Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

gmd from Brucella suis 1330

Victor ID 1048
Gene Name gmd from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166184
NCBI Protein GI 23501417
Locus Tag BR0522
Protein Accession NP_697544.1
Other Database IDs UniProtKB-ID: Q8G219_BRUSU
UniRef100: UniRef100_D0B1X8
UniRef90: UniRef90_D0B1X8
UniRef50: UniRef50_O60547
UniParc: UPI000005806B
EMBL: AE014291
EMBL-CDS: AAN29459.1
RefSeq_NT: NC_004310.3
HSSP: P32054
GenomeReviews: AE014291_GR
KEGG: bms:BR0522
TIGR: BR0522
HOGENOM: HBG755066
OMA: TQRVDHI
ProtClustDB: CLSK864399
BioCyc: BSUI204722:BR_0522-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 520906
Gene Ending Position 521994
Gene Strand (Orientation) -
Protein Name GDP-mannose 4,6-dehydratase
DNA Sequence 
>gi|56968325:520906-521994 Brucella suis 1330 chromosome I, complete sequence
ATCATTCCTTAGGGGCGAAAAATTGGTGACCATGTTCGCGCAGCAAATTCTCACGAGCCGCCGCCGCTAA
GTCTTCTGCTATCATCTCAGATACAAGCGTCTCAAAAGAGATTTTCGGCTTCCAGCCCAGTTTTTGATGC
GCCTTGGTCGCATCTCCCAGAAGAGTTTCCACCTCGGCTGGTCGAAAGTATCTAGGATCGACCTCGACAA
TACATGCACCGGTCTTGGCATCATAACCCTTCTCGGCTTCACCGCTACCTTCCCATCGCATCTCAATGCC
TATGTCTTTAGCAGCGAGCGTGACAAATTCTCGAACTGAATATTGTTTACCAGTTGCTATTACAAAATCT
TCTGGTTGATCCTGTTGAAGCATTAACCACTGCATCTCGACGTAGTCCCGAGCATGCCCCCAGTCGCGTA
ATGAGTCCAAATTCCCTAAGTATAAGCGATTCTGATTACCGATCTTAATTCTAGCTAAAGCGCGAGTAAT
TTTTCTCGTGACAAAAGTCTCTCCTCTAAGTGGAGATTCATGGTTAAAAAGTATGCCATTACAAGCATAT
ATACCATACGCCTCTCGGTAGTTTACCGTAATCCAATAGGCATAAAGCTTCGCTGCGGCATAGGGCGACC
GAGGGTAAAAAGGCGTCGTTTCTTTTTGCGGGATTTCTTGAACCAGACCATAAAGCTCAGAGGTGGATGC
TTGGTAGTACCGGGTCTGCTTCTCCATTCCAAGAATTCGGATCGCCTCTAGCAGACGAAGGGCACCTAGT
GCGTCTGAGTTCGCAGTATACTCCGGCTCCTCAAATGAAACAGCAACATGGCTTTGTGCGCCAAGGTTAT
AAACTTCATCCGGCCGAACGAGCTGCATGATTCGAACCAAGCTTGACGTATCTGTTAGATCGCCATGATG
AAGTGTTAGATCGACACCCTGCTCGTGCGGATCATGGTACAGATGATCGATACGTGCTGTGTTAAATTGC
GAGGTGCGACGCTTAATCCCGTGTACTGCATAACCTTTTTGTAGAAGCAATTCCGCAAGGTAGGCGCCGT
CTTGGCCGGTGATACCTGTGATAAGTGCGACTTTCTTCA
Protein Sequence 
>gi|23501417|ref|NP_697544.1| GDP-mannose 4,6-dehydratase [Brucella suis 1330] MKKVALITGITGQDGAYLAELLLQKGYAVHGIKRRTSQFNTARIDHLYHDPHEQGVDLTLHHGDLTDTSSLVRIMQLVRPDEVYNLGAQSHVAVSFEEPEYTANSDALGALRLLEAIRILGMEKQTRYYQASTSELYGLVQEIPQKETTPFYPRSPYAAAKLYAYWITVNYREAYGIYACNGILFNHESPLRGETFVTRKITRALARIKIGNQNRLYLGNLDSLRDWGHARDYVEMQWLMLQQDQPEDFVIATGKQYSVREFVTLAAKDIGIEMRWEGSGEAEKGYDAKTGACIVEVDPRYFRPAEVETLLGDATKAHQKLGWKPKISFETLVSEMIAEDLAAAARENLLREHGHQFFAPKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: gmd may be involved in perosamine synthesis. It has been shown to be in LPS synthesis since its B. melitensis mutation induces rough phenotype (Moriyón et al., 2004).
COG COG1089M, under M: Cell wall/membrane/envelope biogenesis
References
Moriyón et al., 2004: Moriyón I, Grilló MJ, Monreal D, González D, Marín C, López-Goñi I, Mainar-Jaime RC, Moreno E, Blasco JM. Rough vaccines in animal brucellosis: structural and genetic basis and present status. Veterinary research. 2004; 35(1); 1-38. [PubMed: 15099501].