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lysA from Brucella suis 1330

Victor ID 1108
Gene Name lysA from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1167684
NCBI Protein GI 23502831
Locus Tag BR1983
Protein Accession NP_698958.1
Other Database IDs UniProtKB-ID: Q8FYA2_BRUSU
UniRef100: UniRef100_A5VSV3
UniRef90: UniRef90_A5VSV3
UniRef50: UniRef50_Q9KVL7
UniParc: UPI00000DD755
EMBL: AE014291
EMBL-CDS: AAN30873.1
RefSeq_NT: NC_004310.3
HSSP: P31848
GenomeReviews: AE014291_GR
KEGG: bms:BR1983
TIGR: BR1983
HOGENOM: HBG672375
OMA: SIAGKCC
ProtClustDB: CLSK863778
BioCyc: BSUI204722:BR_1983-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 1909578
Gene Ending Position 1910843
Gene Strand (Orientation) +
Protein Name diaminopimelate decarboxylase
DNA Sequence 
>gi|56968325:1909578-1910843 Brucella suis 1330 chromosome I, complete sequence
CGTGAACCACTTTGAATATCGCAACGGCGTTCTCCACGCTGAAAATGTCAGCCTGCCCGAAATAGCCAAG
GCCGTCGGCACGCCTTTCTATGTCTATTCGCGCGCAACCATCGAGCGCCATTTTCGCGTGTTCCATGACG
CCTTTGCCGATATGGACACGCTCGTCACCTATGCGCTGAAGGCGAATTCCAACCAGGCTGTGCTGACGGC
GCTGGCAAAGCTTGGCGCGGGCGCGGACACGGTTTCGCAGGGCGAGATCCGCCGTGCGCTTGCCGCGGGC
ATTCCGGCAAACAGGATTGTATTTTCCGGCGTCGGCAAGACCCCGCGCGAAATGGATTTTGCGCTGGAAG
CTGGCATTTACTGTTTCAACGTCGAATCCGAGCCGGAGCTGGAAATTCTTTCAGCCCGCGCCGTCGCCGC
CGGCAAGGTGGCGCCTGTCTCGCTGCGTATCAACCCGGATGTGGATGCGAAGACCCACGCGAAAATCTCC
ACCGGCAAGTCGGAGAACAAGTTCGGCATCCCGCGCGACAAGGCGCGCGCGGCCTATGCCCGCGCGGCAA
GCCTGCCCGGCCTCAACGTCGTCGGCATCGACATGCACATCGGAAGCCAGATCATCGATCTTGAGCCTTT
CGACAATGCTTTCGCGCTGATGGCGGAACTGGTGAAGGAATTGCAGGCCGATGGCCACAATATCCGCCAT
GTCGATGTGGGCGGCGGGCTGGGCATTCCCTACCGCACCGACAACACGCCGCCGCCGCCACCTGTTGCCT
ATGCCCAAATAGTGGCGAAACACATCAAGCCGCTCGGCCTCAAGACCGTGTTTGAGCCGGGCCGCCTGAT
CGTCGGCAATGCCGGGCTTCTCGTGACGGAAGTAATTTTCGTGAAGGAAGGCGATGCGAAGAATTTCGTG
ATCGTGGACGCGGCGATGAACGATCTCATCCGCCCGACGCTTTACGATGCCTTTCACGATATCAGGCCGG
TCATTATGCCGAACGACAATGCCCCGCGCATCCGCGCCGATTTCGTCGGTCCGGTCTGCGAGACGGGCGA
CTATCTGGGCCTCGACCGCGAGGTGGCAAAGCCCGCCCCCGGCGACCTGATCGCCATCTGCACCACCGGC
GCTTATGGCGCGGTGCTTTCCAGCACCTATAACAGCCGCCTTCTCATTCCCGAAGTGCTGGTGGACGGCG
AGCGTTACCATGTGGTTCGTCCGCGCCGCACCTATGAGGAACTGCTGGCGCTCGATTCCGTGCCGGACTG
GCTGTA
Protein Sequence 
>gi|23502831|ref|NP_698958.1| diaminopimelate decarboxylase [Brucella suis 1330] MNHFEYRNGVLHAENVSLPEIAKAVGTPFYVYSRATIERHFRVFHDAFADMDTLVTYALKANSNQAVLTALAKLGAGADTVSQGEIRRALAAGIPANRIVFSGVGKTPREMDFALEAGIYCFNVESEPELEILSARAVAAGKVAPVSLRINPDVDAKTHAKISTGKSENKFGIPRDKARAAYARAASLPGLNVVGIDMHIGSQIIDLEPFDNAFALMAELVKELQADGHNIRHVDVGGGLGIPYRTDNTPPPPPVAYAQIVAKHIKPLGLKTVFEPGRLIVGNAGLLVTEVIFVKEGDAKNFVIVDAAMNDLIRPTLYDAFHDIRPVIMPNDNAPRIRADFVGPVCETGDYLGLDREVAKPAPGDLIAICTTGAYGAVLSSTYNSRLLIPEVLVDGERYHVVRPRRTYEELLALDSVPDWL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis lysA gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0019E, under E: Amino acid transport and metabolism
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].