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ntrY from Brucella suis 1330

Victor ID 1077
Gene Name ntrY from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166792
NCBI Protein GI 23501994
Locus Tag BR1116
Protein Accession NP_698121.1
Other Database IDs UniProtKB-ID: Q8G0H8_BRUSU
UniRef100: UniRef100_A9M5C9
UniRef90: UniRef90_A9M5C9
UniRef50: UniRef50_A5VQP0
UniParc: UPI00000DD4CE
EMBL: AE014291
EMBL-CDS: AAN30036.1
RefSeq_NT: NC_004310.3
HSSP: P02933
GenomeReviews: AE014291_GR
KEGG: bms:BR1116
TIGR: BR1116
HOGENOM: HBG311288
OMA: RIVRPIR
ProtClustDB: CLSK862978
BioCyc: BSUI204722:BR_1116-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 1092084
Gene Ending Position 1094408
Gene Strand (Orientation) -
Protein Name nitrogen regulation protein NtrY
DNA Sequence 
>gi|56968325:1092084-1094408 Brucella suis 1330 chromosome I, complete sequence
ATCAAATCACCTGTCCAGCTGTGTGCTTTTCGTCATTTCCCGAATCCGCATCGGATGGAATGGGGGGATC
CTCGGGAAAGACCATACGTATCATTGCGCCCCGGCCTGCGTGAAAATCCGCGGGCGCATCATGCAATTCA
AGATTACCGCCATGATCTTCAACAATCTTGCGAACGATTGCGAGGCCAAGGCCCGTTCCCTTTTCGCGGG
TCGTCATATAGGGTTCCAGCAGTTTCTGGCGATCATCGCCGGGCAAGCCCTTGCCGTTGTCGATCACATC
GACCACCAGTTGCCCATCCGCCCTGTAGGCGTGAATGCGGATATGCCCCTCGCCGCGCTCTTCCTTCGCA
ACCGCGTCAATGGCCTCGCTGGCATTCTTGATGACATTGCCGAAGGCCTGCCCGATCAGGCGGCTATCGA
ACGATCCAATCAGCTTTTCCGAACCGAAATCATTGTCGAAATGAATGTCGCTGCGGCTGACTTCAATCAG
GAACGAGGCTTCACGCAATGCTTCGCGCAGGTCCATATGCCGCATTTCCGGCTTGGGCATACGCGCAAAA
GCGGAGAACTCATCGACCATGCGGCCAATATCGCCGACCTGACGAATGATGGTGTCCGTGCACTGGTCGA
AAACCTCGCGATCCTCCGTGATGACCTTGCCATACCGGCGGCGGATGCGCTCTGCCGAAAGCTGGATCGG
CGTCAGCGGATTCTTGATTTCATGCGCGATGCGCCGCGCCACATCCGCCCATGCGGAAGAACGTTGCGCC
TGCACCAGATCGGTGATGTCGTCCACCGTCACCACATAGGAGTGATCCTCGGATTCGGCATCCTCGACCG
TTACCTGCACATTGAAGCTGCGGCTACCGCCGCCGCGCGCCATGCTCACCTGCTCGCGGTGCACGGTTCG
CCCCGTGGCGCGCGCCACCTCGAAAGCCTGCCCGACCTCCGGCGCGATGCTGGTAAGGCTTTTCCCGACC
GCATCTTCCGACGTTACGCCAAACATATGCTCCGCAGAGCGGTTGAGGATCGAAATCGACCCGTCATTCT
CAATACCGATAACCCCTGCCGTCACACCCGAAAGCACGGCTTCGGAGAAGCGGCGGCGCTCATCGATCTG
GTCCTTGGCGGAAATAAGTTCGTTGCGCTGGCTTTTCAGCTCGGCAACCATGTTGTTGAAAGTACCCGAC
AGCGCCCCCACATCGCCATCGGACGAGCGCACCGGCACCGAAACATCAAGATTGCCGGCAGCCACATCGT
CCGATGCGCCGATCAGCAGCCGGATTGGCCGCACCAGCCGGTCTGCAACGGCAATGCCCGTCCAGATGGC
CGACAGAAGCACGATCAGCGTCAGGCCGAAATAGAGCAAAGCGAAAGCAATCTGCGTCGGAATGCGGTTC
GCATCCATTTCCTGATAGCGCCTGGCATTGGCATTCATCAGATTGATGGCATCAAGAATTTGCGGCGGAA
CCGAACGCACCGTATAAAGATACATGTCGGGAATTTCGCGCATCTTGATGAGTGCACCGACGAAATTGGT
GTTTCCCGGCGGGATGATGACAGGCTTTCCGTCCGGTGCCTTTTCAAGCGAATCCTTCGTCGGCGGCGGC
AGATGGCTTTCCATGCCCGTATCGCTCTGCACGACGACATCGCCATTATCACGCACCAGAAATGCGCCCA
GCAAGGCGCGCCCACGCACCTGCAATGTCATCAACTGGATGAAACCGTTCCGGTCGAGGCTATAAATGGC
ACGCTGCGCATCCAGATCCTGCAACATCGAATAGGACGTGCTCTGGAGGTTCAACGCGGTTTCCTGAAGA
TAGGCTGTATAGAAATTCTGGGATGAACTGATGATGTCGCGTGTATTCTGGTCGAACCAGCGATCAAGGC
CCAGATTGAGGGTCACGGAAGCGACAATTGCCACCACGATTGCCGGAATGGCGGCAATCAGCGAAAACAG
GGCTACAATGCGCACATGCAGGCGCGACGCGGCCTTGCCCAGCCTGCGCGCCGTTATGATGCGATAGACC
TCGCGGCAGATCAGCAGGATCAGAAACAAAATCAACGCGACATTGATAATCACCAGCGCCAGTGTAACCG
TGCGGTCGGGGGTGATTGGCGTAATACCGATCAGGATCGCGAAGGAAAACGAAGCTGTGACCAGCGCCGA
AACGACGGTAATAATACCCGGTAAGGCGAGAAGCCTGCGCCCCTCACCCTGCCCCTCATCTTGCGATGAT
TGCCTCGTCCCATTCATGTCGGTCGTCAGATTCGCCCTGTTCATGTTAACCATAATAACCAATAGCGTTG
CATCTATGCAACGCA
Protein Sequence 
>gi|23501994|ref|NP_698121.1| nitrogen regulation protein NtrY [Brucella suis 1330] MRCIDATLLVIMVNMNRANLTTDMNGTRQSSQDEGQGEGRRLLALPGIITVVSALVTASFSFAILIGITPITPDRTVTLALVIINVALILFLILLICREVYRIITARRLGKAASRLHVRIVALFSLIAAIPAIVVAIVASVTLNLGLDRWFDQNTRDIISSSQNFYTAYLQETALNLQSTSYSMLQDLDAQRAIYSLDRNGFIQLMTLQVRGRALLGAFLVRDNGDVVVQSDTGMESHLPPPTKDSLEKAPDGKPVIIPPGNTNFVGALIKMREIPDMYLYTVRSVPPQILDAINLMNANARRYQEMDANRIPTQIAFALLYFGLTLIVLLSAIWTGIAVADRLVRPIRLLIGASDDVAAGNLDVSVPVRSSDGDVGALSGTFNNMVAELKSQRNELISAKDQIDERRRFSEAVLSGVTAGVIGIENDGSISILNRSAEHMFGVTSEDAVGKSLTSIAPEVGQAFEVARATGRTVHREQVSMARGGGSRSFNVQVTVEDAESEDHSYVVTVDDITDLVQAQRSSAWADVARRIAHEIKNPLTPIQLSAERIRRRYGKVITEDREVFDQCTDTIIRQVGDIGRMVDEFSAFARMPKPEMRHMDLREALREASFLIEVSRSDIHFDNDFGSEKLIGSFDSRLIGQAFGNVIKNASEAIDAVAKEERGEGHIRIHAYRADGQLVVDVIDNGKGLPGDDRQKLLEPYMTTREKGTGLGLAIVRKIVEDHGGNLELHDAPADFHAGRGAMIRMVFPEDPPIPSDADSGNDEKHTAGQVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The NtrY protein is a sensor of an ntr-related regulon which may be part of the glnALG operon. This mutant has a weakly attenuated phenotype (reduction of 1.2 log units versus the wild type at 48 h postinfection) which could be explained by a pleiotropic effect on the ntr regulon, since the ntrC mutant did not show such a phenotype (Foulongne et al., 2000).
COG COG5000T, under T: Signal transduction mechanisms
References
Foulongne et al., 2000: Foulongne V, Bourg G, Cazevieille C, Michaux-Charachon S, O'Callaghan D. Identification of Brucella suis genes affecting intracellular survival in an in vitro human macrophage infection model by signature-tagged transposon mutagenesis. Infection and immunity. 2000; 68(3); 1297-1303. [PubMed: 10678941].