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htrA from Brucella suis 1330

Victor ID 1054
Gene Name htrA from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166273
NCBI Protein GI 23501498
Locus Tag BR0611
Protein Accession NP_697625.1
Other Database IDs UniProtKB-ID: DEGP_BRUSU
UniRef100: UniRef100_Q2YMX6
UniRef90: UniRef90_Q2YMX6
UniRef50: UniRef50_Q2YMX6
UniParc: UPI0000129172
EMBL: AE014291
EMBL-CDS: AAN29540.1
RefSeq_NT: NC_004310.3
GenomeReviews: AE014291_GR
KEGG: bms:BR0611
TIGR: BR0611
HOGENOM: HBG585708
OMA: ASAMREA
ProtClustDB: CLSK864818
BioCyc: BSUI204722:BR_0611-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 600019
Gene Ending Position 601560
Gene Strand (Orientation) +
Protein Name serine protease
DNA Sequence 
>gi|56968325:600019-601560 Brucella suis 1330 chromosome I, complete sequence
GATGTCCAGAGCCAGGATTTCCAACTATCGCAAAGGCGTTGCCGCCGTCGCGCTTTCCGCAGCGCTTGCC
GGCGCATTCGTCGTAACCGGCCCGCTTGGTGCGCTGAACGAAGCCCGCGCCGAAGCGGTGCATGTGACGC
CGCCGCCGCAGGCTGGCTTTGCCGATCTGGTGGAAAAGGTTCGCCCTGCGGTCGTCAGCGTCCGCGTCAA
GAAGGACGTGCAGGAGACTTCCAACCGTGGTCCGCAGTTCTTCGGCCCTCCCGGCTTCGACCAGTTGCCG
GACGGTCATCCGCTTAAGCGATTTTTCCGTGATTTTGGTATGGAGCCGCGTGGCGATTCACGCTCCGATA
ACCGTCGCGGCAAGGCCAACAAGCCGCGCCCGGGCCATGAACGCCCTGTTGCACAAGGATCGGGCTTCGT
CATTTCCGAAGATGGCTATGTCGTTACCAACAACCATGTCGTTTCCGATGGCGATGCCTATACCGTCGTG
CTGGACGACGGCACCGAACTTGATGCCAAGCTGATTGGTGCTGATCCGCGCACGGACCTGGCCGTGTTGA
AAATCAACGCTCCGAAGCGCAAGTTCGTCTATGTCGCCTTTGGCGACGATAATAAGGTGCGCGTCGGTGA
TTGGGTTGTCGCAGTTGGCAATCCGTTCGGCCTTGGTGGCACGGTGACTTCCGGTATCGTTTCGGCCCGT
GGCCGAGACATCGGCGCAGGCCCCTATGACGATTTCATCCAGATTGATGCCGCCGTGAACAAGGGCAATT
CCGGTGGTCCGGCTTTCGACCTTTCCGGCGAAGTCATCGGCATCAACACCGCCATCTTCTCGCCATCTGG
CGGCAGCGTGGGCATTGCTTTTGCAATTCCGTCCTCCACCGCCAAGCAGGTCGTGGACCAGCTCATCAAG
AAGGGTTCCGTCGAGCGCGGCTGGATCGGCGTCCAGATACAGCCTGTGACCAAGGATATCGCCGCTTCGC
TCGGTCTTGCCGAGGAAAAGGGTGCGATCGTGGCCTCGCCGCAGGATGATGGCCCGGCTGCCAAGGCTGG
CATCAAGGCGGGCGATGTGATTACGGCTGTCAATGGCGAAACGGTTCAGGACCCGCGTGACCTGGCGCGC
AAGGTTGCCAATATCGCTCCTGGTGAAAAGGCGGCCCTGACCGTCTGGCGCAAGAACAAGGCCGAGGAAA
TCAACGTCACGATTGCTGCCATGCCCAATGACAAGGGGAAGAGCGGCAGCCAGTCCAACGACAATGACGG
CGGACAGGGTGAAACGCTCGACTCCTACGGCTTGACCGTCGTTCCGTCTGAAGACGGTAAGGGCGTGGTC
GTTACCGATGTGGACCCGGACAGCGATGCGGCTGACCGTGGCATCCGCTCCGGCGATGTGATCGTGAGCG
TCAACAACCAGACGGTAAAGACCGCTGGCGATATCAACAAGGCCATCACGGCAGCCGAAAAGTCAGGCCG
TAAGGCGGTGCTGCTGCAATTGCAGAGCAATGATCAGAGCCGCTTCGTGGCGCTGCCGATCAATCAGGAA
TG
Protein Sequence 
>gi|23501498|ref|NP_697625.1| serine protease [Brucella suis 1330] MSRARISNYRKGVAAVALSAALAGAFVVTGPLGALNEARAEAVHVTPPPQAGFADLVEKVRPAVVSVRVKKDVQETSNRGPQFFGPPGFDQLPDGHPLKRFFRDFGMEPRGDSRSDNRRGKANKPRPGHERPVAQGSGFVISEDGYVVTNNHVVSDGDAYTVVLDDGTELDAKLIGADPRTDLAVLKINAPKRKFVYVAFGDDNKVRVGDWVVAVGNPFGLGGTVTSGIVSARGRDIGAGPYDDFIQIDAAVNKGNSGGPAFDLSGEVIGINTAIFSPSGGSVGIAFAIPSSTAKQVVDQLIKKGSVERGWIGVQIQPVTKDIAASLGLAEEKGAIVASPQDDGPAAKAGIKAGDVITAVNGETVQDPRDLARKVANIAPGEKAALTVWRKNKAEEINVTIAAMPNDKGKSGSQSNDNDGGQGETLDSYGLTVVPSEDGKGVVVTDVDPDSDAADRGIRSGDVIVSVNNQTVKTAGDINKAITAAEKSGRKAVLLQLQSNDQSRFVALPINQE
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Stress proteins/Chaperones (Kohler et al., 2002).

FUNCTION: Protease (Kohler et al., 2002).

MUTATION: Attenuated in "Goat", Macrophages, but not in Mice (Kohler et al., 2002).
COG COG0265O, under O: Posttranslational modification, protein turnover, chaperones
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].