Victors

panC from Mycobacterium tuberculosis H37Rv
Victor ID	107
Gene Name	panC from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism)	Mycobacterium tuberculosis H37Rv
NCBI Gene ID	885459
NCBI Protein GI	15610738
Locus Tag	Rv3602c
Protein Accession	NP_218119.1
Other Database IDs	UniProtKB-ID: PANC_MYCTU UniRef100: UniRef100_A1KPT7 UniRef90: UniRef90_A1KPT7 UniRef50: UniRef50_A0PV50 UniParc: UPI000013129B EMBL: BX842583 EMBL: AE000516 EMBL-CDS: CAB08942.1 EMBL-CDS: AAK48065.1 RefSeq_NT: NC_000962.2 RefSeq_NT: NC_002755.2 PDB: 1MOP PDB: 1N2B PDB: 1N2E PDB: 1N2G PDB: 1N2H PDB: 1N2I PDB: 1N2J PDB: 1N2O PDB: 2A7X PDB: 2A84 PDB: 2A86 PDB: 2A88 PDB: 3COV PDB: 3COW PDB: 3COY PDB: 3COZ PDB: 3IMC PDB: 3IME PDB: 3IMG PDB: 3IOB PDB: 3IOC PDB: 3IOD PDB: 3IOE PDB: 3ISJ PDB: 3IUB PDB:
Taxonomy ID	83332
Gene Starting Position	4044280
Gene Ending Position	4045209
Gene Strand (Orientation)	-
Protein Name	pantoate--beta-alanine ligase
DNA Sequence	>gi\|57116681:4044280-4045209 Mycobacterium tuberculosis H37Rv, complete genome ATCAGTTTCTCCAATGTGATTCGAGGATTGCCCGGTATCCGTCCGGGCGGTCGGTGCCGGCGAAAGTTCC GATTTCAATCGCAATGTTGTCCAGCAGCCTGGTGGTGCCAAGCCGGGCAGCAACCAGCAGCCGACCGGAA CCGTTGAGCGGCATCGGGCCAAGCCCGATATCGCGCAGCTCCAGGTAGTCGACCGCCACGCCGGGTGCAG CGTCGAGCACCGCACGGGCGGCATCCAGCGCGGCCTGCGCGCCAGCCGTTGCCGCATGCGCTGCGGCCGT TAGCGCCGCCGAGAGCGCGACGGCCGCCGCACGCTGGGCCGGGTCCAGGTAGCGGTTGCGCGACGACATC GCCAGCCCGTCGGCTTCGCGCACGGTCGGCACGCCGACCACCGCGACATCGAGGTTGAAGTCCGCGACCA GCTGCCGGATCAGCACCAGCTGCTGGTAGTCCTTCTCACCGAAGAACACCCGATCCGGGCGCACGATCTG CAGCAGCTTTAGCACGACCGTCAGCACGCCGGCGAAATGGGTTGGCCGCGGGCCGCCCTCGAGTTCGGCG GCCAACGGACCGGGTTGCACGGTGGTGCGCAGGCCGTCGGGATACATCGCCGCGGTAGTTGGCGTGAAAG CGATTTCCACGCCTTCGGCCCGCAGTTGCGCCAGGTCGTCGTCCGGGGTGCGGGGATAGGCGTCGAGATC TTCCCCGGCACCGAATTGCATCGGGTTGACGAAGATCGACACGACGACGACCGATCCGGGCACCCGCTTG GCCGCACGCACCAACGCGAGGTGGCCTTCGTGCAGCGCACCCATAGTAGGCACCAACATCACTCGCCGGC CGGTGAGTCGCAGTGCGCGACTGACATCGGCGACATCCCCCGGTGCCGAGTACACATTGAGTTCACCGGG ATGGAACGCAGGAATCGTCA
Protein Sequence	>gi\|15610738\|ref\|NP_218119.1\| pantothenate synthetase [Mycobacterium tuberculosis H37Rv] MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYRAILESHWRN
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: panCD mutant is attenuated in mice (Sambandamurthy et al., 2002).
COG	COG0414H, under H: Coenzyme transport and metabolism
References	*Sambandamurthy et al., 2002:* Sambandamurthy VK, Wang X, Chen B, Russell RG, Derrick S, Collins FM, Morris SL, Jacobs WR Jr. A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis. Nature medicine. 2002; 8(10); 1171-1174. [PubMed: 12219086].


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panC from Mycobacterium tuberculosis H37Rv