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omp19 from Brucella suis 1330

Victor ID 1106
Gene Name omp19 from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1167630
NCBI Protein GI 23502780
Locus Tag BR1930
Protein Accession NP_698907.1
Other Database IDs UniProtKB-ID: OMP19_BRUSU
UniRef100: UniRef100_Q2YLR6
UniRef90: UniRef90_Q2YLR6
UniRef50: UniRef50_Q2YLR6
UniParc: UPI0000057B74
EMBL: AE014291
EMBL-CDS: AAN30822.1
RefSeq_NT: NC_004310.3
GenomeReviews: AE014291_GR
KEGG: bms:BR1930
TIGR: BR1930
HOGENOM: HBG348791
OMA: LAKVSAW
ProtClustDB: CLSK864010
BioCyc: BSUI204722:BR_1930-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 1863169
Gene Ending Position 1863702
Gene Strand (Orientation) -
Protein Name lipoprotein Omp19
DNA Sequence 
>gi|56968325:1863169-1863702 Brucella suis 1330 chromosome I, complete sequence
ATCAGCGCGACAGCGTCACGGCCTGCCCGCCGGTGGTCTGGCCATCGAAGCGGCCCTGTCCTGAAGAATA
GAGCGAGGCAACCGTACCGCCGTTCGCATCGTAAAGGACGAGTTGCTTGCCATTGACGGCCCAGGAGGCA
AGATTAGCCAGTTCACCGGGGCAGCGCAGCGGGCCTGCGCGATAGCCCTGGCCATATTTGGTCTGCGGCG
TCGCGATCTTGCAGCTCTGACCACCAAGCGAGGCGTTCCAGACGCCAGCCACGGCGCCGGGCGTCAGGTC
CGGTGCGGATGCAGGCGGCAGGCTTGCGACCTGTGTGCCGGATTGCGCGCTCATATCCGTGGAGGGCGCA
TTGGGGAATTGTGTGGGAGAATCAAGATTGCCTTTCTGCACCGTGCCTGCCGGAACAGCATTGACCGGTG
CAGGCGGCGGCGGAGGCGAAACATTATCGAGATTACCAAGCCGGGAGCTCTGGCACCCGGCCAGGACAAT
GCCAGCCGCCGCGAGGCTGAGCAGACTTGCTTTTGAAATTCCCA
Protein Sequence 
>gi|23502780|ref|NP_698907.1| lipoprotein Omp19 [Brucella suis 1330] MGISKASLLSLAAAGIVLAGCQSSRLGNLDNVSPPPPPAPVNAVPAGTVQKGNLDSPTQFPNAPSTDMSAQSGTQVASLPPASAPDLTPGAVAGVWNASLGGQSCKIATPQTKYGQGYRAGPLRCPGELANLASWAVNGKQLVLYDANGGTVASLYSSGQGRFDGQTTGGQAVTLSR
Molecule Role Virulence factor
Molecule Role Annotation SUBCELLULAR LOCATION: Outer membrane; lipid-anchor(UniProt: P0A3P2).

MISCELLANEOUS: Elicits an immune response in humans, mice, sheep and goats infected with B.melitensis or B.abortus, but not in B.abortus-infected cattle(UniProt: P0A3P2).

SIMILARITY: Belongs to the rhizobiaceae omp19 lipoprotein family(UniProt: P0A3P2).

MUTATION: Omp19 is an immunoreactive outer membrane lipoprotein. Significantly fewer brucellae were recovered from the spleens of mice infected with the omp19 mutant than from those of mice infected with the parent strain at 4 and 8 weeks postinfection. The omp19 mutant exhibited an increase in sensitivity to the polycation polymyxin B and to sodium deoxycholate. These results indicate that inactivation of the omp19 gene alters the outer membrane properties of B abortus (Tibor et al., 2002).
References
Tibor et al., 2002: Tibor A, Wansard V, Bielartz V, Delrue RM, Danese I, Michel P, Walravens K, Godfroid J, Letesson JJ. Effect of omp10 or omp19 deletion on Brucella abortus outer membrane properties and virulence in mice. Infection and immunity. 2002; 70(10); 5540-5546. [PubMed: 12228280].