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purF from Brucella suis 1330

Victor ID 1040
Gene Name purF from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1166107
NCBI Protein GI 23501347
Locus Tag BR0446
Protein Accession NP_697474.1
Other Database IDs UniProtKB-ID: Q8G282_BRUSU
UniRef100: UniRef100_D0B1Q7
UniRef90: UniRef90_D0B1Q7
UniRef50: UniRef50_B9JUS7
UniParc: UPI00000DD2D1
EMBL: AE014291
EMBL-CDS: AAN29389.1
RefSeq_NT: NC_004310.3
HSSP: P00497
MEROPS: C44.001
GenomeReviews: AE014291_GR
KEGG: bms:BR0446
TIGR: BR0446
HOGENOM: HBG392416
OMA: GIPFELG
ProtClustDB: PRK09123
BioCyc: BSUI204722:BR_0446-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 446054
Gene Ending Position 447511
Gene Strand (Orientation) -
Protein Name amidophosphoribosyltransferase
DNA Sequence 
>gi|56968325:446054-447511 Brucella suis 1330 chromosome I, complete sequence
ATCAGCCGTTGCTGGCGAGCAGCGACAAGGTGTGGACGTTGCTTTCGCCTTCCTGATCCAGAAGGCGGGT
CGGATACTCGCCCGTGAAATAGTGATCGGTGAAGGTCGGCGCCTTTGGATCACGCGGCTTTCCGCCAACG
GCCTTGTAGAGCCCGTCGATGGAAAGGAAGGCCAGCGAATCGGCGCCGATGTAGCGGCACATGGATTCGA
GGCTTTCGTGCTGGTTGGCCAGCAGCTTATCGGCATGGGGGGTGTCGATACCGTAAAAATCCGGGTGGAA
GATCATCGGGCTTGCCACGCGCATATGGACTTCGGTTGCGCCTGCGTCGCGGATCATCTGAACGATCTTG
ACCGAGGTGGTGCCGCGCACGATGGAATCATCCACCAGAACGACCCGCTTGCCTTCAATCATAGCGCGAT
TGGCTGAATGTTTCAGCTTCACGCCAAGCGCGCGGATCTGCTGTGTAGGCTCAATGAAGGTGCGGCCCAC
ATAATGGTTGCGGATGATGCCATATTCAAACGGAATACCGCTTGCCTGCGCAAAGCCCAGCGCTGCCGGC
GTACCGCCATCCGGTACGGGCACGACCACATCGGCATCCACGCCCGCCTCGGCGGCAAGGTTCATGCCCA
TGTTCTTGCGCGCCACATAGACGCTGCGGCCACCCACTACCGAATCCGGCCGTGCGAAATAAACATATTC
AAAAAGGCACAGCCGCTCCGGCTGCGGATTTTCCGGCTTGATGGATCGGGTGGTGATGGAGCCATCCTTC
TGGATTTCGCAGACTACCACTTCGCCATTCTCGACGTCGCGAATATATTTCGCGCCGATAATATCGAGAG
CGCAGGTTTCCGAGCAGAAGATCGGCTTGCCGTCCAGCTCGCCCATGACGAGCGGGCGAATGCCGATGGG
ATCGCGCGCGGCGATCAGCTTGGTGCGGGTAAGCGCCAGCATGGCATAGCCGCCTTCAACCTGGCGGATC
GCTTCCACGAAACGGTCGGTTGAGGAGGAGTGCCGCGAACGGGCAATCATGTGCAGCACGACTTCCGTAT
CCGACGTTGCCTGGAAGATCGCGCCGGAAGCAATCAACTGTTTGCGCAGCGTAATGCCATTGGTGAAATT
GCCGTTATGGGCAATGGCGATGCCGCCGACTTCCAGTTCCGCAAACAGCGGCTGTACATTGCGCAGGATC
GTCTCGCCGGTTGTGGAATAACGCACATGGCCGATGGCGCGGTTGCCCGGCAGGCGGTTCAGTGTTGCCG
CATCGGTGAAATGGTCGCCGACGAGGCCCATATGGCGTTCGGAATGGAAACGGCGATTATGATAGGAAAC
AATGCCGGCGGCTTCCTGACCGCGATGCTGGAGCGCATGCAGGCCGAGCGCGGTCAGCGCAGCCGCATCC
TCATGGCCCAGAATGCCGAATACACCACATTCTTCATGCAGGGTGTCATCATCCAGCA
Protein Sequence 
>gi|23501347|ref|NP_697474.1| amidophosphoribosyltransferase [Brucella suis 1330] MLDDDTLHEECGVFGILGHEDAAALTALGLHALQHRGQEAAGIVSYHNRRFHSERHMGLVGDHFTDAATLNRLPGNRAIGHVRYSTTGETILRNVQPLFAELEVGGIAIAHNGNFTNGITLRKQLIASGAIFQATSDTEVVLHMIARSRHSSSTDRFVEAIRQVEGGYAMLALTRTKLIAARDPIGIRPLVMGELDGKPIFCSETCALDIIGAKYIRDVENGEVVVCEIQKDGSITTRSIKPENPQPERLCLFEYVYFARPDSVVGGRSVYVARKNMGMNLAAEAGVDADVVVPVPDGGTPAALGFAQASGIPFEYGIIRNHYVGRTFIEPTQQIRALGVKLKHSANRAMIEGKRVVLVDDSIVRGTTSVKIVQMIRDAGATEVHMRVASPMIFHPDFYGIDTPHADKLLANQHESLESMCRYIGADSLAFLSIDGLYKAVGGKPRDPKAPTFTDHYFTGEYPTRLLDQEGESNVHTLSLLASNG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A B. suis purF mutation experiment suggests that the purine biosynthesis pathway contributes to intracellular growth (Kim et al., 2003).
COG COG0034F, under F: Nucleotide transport and metabolism
References
Kim et al., 2003: Kim S, Watarai M, Kondo Y, Erdenebaatar J, Makino S, Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infection and immunity. 2003; 71(6); 3020-3027. [PubMed: 12761078].