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mgtC from Mycobacterium tuberculosis H37Rv

Victor ID 105
Gene Name mgtC from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885439
NCBI Protein GI 15608948
Locus Tag Rv1811
Protein Accession NP_216327.1
Other Database IDs UniProtKB-ID: O07221_MYCTU
UniRef100: UniRef100_A1KJM2
UniRef90: UniRef90_A1KJM2
UniRef50: UniRef50_A1KJM2
UniParc: UPI00000D1069
EMBL: AE000516
EMBL: BX842577
EMBL-CDS: AAK46132.1
EMBL-CDS: CAB09501.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 9.B.20.1.2
EnsemblGenome: EBMYCG00000000871.
EnsemblGenome_TRS: EBMYCT00000000871
EnsemblGenome_PRO: EBMYCP00000000871
EnsemblGenome: EBMYCG00000070136.
EnsemblGenome_TRS: EBMYCT00000070141
EnsemblGenome_PRO: EBMYCP00000068200
GenomeReviews: AE00
Taxonomy ID 83332
Gene Starting Position 2053442
Gene Ending Position 2054146
Gene Strand (Orientation) +
Protein Name POSSIBLE Mg2+ TRANSPORT P-TYPE ATPASE C MGTC
DNA Sequence 
>gi|57116681:2053442-2054146 Mycobacterium tuberculosis H37Rv, complete genome
CATGCAAACGCTGACTGTCGCCGATTTCGCTCTCCGGCTGGCCGTCGGAGTGGGTTGCGGGGCCATTATC
GGGCTCGAGCGCCAGTGGCGGGCGCGGATGGCTGGGTTGCGCACCAACGCTCTGGTGGCGACCGGTGCTA
CCTTGTTCGTGCTGTACGCGGTCGCCACCGAGGACAGCAGCCCCACCCGAGTGGCGTCCTACGTGGTTTC
TGGAATTGGATTCCTGGGCGGCGGGGTCATCCTGCGGGAGGGGTTCAACGTCCGCGGTCTGAACACGGCT
GCCACGCTTTGGTGCTCGGCCGCGGTCGGAGTGCTGGCCGCCTCCGGGCATCTGGTGTTCACCCTGATTG
GCACCGGAACCATCGTCGCTGTCCATCTCCTGGGGCGCCCACTTGGCCGGCTGGTCGACCGCGACAACGC
CGTCGAAGACGAAGGGCTGCAGCCCTACCAGGTACGGGTGATTTGTCGGCCCAAAGCAGAGACCTATGTA
CGTGCCCATATCGTGCAGCGCACCAGCAGCAACGACATCACGCTGCGGGGTATACGCACGGGGCCGGCCG
GAGACGACAACATCACGTTGACGGCCCACCTATTGATGGTTGGCCATACCCCGGCCAAGCTAGAGCGGTT
GGTGGCGGAACTGTCGCTGCAGCCGGGCGTTTACGCTGTGCACTGGTATGCCGGTGAGCACGCGCAGGCC
GAATG
Protein Sequence 
>gi|15608948|ref|NP_216327.1| Mg2+ transport P-type ATPase MgtC [Mycobacterium tuberculosis H37Rv] MQTLTVADFALRLAVGVGCGAIIGLERQWRARMAGLRTNALVATGATLFVLYAVATEDSSPTRVASYVVSGIGFLGGGVILREGFNVRGLNTAATLWCSAAVGVLAASGHLVFTLIGTGTIVAVHLLGRPLGRLVDRDNAVEDEGLQPYQVRVICRPKAETYVRAHIVQRTSSNDITLRGIRTGPAGDDNITLTAHLLMVGHTPAKLERLVAELSLQPGVYAVHWYAGEHAQAE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mgtC mutant is attenuated in human macrophages and mice (Buchmeier et al., 2000).
COG COG1285S, under S: Function unknown
References
Buchmeier et al., 2000: Buchmeier N, Blanc-Potard A, Ehrt S, Piddington D, Riley L, Groisman EA. A parallel intraphagosomal survival strategy shared by mycobacterium tuberculosis and Salmonella enterica. Molecular microbiology. 2000; 35(6); 1375-1382. [PubMed: 10760138].