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aspC from Brucella suis 1330

Victor ID 1091
Gene Name aspC from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1167178
NCBI Protein GI 23502364
Locus Tag BR1495
Protein Accession NP_698491.1
Other Database IDs UniProtKB-ID: Q8FZI6_BRUSU
UniRef100: UniRef100_Q8FZI6
UniRef90: UniRef90_A6WZI4
UniRef50: UniRef50_P58350
UniParc: UPI00000DD5E9
EMBL: AE014291
EMBL-CDS: AAN30406.1
RefSeq_NT: NC_004310.3
HSSP: Q56232
GenomeReviews: AE014291_GR
KEGG: bms:BR1495
NMPDR: fig|204722.1.peg.1448
TIGR: BR1495
HOGENOM: HBG645860
OMA: IGKTAPS
ProtClustDB: PRK05764
BioCyc: BSUI204722:BR_1495-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 1451722
Gene Ending Position 1452924
Gene Strand (Orientation) +
Protein Name aspartate aminotransferase
DNA Sequence 
>gi|56968325:1451722-1452924 Brucella suis 1330 chromosome I, complete sequence
CATGGCATTTCTCGCCGACGCCCTTTCCCGTGTAAAGCCATCTGCGACCATCGCTGTCAGCCAGAAAGCA
CGTGAACTGAAAGCAAAAGGCAAGGACGTGATCGTCCTGGGCGCAGGTGAGCCGGATTTCGACACGCCTG
AAAATATCAAGCAGGCGGCCATTGCCGCGATCAATCGCGGTGAAACAAAGTACACGCCCGTATCCGGCAT
CCCGCAACTGCGCCAGGCCATCGTCTCCAAGTTCAAGCGTGAAAACGGCCTCGACTACAAGCCGGAACAG
ACCATCGTCGGCACCGGCGGCAAGCAGATTTTGTTCAACGCCTTCATGGCCACGCTGAACCCCGGCGACG
AAGTCATCATTCCCGCCCCCTATTGGGTCAGCTACCCGGAAATGGTGGCCATCAACGGCGGCACCCCGGT
TTTCATCGACACGAAGATTGAAGACAATTTCAAGCTGACCGCTGCCGATCTCGAAAAGGCGATCACACCG
AAGACCAAGTGGCTCATCTTCAACTCGCCCTCCAACCCGACCGGCGCGGCCTATACGCAAGCCGAACTGA
AGTCGCTGACCGACGTTCTCGTGCGCCATCCGCATGTCTGGATCTTGACCGACGACATGTATGAGCATCT
GGTCTATGGCGATTTCGTCTTCACGACGCCTGCTCAGGTGGAACCCTCGCTCTATGACCGTACGCTCACC
ATGAACGGCGTTTCCAAGGCCTATGCCATGACCGGCTGGCGCATCGGCTATGCCGCCGGTCCAATCGAGC
TCATCAAGGCCATGGACATGATTCAGGGGCAGCAGACCTCCGGCGCCTGCTCGATTGCTCAGTGGGCAGC
GGTCGAAGCACTGAACGGCACGCAGGATTTCATCCCCGCGAACAAGAAAATCTTCCAGGCCCGCCGCGAT
CTGGTCGTTTCCATGCTCAACCAGGCAACCGGCCTCCAGTGCCCGACGCCGGAAGGCGCGTTCTATGTCT
ATCCGTCCTGCGCAGGGCTGATCGGCAAGAAGACCGAAGCGGGCAAAGTCATCGAAACCGACAAAGATTT
CGTGACGGAACTTCTGGAAACCGAAGGCGTGGCGGTTGTTCATGGTTCGGCATTCGGCCTCGGCCCGAAC
TTCCGCATTTCCTATGCAACCTCGGATGAGCTGCTGGAAAAAGCCTGCATACGCATCCAGCGTTTCTGCG
CCAGCCTGCGCTG
Protein Sequence 
>gi|23502364|ref|NP_698491.1| aspartate aminotransferase [Brucella suis 1330] MAFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRGETKYTPVSGIPQLRQAIVSKFKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIPAPYWVSYPEMVAINGGTPVFIDTKIEDNFKLTAADLEKAITPKTKWLIFNSPSNPTGAAYTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKAYAMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQARRDLVVSMLNQATGLQCPTPEGAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGVAVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aspC encodes for an aminotransferase. B.abortus aspC mutant obtained from randomized miniTn5Km2 transposon mutagenesis showed decreased intracellular survival inside HeLa cells. So B. abortus aspC gene is essential for HeLa cell intracellular growth (Kim et al., 2003).
COG COG0436E, under E: Amino acid transport and metabolism
References
Kim et al., 2003: Kim S, Watarai M, Kondo Y, Erdenebaatar J, Makino S, Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infection and immunity. 2003; 71(6); 3020-3027. [PubMed: 12761078].