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glnA from Brucella suis 1330

Victor ID 1071
Gene Name glnA from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166677
NCBI Protein GI 23501884
Locus Tag BR1004
Protein Accession NP_698011.1
Other Database IDs UniProtKB-ID: Q8G0T3_BRUSU
UniRef100: UniRef100_A9MB20
UniRef90: UniRef90_A9MB20
UniRef50: UniRef50_P00964
UniParc: UPI00000DD474
EMBL: AE014291
EMBL-CDS: AAN29926.1
RefSeq_NT: NC_004310.3
HSSP: P06201
GenomeReviews: AE014291_GR
KEGG: bms:BR1004
NMPDR: fig|204722.1.peg.968
TIGR: BR1004
HOGENOM: HBG553755
OMA: FAEGTMF
ProtClustDB: CLSK862961
BioCyc: BSUI204722:BR_1004-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 967119
Gene Ending Position 968528
Gene Strand (Orientation) -
Protein Name glutamine synthetase, type I
DNA Sequence 
>gi|56968325:967119-968528 Brucella suis 1330 chromosome I, complete sequence
TTTATACCGAGTAATACATATCGAACTCGACCGGGTGCGGCGTCATTTCAAAACGCATCACTTCAGCCAT
TTTCAGCTCGATGAAGCTGTCGATCTGGTCGTCGGAGAACACGCCGCCAGCCTTGAGGAATTCACGATCC
TTGTCGAGCGACTGTAGAGCTTCACGCAGGGAGCCGCAGACGGTCGGAATCTGCTTCAGTTCCTTCGGCG
GCAGGTCGTAGAGATCCTTGTCCATGGCCTGGCCCGGATGGATCTTGTTCTTGATGCCGTCAAGGCCCGC
CATCAGAAGGGCCGAGAAGCAGAGATAAGGGTTGGCGGACGGATCCGGGAAGCGGACTTCGAGACGCTTC
GATTTCGGCGAGGAGCCGAATGGAATGCGGCAGGAAGCCGAACGGTTGCGTGCGGAATAGGCCAGCAGAA
CAGGCGCTTCATAGCCCGGCACCAGACGCTTGTAGGAGTTGGTGGACGGGTTGGTGAAGGCATTCACAGC
TTTTGCGTGCTTGATGACGCCGCCAATGAAGTAGAGGCAGTTTTCCGACAGACCAGCATATTCATTGCCT
GCGAAGGTCGGCTTGCCGTCTTTCCAGATCGAGAAGTGAACATGCATGCCGGAGCCATTGTCGCCAAAGA
CCGGCTTCGGCATGAAGGTTGCCGTTTTGCCATAGGCATTGGCAACCTGATGCACGACATATTTCTGAAT
CTGCATCTTGTCGGCGTTGCGCACCAGCGTGTCGAATTTCGTGCCCAGTTCGTGCTGCGCGGAAGCGACT
TCATGGTGGTGCTTTTCAACCGTCACACCCATTTCCGAGAGCACGGTCAGCATTTCGGAACGCATGTCCT
GCAAGCTGTCGATTGGCGGAACGGGGAAATAGCCGCCCTTGACGCGCGGACGATGGCCGAGATTGCCGGT
TTCATAATCGGTGTCGTCGTTGGATGGCAATTCGGCGCTATCGAGCTTGAAGCCCGTATTGAACGGATCG
GCCTTGAACTTCACATCGTCGAAGACGAAGAATTCGGCTTCCGGGCCGACATAGACCGTATCGCCAATGC
CGAGCGATTTCAGATAGGCTTCGGCCTTCTTGGCAGTCGTACGCGGATCACGGCTGTAGCTTTCGCCGGA
AAGCGGCTCAAGGATATCGCAGAGAATGACAAGCGTGGACTGGGCGAAGAACGGGTCGATATGAGCCGTT
TCCGGATCGGGCATCAAAACCATGTCGGATTCGTTGATGGCCTTCCAGCCTGCGATCGAAGAGCCGTCGA
ACATGACACCGTCGACGAACATGTCTTCGTCCACGAGGCCGATATCCATCGTAACGTGATGGAGCTTGCC
CTTCGGATCGGTGAAGCGAAGGTCGACGAACTTGACGTCGTTATCTTTGATCTGTTTCAGAATATCGTTG
GCAGTCGTCA
Protein Sequence 
>gi|23501884|ref|NP_698011.1| glutamine synthetase [Brucella suis 1330] MTTANDILKQIKDNDVKFVDLRFTDPKGKLHHVTMDIGLVDEDMFVDGVMFDGSSIAGWKAINESDMVLMPDPETAHIDPFFAQSTLVILCDILEPLSGESYSRDPRTTAKKAEAYLKSLGIGDTVYVGPEAEFFVFDDVKFKADPFNTGFKLDSAELPSNDDTDYETGNLGHRPRVKGGYFPVPPIDSLQDMRSEMLTVLSEMGVTVEKHHHEVASAQHELGTKFDTLVRNADKMQIQKYVVHQVANAYGKTATFMPKPVFGDNGSGMHVHFSIWKDGKPTFAGNEYAGLSENCLYFIGGVIKHAKAVNAFTNPSTNSYKRLVPGYEAPVLLAYSARNRSASCRIPFGSSPKSKRLEVRFPDPSANPYLCFSALLMAGLDGIKNKIHPGQAMDKDLYDLPPKELKQIPTVCGSLREALQSLDKDREFLKAGGVFSDDQIDSFIELKMAEVMRFEMTPHPVEFDMYYSV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis glnA gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0174E, under E: Amino acid transport and metabolism
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].