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spotT from Brucella suis 1330

Victor ID 1057
Gene Name spotT from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166315
NCBI Protein GI 23501539
Locus Tag BR0652
Protein Accession NP_697666.1
Other Database IDs UniProtKB-ID: RSH_BRUSU
UniRef100: UniRef100_Q8CY42
UniRef90: UniRef90_A5VPI9
UniRef50: UniRef50_A5VPI9
UniParc: UPI00000E4796
EMBL: AE014291
EMBL-CDS: AAN29581.1
RefSeq_NT: NC_004310.3
HSSP: Q54089
GenomeReviews: AE014291_GR
KEGG: bms:BR0652
NMPDR: fig|204722.1.peg.623
TIGR: BR0652
HOGENOM: HBG594146
OMA: ADIGPIR
ProtClustDB: CLSK864835
BioCyc: BSUI204722:BR_0652-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 642066
Gene Ending Position 644318
Gene Strand (Orientation) +
Protein Name RelA/SpoT family protein
DNA Sequence 
>gi|56968325:642066-644318 Brucella suis 1330 chromosome I, complete sequence
GATGATGCGCCAATATGAGCTTGTGGAGCGTGTGCAGCGATACAAGCCTGATGTGAACGAGGCGCTTCTT
AACAAGGCATATGTTTATGCCATGCAGAAACACGGCAGTCAGAAGCGGGCTTCCGGCGATCCCTATTTCT
CCCATCCGCTGGAAGTGGCGGCTATTCTCACAGATATGCATTTGGACGAGGCGACAATCGCCATCGCGCT
TCTGCACGACACGATCGAGGATACCACGGCCACCCGGCAGGAAATCGACCAGCTTTTCGGGCCGGAAATC
GGCAAGCTTGTCGAGGGGCTGACCAAGCTCAAGAAACTCGATCTCGTTTCCAAGAAGGCTGTCCAGGCGG
AAAACCTGCGTAAACTTCTGCTGGCGATTTCAGAGGACGTGCGCGTTCTTCTGGTAAAGCTTGCCGACCG
TCTCCACAATATGCGTACGCTCGGCGTGATGTGCGAAGACAAGCGCCTGCGTATTGCCGAGGAGACCATG
GATATTTATGCGCCGCTCGCTGGCCGCATGGGTATGCAGGATATGCGTGAGGAGCTGGAGGAGCTGGCTT
TCCGCTATATCAATCCCGATGCATGGCGAGCCGTCACCGACAGGCTTGCCGAGCTTCTGGAAAAGAACCG
CGGTCTTTTGCAGAAGATCGAAACGGATCTCTCTGAAATTTTCGAGAAGAACGGCATCAAGGCCAGCGTG
AAAAGCCGCCAGAAGAAGCCATGGTCGGTTTTCCGCAAGATGGAGACCAAGGGCCTTTCCTTCGAGCAGC
TTTCCGACATTTTCGGCTTCCGCGTCATGGTCGATACGGTGCAGGATTGCTATCGTGCGCTTGGCCTGAT
CCACACCACATGGTCCATGGTTCCGGGACGGTTCAAGGATTATATCTCGACGCCGAAGCAGAACGATTAT
CGCTCCATCCATACCACCATCATCGGCCCGTCGCGCCAGCGTATCGAATTGCAGATTCGCACGCGCGAAA
TGGATGAGATCGCTGAATTCGGCGTGGCGGCCCACTCCATTTACAAGGATCGTGGCAGCGCCAACAACCC
GCACAAGATTTCGACCGAGACCAACGCCTATGCATGGCTGCGCCAGACCATCGAGCAATTGTCTGAGGGC
GACAATCCTGAAGAATTTCTGGAACACACCAAGCTTGAACTGTTTCAAGATCAGGTCTTCTGCTTCACGC
CGAAAGGCAGGCTGATCGCGCTGCCGCGCGGCGCGACGCCTATTGATTTTGCCTATGCCGTTCACACCGA
TATTGGCGACAGCTGCGTGGGCGCGAAAGTCAATGGCCGCATCATGCCCTTGATGACGGAACTCAAGAAT
GGCGACGAAGTGGATATTATCCGCTCCAAGGCGCAGGTTCCGCCCGCCGCCTGGGAATCGCTGGTTGCAA
CCGGCAAGGCGCGCGCGGCCATCCGCCGCGCCACACGCTCTGCCGTGCGCAAGCAATATTCCGGCCTCGG
GATGCGAATTCTGGAGCGTGCCTTTGAGCGCGCGGGCAAACCGTTCAGCAAGGACATTTTGAAGCCTGGC
CTGCCGCGTCTGGCGCGCAAGGATGTGGAAGACGTGCTTGCAGCCGTCGGGCGTGGGGAACTGCCCTCGA
CCGATGTGGTGAAGGCCGTCTATCCCGATTATCAGGACACTCGCGTCACCACGCAGAACAATCCTGCCAA
GGCTGGCGAGAAGGGCTGGTTCAATATCCAGAACGCCGCTGGCATGATCTTCAAGGTGCCGGAAGGAGGC
GAGGGTGCTGCTGCCAAGGTTGATCCGGCGGCAACGACGCCGAAGCCCGGCAAGCGCGCACTGCCCATTC
GCGGAACCAATCCGGACCTGCCTGTGCGTTTTGCGCCGGAAGGGGCCGTGCCGGGCGACCGCATCGTGGG
CATCTTGCAGCCCGGCGCAGGCATCACGATCTATCCCATCCAGTCGCCCGCACTGACGGCCTATGACGAT
CAGCCGGAGCGCTGGATCGACGTGCGCTGGGATATCGATGACCAGATGAGCGAGCGTTTCCCCGCGCGCA
TCAGCGTATCGGCAATCAACTCGCCCGGCTCTTTGGCGAAAATTGCCCAGATTGCGGCGGCAAATGATGC
CAATATCCACAATCTCTCCATGGTGCGCACGGCGCCCGATTTTACGGAAATGATTATCGATGTAGAGGTC
TGGGACCTCAAGCATCTCAATCGCATCATCTCTCAATTGAAAGAAAGCGCGAGCGTCAGCAGCGCAAAGC
GTGTGAACGGATA
Protein Sequence 
>gi|23501539|ref|NP_697666.1| RelA/SpoT family protein [Brucella suis 1330] MMRQYELVERVQRYKPDVNEALLNKAYVYAMQKHGSQKRASGDPYFSHPLEVAAILTDMHLDEATIAIALLHDTIEDTTATRQEIDQLFGPEIGKLVEGLTKLKKLDLVSKKAVQAENLRKLLLAISEDVRVLLVKLADRLHNMRTLGVMCEDKRLRIAEETMDIYAPLAGRMGMQDMREELEELAFRYINPDAWRAVTDRLAELLEKNRGLLQKIETDLSEIFEKNGIKASVKSRQKKPWSVFRKMETKGLSFEQLSDIFGFRVMVDTVQDCYRALGLIHTTWSMVPGRFKDYISTPKQNDYRSIHTTIIGPSRQRIELQIRTREMDEIAEFGVAAHSIYKDRGSANNPHKISTETNAYAWLRQTIEQLSEGDNPEEFLEHTKLELFQDQVFCFTPKGRLIALPRGATPIDFAYAVHTDIGDSCVGAKVNGRIMPLMTELKNGDEVDIIRSKAQVPPAAWESLVATGKARAAIRRATRSAVRKQYSGLGMRILERAFERAGKPFSKDILKPGLPRLARKDVEDVLAAVGRGELPSTDVVKAVYPDYQDTRVTTQNNPAKAGEKGWFNIQNAAGMIFKVPEGGEGAAAKVDPAATTPKPGKRALPIRGTNPDLPVRFAPEGAVPGDRIVGILQPGAGITIYPIQSPALTAYDDQPERWIDVRWDIDDQMSERFPARISVSAINSPGSLAKIAQIAAANDANIHNLSMVRTAPDFTEMIIDVEVWDLKHLNRIISQLKESASVSSAKRVNG
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Regulation (Delrue et al., 2004).

FUNCTION: ppGpp synthetase (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages, HeLa (Delrue et al., 2004).
COG COG0317TK, under T: Signal transduction mechanisms; K: Transcription
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].