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iroN from Escherichia coli (strain: A2363)

Victor ID 11
Gene Name iroN from Escherichia coli (strain: A2363)
Sequence Strain (Species/Organism) Escherichia coli (strain: A2363)
NCBI Gene ID 3853509
NCBI Protein GI 84060900
Locus Tag O2ColV57
Protein Accession YP_444110.1
Other Database IDs UniProtKB-ID: Q8GH18_ECOLX
UniRef100: UniRef100_Q8GH18
UniRef90: UniRef90_Q93K73
UniRef50: UniRef50_Q05098
UniParc: UPI00000BFD7B
EMBL: AF449498
EMBL: AY205565
EMBL: AY545598
EMBL: EU330199
EMBL: CP001232
EMBL: CP000836
EMBL-CDS: AAN76093.1
EMBL-CDS: AAP42474.1
EMBL-CDS: AAS80269.1
EMBL-CDS: ACA34775.1
EMBL-CDS: ACJ63531.1
EMBL-CDS: ACM18227.1
RefSeq_NT: NC_010409.1
RefSeq_NT: NC_011964.1
RefSeq_NT: NC_011980.1
RefSeq_NT: NC_007675.1
HSSP: P05825
ProtClustDB: PRK13528
Taxonomy ID 562
Plasmid No pAPEC-O2-ColV
Gene Starting Position 148716
Gene Ending Position 150893
Gene Strand (Orientation) -
Protein Name iron-related siderophore receptor; similar to GenBank Accession Number AAN76093
DNA Sequence 
>gi|84060731:148716-150893 Escherichia coli A2363 plasmid pAPEC-O2-ColV, complete sequence
ATCAGAATGATGCGGTAACTCCGGCATAGTAAGCCCGGCCTGGCTCGTTATAGGTATTCGCCCCTTCAGA
AGATCGGAAGATCTGTTTATTGAGGATATTACTGACGCCGACATTAAGACGCAGATTTTTATTAATATCG
TAATTGAAGTTCGTCCCCACCAGTGAATAAGCGCCCAGCTCTTTACCTGACAGACCGCCAGTATCTTCAC
TGCGGGTTTCCGCATGAGTACGCGGTTTTTGTCTGCCATATAACGTCCAGTTGACGCTGGCAGAAAACGC
CTGGGTGATGGTCCAGTTAAGCGAGTTATTGATAGTATATTTCGGGATGACCGACAGAGGATTACCGGTG
TCTTTTTGCTCCGAAGTGATCATCCATGTGGCATTGGTATTCCAGTTCAGACGATCTTTCACCAGTGGGA
AAGACATACTGGCTTCGATACCGTCCACCAGAGCTTTCCCGCCATTCTGCCACTTGAGGATATATGCGCC
TGAAGCGGTTTGCCCGATAACGTTATCCCCGGCCACGATCTTATTCTGGTAATCATTGCGGAAGTAGGTC
ACACTTGCGTGGTAATCTTCCCAGGTGAACTCCAGCCCAATTTCTTTATTGACGCTGATTTCCGGATCGA
GATCTTTATTACCGATCAGGTAGCACCCGCCTGATGTAATATCTTTTGGACAGCCATTGCCTTTCGAGTA
GAGCAGATAGCCTTCACTGGATTGATACAGGTTTGGAGCTTTAAAGGTTCGGGCAACCCCTGCTTTGACT
TTGAAATAATCGCCCAATTCCTGCGAAAGATTCAGACTGGGGCTGAAGTTCCCGCCGGAGTCGCTGAGAT
AATCAAAGCGCAGGCCGGGAATGATATTCGTGCCAGGAACCGGCTCAATGTTATCTTCAATATACAGCGC
ACTGATTTGAGAATGATTTTTACTGCTGCGATCCGCAGCAGAGCCAGAAATACCGCTGATATCACTGTCA
TTCACCGTCAGGCTGGTAGAGGAAGGATCATCGAGCTTATCGCGGTTCCACTCTGCACCAACGGTCAGCG
TTTGATCAACCATCACATTCAAAGGAATATTAAGCTCGCCGCTGGTTCGCCAGGAACTCAGGCGATTGGT
CGTAAACTTTTCACCCGCTAAAATACGCCCTTCACCACCGCCGGATAATCCTTCATTCATGCGGGTATTA
TTGGTTTTCTCGTAATAAACACCAAAGCGACTTTGTCCCCAGTCCCAGATACCATTATGCGTAATGCCAT
AATTCTGTCGGTACAGGCGGTTCGTCTCTTTGCCGGATTTTGCCAGGCTTTCGGTAACTGCACTGGAAGA
ACTGTTTTGCGTATCGCCCGCATAGATATTCCCCTGGCGGCTATATCCGGCTTCGAAATCGAGAATCTGC
TGCGGATTTAATTTCCACGAGACAACGCCGTTAATATCTTTGTTACGTACCCCTTCATGCCCGGCTGCGT
TTTTCGTACCGACCGGAGAATTAATATCCCAACTGTCAGCATCCGTTTTATTCAGGTTACCATACAAACG
CGTGGTAAGAGCATTACCAGCCAGAGGCCCACTAAGGCTGAAATTGGCGCGACGCGTAGCGCCCTCATCG
CTACTTTCCGGCTGATTGGTGTATAACGACAGCGAACCGTGCCAGTCGTTGGTGGGACGTTTGGTAATGA
TGTTCACCACCCCCCCGGCTGCCCCCGAACCGTAGCGCGCCGCCGCAGGGCCGCGGATCACTTCAATACG
CTCAACCTGTTCCGGTGGCACCCAGTTGGTGTCACCGCGGGTATCACGCTCTCCACGCCAGCTATAACGC
ACGGAGTTACGTGACGTCACCGGTACACCATCAATTAAAATTAAGGTGTTTTCCGGCCCCATACCACGAA
TATCGATCTGGCGGTTGTTACCGCGTGTGCCCGAGGCGCTATTGCCGGTAAGATTGACGCCAGGCATTTT
ACGAATAATATCTGAAAGGTCGTTTACCGGAGGGGTCTTTTTAATATCCTCGCTGGTAATAACCGACACG
CCCGGCTGCTGTTTTAATACCTGCTCAGCGGTGGCTTCCACCACCAGAGTCTCGTCATTATCATCGTCGG
AGGATTTGGCTACTGATACCTGGCTATTCAACCCAACCAGGAGCACAGTTAGCGACCAGAGGATTTTGTT
AATTCTCA
Protein Sequence 
>gi|84060900|ref|YP_444110.1| outer membrane receptor FepA [Escherichia coli] MRINKILWSLTVLLVGLNSQVSVAKSSDDDNDETLVVEATAEQVLKQQPGVSVITSEDIKKTPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGNALTTRLYGNLNKTDADSWDINSPVGTKNAAGHEGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGKETNRLYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILAGEKFTTNRLSSWRTSGELNIPLNVMVDQTLTVGAEWNRDKLDDPSSTSLTVNDSDISGISGSAADRSSKNHSQISALYIEDNIEPVPGTNIIPGLRFDYLSDSGGNFSPSLNLSQELGDYFKVKAGVARTFKAPNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKDLDPEISVNKEIGLEFTWEDYHASVTYFRNDYQNKIVAGDNVIGQTASGAYILKWQNGGKALVDGIEASMSFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLNWTITQAFSASVNWTLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNILNKQIFRSSEGANTYNEPGRAYYAGVTASF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iroA gene cluster mutants were unable to resist Lcn2 in mouse serum (Fischbach et al., 2006).
References
Fischbach et al., 2006: Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, Aderem A, Smith KD. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(44); 16502-16507. [PubMed: 17060628].