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nirA

Victor ID 108
Gene Name nirA
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885472
NCBI Protein GI 15609528
Locus Tag Rv2391
Protein Accession NP_216907.1
Other Database IDs UniProtKB-ID: SIR_MYCTU
UniRef100: UniRef100_Q7TYP6
UniRef90: UniRef90_Q7TYP6
UniRef50: UniRef50_Q7TYP6
UniParc: UPI00001650F5
EMBL: BX842579
EMBL: AE000516
EMBL-CDS: CAB03734.1
EMBL-CDS: AAK46756.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 1ZJ8
PDB: 1ZJ9
EnsemblGenome: EBMYCG00000002064
EnsemblGenome_TRS: EBMYCT00000002066
EnsemblGenome_PRO: EBMYCP00000002066
EnsemblGenome: EBMYCG00000071196
EnsemblGenome_TRS: EBMYCT00000071201
EnsemblGenome_PRO: EBMYCP00000069260
GenomeReviews: AE0005
Taxonomy ID 83332
Gene Starting Position 2684678
Gene Ending Position 2686369
Gene Strand (Orientation) +
Protein Name PROBABLE FERREDOXIN-DEPENDENT NITRITE REDUCTASE NIRA
DNA Sequence 
>gi|57116681:2684678-2686369 Mycobacterium tuberculosis H37Rv, complete genome
GATGTCCGCGAAGGAGAACCCCCAAATGACCACTGCACGTCCCGCCAAGGCTCGAAATGAGGGCCAGTGG
GCGCTGGGACATCGCGAGCCACTCAACGCCAACGAAGAGCTGAAGAAGGCCGGCAACCCGCTCGACGTGC
GGGAGCGCATCGAAAACATCTACGCCAAACAGGGTTTCGACAGCATCGACAAGACCGACCTGCGAGGGCG
CTTTCGCTGGTGGGGCCTGTACACCCAGCGTGAGCAGGGCTACGACGGCACCTGGACCGGTGACGACAAC
ATCGACAAGCTCGAGGCCAAATACTTCATGATGCGGGTGCGTTGCGACGGCGGCGCGCTCTCGGCTGCCG
CGCTGCGCACGCTGGGCCAGATCTCGACGGAGTTCGCGCGCGATACCGCCGATATCTCCGACCGGCAGAA
CGTGCAATACCACTGGATCGAAGTGGAAAACGTCCCTGAAATCTGGCGACGGTTAGACGATGTCGGACTG
CAGACCACCGAGGCGTGCGGTGACTGCCCGCGGGTAGTGCTGGGCTCGCCGTTGGCCGGCGAGTCGCTCG
ACGAAGTGCTCGACCCGACCTGGGCGATCGAGGAGATCGTGCGTCGCTACATCGGCAAGCCCGACTTCGC
CGACTTGCCGCGCAAGTACAAGACCGCCATCTCTGGCCTGCAGGACGTCGCGCACGAGATCAACGACGTC
GCCTTCATCGGCGTCAACCATCCCGAGCACGGACCAGGCCTGGATCTGTGGGTGGGCGGTGGACTGTCGA
CCAACCCGATGCTGGCCCAGCGGGTCGGCGCCTGGGTTCCACTGGGCGAAGTGCCCGAGGTGTGGGCGGC
GGTCACCTCGGTGTTTCGCGACTACGGCTACCGGCGACTGCGCGCCAAGGCCCGGCTGAAATTTCTGATC
AAAGACTGGGGCATAGCGAAGTTCCGCGAAGTGCTCGAAACCGAGTACCTCAAGCGTCCGCTGATCGACG
GTCCGGCCCCCGAACCGGTCAAGCATCCGATCGACCACGTCGGGGTGCAACGACTCAAGAACGGGCTCAA
CGCCGTCGGAGTCGCCCCCATCGCCGGGCGGGTATCGGGCACCATCCTCACGGCGGTCGCCGACCTGATG
GCGCGGGCCGGTTCCGACCGGATCCGGTTCACCCCCTACCAGAAGCTGGTCATCCTCGACATTCCGGACG
CCTTGCTCGACGACTTGATCGCCGGTCTGGACGCGCTGGGGCTGCAGTCGCGCCCGTCGCATTGGCGCCG
GAACTTGATGGCGTGCAGCGGGATTGAGTTCTGCAAGTTGTCATTCGCCGAAACCCGGGTTCGAGCACAG
CATTTGGTGCCCGAGCTGGAACGCCGGCTTGAGGACATCAACTCGCAGCTCGACGTACCGATCACCGTCA
ACATCAACGGCTGCCCGAACTCATGTGCGCGAATTCAAATCGCCGACATCGGATTCAAGGGACAGATGAT
CGACGACGGACACGGCGGCTCCGTCGAAGGCTTCCAGGTGCATCTGGGCGGACACCTCGGCCTGGATGCC
GGATTCGGCCGCAAACTGCGCCAGCACAAGGTCACCAGTGACGAACTCGGCGACTACATCGACCGGGTGG
TGCGCAACTTCGTCAAACACCGCAGCGAAGGTGAACGCTTCGCGCAGTGGGTCATCCGGGCCGAGGAGGA
CGACCTGCGATG
Protein Sequence 
>gi|15609528|ref|NP_216907.1| sulfite reductase [Mycobacterium tuberculosis H37Rv] MSAKENPQMTTARPAKARNEGQWALGHREPLNANEELKKAGNPLDVRERIENIYAKQGFDSIDKTDLRGRFRWWGLYTQREQGYDGTWTGDDNIDKLEAKYFMMRVRCDGGALSAAALRTLGQISTEFARDTADISDRQNVQYHWIEVENVPEIWRRLDDVGLQTTEACGDCPRVVLGSPLAGESLDEVLDPTWAIEEIVRRYIGKPDFADLPRKYKTAISGLQDVAHEINDVAFIGVNHPEHGPGLDLWVGGGLSTNPMLAQRVGAWVPLGEVPEVWAAVTSVFRDYGYRRLRAKARLKFLIKDWGIAKFREVLETEYLKRPLIDGPAPEPVKHPIDHVGVQRLKNGLNAVGVAPIAGRVSGTILTAVADLMARAGSDRIRFTPYQKLVILDIPDALLDDLIAGLDALGLQSRPSHWRRNLMACSGIEFCKLSFAETRVRAQHLVPELERRLEDINSQLDVPITVNINGCPNSCARIQIADIGFKGQMIDDGHGGSVEGFQVHLGGHLGLDAGFGRKLRQHKVTSDELGDYIDRVVRNFVKHRSEGERFAQWVIRAEEDDLR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0155P, under P: Inorganic ion transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].