQEAMKILGPILTAIEVALTVVSTVMTFGGSALKCLANIGAKLGANTASLVAKGAEFSAKVAQISTGISNTVGSAVTKLGGSFAGLTMSHAIRTGSQATQVAVGVGSGITQTINNKKQADLQHNNADLALNKADMAALQSIIDRLKEELSHLSESHQQVMELIFQMINAKGDMLHNLAGRPHTV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopB mutant is avirulent in mouse model, fails to elicit a cytotoxic response in cultured HeLa cells and is unable to inhibit phagocytosis by macrophage-like J774 cells (HÃ¥kansson et al., 1996).
COG COG5613S, under S: Function unknown
References
Håkansson et al., 1996: Håkansson S, Schesser K, Persson C, Galyov EE, Rosqvist R, Homblé F, Wolf-Watz H. The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity. The EMBO journal. 1996; 15(21); 5812-5823. [PubMed: 8918459].