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tig from Brucella suis 1330

Victor ID 1064
Gene Name tig from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166567
NCBI Protein GI 23501784
Locus Tag BR0898
Protein Accession NP_697911.1
Other Database IDs UniProtKB-ID: TIG_BRUSU
UniRef100: UniRef100_Q8G129
UniRef90: UniRef90_B2S5D1
UniRef50: UniRef50_B2S5D1
UniParc: UPI000021CADD
EMBL: AE014291
EMBL-CDS: AAN29826.1
RefSeq_NT: NC_004310.3
GenomeReviews: AE014291_GR
KEGG: bms:BR0898
NMPDR: fig|204722.1.peg.868
TIGR: BR0898
HOGENOM: HBG635105
ProtClustDB: PRK01490
BioCyc: BSUI204722:BR_0898-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 871530
Gene Ending Position 872987
Gene Strand (Orientation) +
Protein Name trigger factor
DNA Sequence 
>gi|56968325:871530-872987 Brucella suis 1330 chromosome I, complete sequence
AATGACAAGAAGTGAAGGTTTGAACATGCAGGTTACCGAAACGCTCAATGAAGGGCTGAAGCGCGAGATC
AAAGTCGTGGTTCCGGCCGGGGATCTTGAAGCCAAGCTCGCTGAGCGGCTCGAAACCGCGCGCGGCCGCG
CCCGCATCAACGGCTTCCGTCCGGGCAAGGTGCCGACGGCTCACCTGCGCAAGATGTACGGCAAGTCCTT
CATGGCCGAGATCGTCAACGAAATCCTCAACGATTTGTCGCGTTCCATCCTTGCCGAACGCAACGAAAAG
TCGGCGACCCAGCCTGAAGTCATCATGTCGGAAGACGAAAAAGAAGCCGAGAAGGTTCTCGACGGCAAGG
CCGATTTCGTTTTCTCGCTGAACTATGAAGTGCTGCCGGCAATCGAGGTCAAGGACTTCTCCAAGATCGC
CGTGACCCGTGAAGTCGTCGACATTTCCGATGAGGAAGTCGATGAACAGGTCAAGCGCATTGCGTCGTCG
ACCCGCACCTTTGAAACCAAGAAGGGCAAGGCCGAAAACGAAGATCGCGTCACGATCGACTATCTGGGCA
AGCTCGACGGCGAGCCGTTTGAAGGCGGTGCAGACAATGACGCACAGCTCGTTCTCGGTTCCGGCCAGTT
CATTCCGGGCTTTGAAGAACAGCTCATTGGTTTGAAGGCTGGCGACGAGAAGGTCATCACCGTAACGTTC
CCGGCTGAATACGGCGCTGCGCATCTGGCTGGCAAGGAAGCAACCTTCGACATCAAGGTGAAGGAAGTTG
CCAAGCCGAACGAACTCGTTCTCGATGACGAAACCGCAAAGAAGCTCGGCATTGAGTCGCTTGAGCGTCT
GCGTCAGGTTGTGCGCGAACAGATCGAAAGCCAGTACGGCCAGGTCACCCGCCAGAAAGTGAAGCGTCAG
ATTCTCGACGCCCTTGATGGTGATTATCAGTTTGAAACCCCGCAGAAGCTGGTTGACGCCGAGTTCAACA
ACATCTGGCAGCAGATCAACTTCGACCTGCAGCAGGCTGGCCGCACTTTTGAAGACGAGGAAACGACGGA
AGAAGCTGCTCGCGAAGAATATCGCAAGCTTGCAGAACGCCGCGTTCGTCTTGGCCTCGTTCTCTCCGAA
ATCGGCGAGAAGGCAGGCGTGGAAGTGACCGAAGAAGAACTGCAGCGCGCTGTTTACGATCAGGTTCGCC
GCTATCCGGATCAGGAAAAGGAAATCTACGACTTCCTGCGCCGTACGCCGGATGCCGTCGCCAATCTGCG
CGCGCCGATCTTTGAAGAAAAGGTCGTCGATCATCTGCTGGCCAACATCAATGTGACCGACAAGAAGGTC
TCGAAGGAAGAGCTGACGGCTGAAGACGAAGATGCAGCTTCGGAAGCAAAGCCTGCCAAGAAGGCGGCTG
CGAAGAAGAAGGCTGCGCCGAAGAAGAAGGCCGAAGAAGGCAAGTCCGAAGAGGCTTG
Protein Sequence 
>gi|23501784|ref|NP_697911.1| trigger factor [Brucella suis 1330] MTRSEGLNMQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTAHLRKMYGKSFMAEIVNEILNDLSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFVFSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRIASSTRTFETKKGKAENEDRVTIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAAHLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQVTRQKVKRQILDALDGDYQFETPQKLVDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKLAERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPDQEKEIYDFLRRTPDAVANLRAPIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEGKSEEA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTION: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation (By similarity)(UniProt: Q8G129).

SIMILARITY: Belongs to the FKBP-type PPIase family. Tig subfamily(UniProt: Q8G129).

SIMILARITY: Contains 1 PPIase FKBP-type domain(UniProt: Q8G129).

MUTATION: tig encodes for Trigger factor that helps protein folding and secretion. It is one of the attenuated Signature-Tagged Mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice (Lestrate et al., 2003).
COG COG0544O, under O: Posttranslational modification, protein turnover, chaperones
References
Lestrate et al., 2003: Lestrate P, Dricot A, Delrue RM, Lambert C, Martinelli V, De Bolle X, Letesson JJ, Tibor A. Attenuated signature-tagged mutagenesis mutants of Brucella melitensis identified during the acute phase of infection in mice. Infection and immunity. 2003; 71(12); 7053-7060. [PubMed: 14638795].