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vsrB from Brucella suis 1330

Victor ID 1035
Gene Name vsrB from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1165977
NCBI Protein GI 23501223
Locus Tag BR0316
Protein Accession NP_697350.1
Other Database IDs UniProtKB-ID: Q8G2K3_BRUSU
UniRef100: UniRef100_Q8G2K3
UniRef90: UniRef90_A9M899
UniRef50: UniRef50_A9M899
UniParc: UPI00000DD26D
EMBL: AE014291
EMBL-CDS: AAN29265.1
RefSeq_NT: NC_004310.3
GenomeReviews: AE014291_GR
KEGG: bms:BR0316
NMPDR: fig|204722.1.peg.307
TIGR: BR0316
HOGENOM: HBG564495
OMA: KEFHRLE
ProtClustDB: CLSK864365
BioCyc: BSUI204722:BR_0316-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 327132
Gene Ending Position 330656
Gene Strand (Orientation) -
Protein Name sensor histidine kinase/response regulator
DNA Sequence 
>gi|56968325:327132-330656 Brucella suis 1330 chromosome I, complete sequence
CTTATCGTGTACTGCCTTGCGTCGATGCCCCGTCCTGGCGTGCGTGATGAAAAAGCGAGAGCATCGAGCG
CAGCGCCGCTGGCCGCAAGGGCTTGTGCAGCACGGTGACGTTCTCATCCTCGGCGCGCTGGCGCACCTCC
TTGGAGCGGTCGGCAGTTAGCAGGATGGCCGGTATTTCGGTCTTGAAGCTTTCGCGCGCAAAGCCGATCA
TGTCGAGGCCGTTTTCGTGGATCAGATGATAATCGGCAATGATGACGGCAGGCGCGGCCGTGCCGGTTGC
GCAGAAGTTTTTCAACTCCGCGCCGCTGCGAAGCGTGGTCACGTTGCAGCCCCAGCCGCTCAGCAGCGTT
TCCATGCCGCATAGAATATTGACGTCATTGTCGATGCAAAGGACGCCAAGCCCGTCAAGCTCGGAAGCGC
GCTGAGGCCCGCGACGGTTTTTAACCTCTTCGGCTGGCGGCGCCTCGCCTGAAACCGGAATGCGCAGCGA
AAACACCGTACCTTTGCCGGGTGTTGAGGCAAGCGACAGCGGCAGCGAAAGCACCCGCGCGATGCGGTCC
ACGATGGAAAGGCCAAGCCCCAGCCCTTCGGCTTCCCGCATGCCTTCGTTGAGCCGCGTGAACTCCCAGA
AGACGAGCTTCAGTTTTTGTGGCGCAATGCCGATGCCGGTGTCGAGCACCTGCAGGTCGACGAAATTTCC
GCGCCGCCGCACGCCCAGCAATATGCCGCCCTTGCGACTATATTTGATCGAGTTGGAAACGAGGTTCTGG
ATCAGGCGGCGCAGCATGTTGCGGTCGGTCTTGACCACGATGCTGGATGGCACCACACGCAGCTTGAGCC
CTTTTTTCACCGCCAGCGGTGTGAAATCGGTAGCGATCTGGCTCAACAGCTTGTCGAGCCGGAAGACGGA
AGTTTCCGGTTTCAGCGAGCCGGTATCGAGCCGGGAAATATCCAGCACCATGCCGAGAATGGCTTCCACC
GCTTCCAGCGAGGAATCGATATTGCGGGCAAATTCGCTGGTTTCCGAACGCCCCAGTTTTTCAGCAAGCG
CCGTGGAATAAAGGCGCGCAGCGTTGAGCGGTTGCAGAATGTCATGGCCCGCAGCCGCCAGAAAGCGCGT
CTTGCCCAGATTGGCTTCTTCTGCGGCGGCTTGCGCGCGCGCAAGCTCATCGTTCACATGCATCAGTTCC
GCTGTACGGTCGATAACGCGCTGCTCCAGCATTTCCGATGCTTTCTGGCGCATCAGGTCGGCTTCCACCG
CGGCCGTGATGTCGGTAAAGGTGGTGACAAGGCCCCCATCCGGCATCGGATTGGAATTGATTTCGAGAAT
CTTGCCGGTCGATTTCATGGTCATGCGCCATGGGCGGCGCACGGTGCCGAGCGAGCGGATTGCGCTATTA
CGGGCATTCAGGGCGATGTCGCCGCGCTGGCTTAGATGTTCCACGATTTCAGAGATCGGAATGCCTACCT
GCATCACCTCGTCCGGCAGGTCGAAGAGCTTGCGGAACTGCCGGTTCCAGCAGGTCAGGCGCAGATCCTT
GTCAAGAACGGTGATGCCCTGATCCATCTGGTCCAGCGCGATCTGCAACAGGTCGCGGTTCTGTTGCAGG
GCAGCAGAAGCATCGTCCAGCAATTGGCGTGCATCGCGCGGCGAGGCATCGTTTCTTTGCAGAAGAAGCG
AAAGAACAAGGCGGGCTGAGGATGAGCCGACGGCTGTCCCAAGCAATTGTTCGGCATAGCGGATCAGGGG
CGTGTCCACGGTCATGCCGGGGTCGAGGCGGCGCTGTTCGCGGCCCTCGAAGCGCAGGAAGGCGCGCTCC
ACGCGCTCAGCACCCAGATAGCGCGCCATGGTGGCCTTGAGTTCGGCGACCGTGACCGTGGTTCGGAAAC
GTTTCAGCGTCGGCGCGCCGATGAAAGTGCGCGGCAGGAAAATGCTGGCCTGGATGCGTTCCAGCGGTGT
GGATGCGCGCGAGAGCGAGCCCAGAATATAGAACAGGGTGTTGGCGGCAATGCTCCATGCCACGCCGTTG
GTAAGCGGCAGGGCATTGGTGCCGAACAGCGCTTCGGGGCGCAGTGCCGTGAAGCCGAGGAAACCATCCC
GCAGGATCGCGGCATTTTCCGGTGCGACGGTTGGCAGAAGCAGCGTGTAGCACCAGACGATGAAGCCCGC
CGAAAGGCCGAGCATCGCGCCGCGCCCGTTTGCATTGCGCCAGAACAGCCCGCCAATGAGCGCTGGCGCA
AATTGCGCGACGGCGGCAAAGGATACGAAGCCGATGGAGGCCAGATGGATATTGTTCGATGTGAGGCGAT
AATAGCTGAAGGCCAGCGCCAGAATGACGATGATGGTGATGCGGCGCGTGTTGAGAATGATCTTGGTCAG
GTCGCGCTGTTCGGCAAGGTGGCGCTTGGCAAAGCTGCTGATGATAAGCGGCAGCACCAGATGGTTGGAG
ATCATGATAGACAGTGCCACGCAGGCGACGATCACCATGGCCGTTGCCGCTGAAAGGCCGCCGAGGAAGG
CGATGAGCGCCAGCCAGTGTGCTCCCGCGCTGAGCGGCAGGGCAAGCACGTAAAGGTCGCCATTGACGCT
GTTGCCGAGCGTCATCACGCCGATGAGCGCGATGGGGAAGACGAAAATATTGATGAGGATGAGATAGAGC
GGAAACAGCCATGAGGCCGTGCGCAATTCCTTCTCGCTGCGGCTTTCCACGACCGTCACATGGAACTGGC
GCGGCAGCATGATGACGGCGGCGGCGCTGAGTGCTGTCTGCACGAGCCATGTGCCGATTGAGGTCTCGTA
ATGGAAGGCTTCGAGTGCTTCCGGCGATTGGGATATCTGCCGGATGAGCTGCGATGGCGCGCCGAACAGG
AAGAAGGCGCAGGCAAGGCCGACGGTCAGGAAGGCGCACAGCTTGATGACCGATTCCAGCGCCACGGCAA
GAATGAGGCCATTCTGGTGTTCGGTCGCATCCGTATGGCGCGTGCCGAAAAGGATTGCGAAGGTGGCGAG
CACGGCTGCGACCGGCAGGGAAATATCGCCGAAGACGAAGACGGCTGGATCGACGGCTGCTCCGTAATAA
TCCATCACGAGGCCGACACCGCCCGAAACTGCTTTCAGTTGCAGCGCGATATAGGGAATGGAGCCGACGG
CGGCAATGCAGGTGGCAAGCGAGGCGACGCCGAAGCTCTTGCCATAGCGCGCCGCCAGAAAATCGGCGAT
GGAGGTGATGTGCTCGGATTTGGCCAGCCGCACGATATGGCGCAGCAGCCGGTTGCCAAGCGTAAAGACG
AGAATGGGGCCGATATAGATGCCAAGAAACTCAAGCCCGCGTTGCGCGGAAAGCCCGACCGAGCCGAAAA
AGGTCCAGGAGGTGCAATAGACGGCGAGGCTCAGCGCATAGATATAGGGGCGCGGCGTGCTGCTCCAGCG
CGCGGTGCGCCGGTCCCCGATGCTTGCAACCGCAAAGAGAAGCAGCAGGTATAAAAAGGCGAAGCCAATG
ATCCCCCAGCCCTGCATAGCCGGCA
Protein Sequence 
>gi|23501223|ref|NP_697350.1| sensor histidine kinase/response regulator [Brucella suis 1330] MPAMQGWGIIGFAFLYLLLLFAVASIGDRRTARWSSTPRPYIYALSLAVYCTSWTFFGSVGLSAQRGLEFLGIYIGPILVFTLGNRLLRHIVRLAKSEHITSIADFLAARYGKSFGVASLATCIAAVGSIPYIALQLKAVSGGVGLVMDYYGAAVDPAVFVFGDISLPVAAVLATFAILFGTRHTDATEHQNGLILAVALESVIKLCAFLTVGLACAFFLFGAPSQLIRQISQSPEALEAFHYETSIGTWLVQTALSAAAVIMLPRQFHVTVVESRSEKELRTASWLFPLYLILINIFVFPIALIGVMTLGNSVNGDLYVLALPLSAGAHWLALIAFLGGLSAATAMVIVACVALSIMISNHLVLPLIISSFAKRHLAEQRDLTKIILNTRRITIIVILALAFSYYRLTSNNIHLASIGFVSFAAVAQFAPALIGGLFWRNANGRGAMLGLSAGFIVWCYTLLLPTVAPENAAILRDGFLGFTALRPEALFGTNALPLTNGVAWSIAANTLFYILGSLSRASTPLERIQASIFLPRTFIGAPTLKRFRTTVTVAELKATMARYLGAERVERAFLRFEGREQRRLDPGMTVDTPLIRYAEQLLGTAVGSSSARLVLSLLLQRNDASPRDARQLLDDASAALQQNRDLLQIALDQMDQGITVLDKDLRLTCWNRQFRKLFDLPDEVMQVGIPISEIVEHLSQRGDIALNARNSAIRSLGTVRRPWRMTMKSTGKILEINSNPMPDGGLVTTFTDITAAVEADLMRQKASEMLEQRVIDRTAELMHVNDELARAQAAAEEANLGKTRFLAAAGHDILQPLNAARLYSTALAEKLGRSETSEFARNIDSSLEAVEAILGMVLDISRLDTGSLKPETSVFRLDKLLSQIATDFTPLAVKKGLKLRVVPSSIVVKTDRNMLRRLIQNLVSNSIKYSRKGGILLGVRRRGNFVDLQVLDTGIGIAPQKLKLVFWEFTRLNEGMREAEGLGLGLSIVDRIARVLSLPLSLASTPGKGTVFSLRIPVSGEAPPAEEVKNRRGPQRASELDGLGVLCIDNDVNILCGMETLLSGWGCNVTTLRSGAELKNFCATGTAAPAVIIADYHLIHENGLDMIGFARESFKTEIPAILLTADRSKEVRQRAEDENVTVLHKPLRPAALRSMLSLFHHARQDGASTQGSTR
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Regulation (Delrue et al., 2004).

FUNCTION: Histidine kinase (Delrue et al., 2004).

MUTATION: Attenuated in Mice, Macrophages, HeLa (Delrue et al., 2004).
COG COG0591ER, under E: Amino acid transport and metabolism; R: General function prediction only
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].