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yopE from Yersinia pestis CO92

Victor ID 1118
Gene Name yopE from Yersinia pestis CO92
Sequence Strain (Species/Organism) Yersinia pestis CO92
NCBI Gene ID 1172651
NCBI Protein GI 16082697
Locus Tag YPCD1.06
Protein Accession NP_395143.1
Other Database IDs UniProtKB-ID: YOPE_YERPE
UniRef100: UniRef100_P31493
UniRef90: UniRef90_P31493
UniRef50: UniRef50_P31493
UniParc: UPI000013BCAD
EMBL: M34279
EMBL: AF074612
EMBL: AF053946
EMBL: AL117189
EMBL: AE017043
EMBL-CDS: AAA27672.1
EMBL-CDS: AAC69818.1
EMBL-CDS: AAC62587.1
EMBL-CDS: CAB54883.1
EMBL-CDS: AAS58592.1
RefSeq_NT: NC_003131.1
RefSeq_NT: NC_004836.1
RefSeq_NT: NC_004839.1
RefSeq_NT: NC_005813.1
PDB: 1HY5
GenomeReviews: AE017043_GR
GenomeReviews: AL117189_GR
KEGG: ype:YPCD1.06
KEGG: ypm:YP_pCD81
Taxonomy ID 214092
Plasmid No pCD1
Gene Starting Position 3599
Gene Ending Position 4258
Gene Strand (Orientation) +
Protein Name putative outer membrane virulence protein
DNA Sequence 
>gi|16082691:3599-4258 Yersinia pestis CO92 plasmid pCD1, complete sequence
CATGAAAATATCATCATTTATTTCTACATCACTGCCCCTGCCGACATCTGTGTCAGGATCTAGCAGCGTA
GGAGAAATGTCTGGGCGCTCAGTCTCACAGCAAACAAGTGATCAATATGCAAACAATCTGGCCGGGCGCA
CTGAAAGCCCTCAGGGTTCCAGCTTAGCCAGCCGTATCATTGAGAGGTTATCATCAGTGGCCCACTCTGT
GATTGGGTTTATCCAACGCATGTTCTCGGAGGGGAGCCATAAACCGGTGGTGACACCAGCACCCACACCT
GCACAAATGCCAAGTCCTACGTCTTTCAGTGACAGTATCAAGCAACTTGCTGCTGAGACGCTGCCAAAAT
ACATGCAGCAGTTGAATAGCTTGGATGCAGAGATGCTGCAGAAAAATCATGATCAGTTCGCTACGGGCAG
CGGCCCTCTTCGTGGCAGTATCACTCAATGCCAAGGGCTGATGCAGTTTTGTGGTGGGGAATTGCAAGCT
GAGGCCAGTGCCATCTTAAACACGCCTGTTTGTGGTATTCCCTTCTCGCAGTGGGGAACTATTGGTGGGG
CGGCCAGCGCGTACGTCGCCAGTGGCGTTGATCTAACGCAGGCAGCAAATGAGATCAAAGGGCTGGCGCA
ACAGATGCAGAAATTACTGTCATTGATGTG
Protein Sequence 
>gi|16082697|ref|NP_395143.1| putative outer membrane virulence protein [Yersinia pestis CO92] MKISSFISTSLPLPTSVSGSSSVGEMSGRSVSQQTSDQYANNLAGRTESPQGSSLASRIIERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQQLNSLDAEMLQKNHDQFATGSGPLRGSITQCQGLMQFCGGELQAEASAILNTPVCGIPFSQWGTIGGAASAYVASGVDLTQAANEIKGLAQQMQKLLSLM
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopE mutants are attenuated after oral or intraperitoneal infection in mice, but are not attenuated after intravenous infection in mice (Rosqvist et al., 1990).
References
Rosqvist et al., 1990: Rosqvist R, Forsberg A, Rimpiläinen M, Bergman T, Wolf-Watz H. The cytotoxic protein YopE of Yersinia obstructs the primary host defence. Molecular microbiology. 1990; 4(4); 657-667. [PubMed: 2191183].