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metH from Brucella suis 1330

Victor ID 1030
Gene Name metH from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1165845
NCBI Protein GI 23501099
Locus Tag BR0188
Protein Accession NP_697226.1
Other Database IDs UniProtKB-ID: Q8G2X1_BRUSU
UniRef100: UniRef100_Q8G2X1
UniRef90: UniRef90_B0CJ47
UniRef50: UniRef50_B3QGP3
UniParc: UPI00000DD20C
EMBL: AE014291
EMBL-CDS: AAN29141.1
RefSeq_NT: NC_004310.3
HSSP: P13009
GenomeReviews: AE014291_GR
KEGG: bms:BR0188
NMPDR: fig|204722.1.peg.183
TIGR: BR0188
HOGENOM: HBG289648
OMA: YVTDASR
ProtClustDB: PRK09490
BioCyc: BSUI204722:BR_0188-MONOMER
Taxonomy ID 204722
Chromosome No I
Gene Starting Position 197175
Gene Ending Position 200960
Gene Strand (Orientation) +
Protein Name B12-dependent methionine synthase
DNA Sequence 
>gi|56968325:197175-200960 Brucella suis 1330 chromosome I, complete sequence
TATGGCGTCTTCCCTTGACGATCTTTTTGGTGCAACGGCGGCAAAGCCGGACGGTTCGGAAGTGCTGGCG
GCACTGACCCAGGCGGCGCGCGAGCGCATCCTGATCCTCGACGGCGCCATGGGTACGCAGATTCAGGGCC
TGGGTTTCCATGAAGAGCATTTTCGCGGCGATCGTTTCGCCACCTGTGACTGCCAGCTTCAGGGCAATAA
CGATCTTCTGACCTTGACCCAGCCGAAAGCCATTGAGGAAATCCACTATGCCTATGCCATGGCGGGCGCG
GATATTCTCGAAACCAATACTTTCTCCTCCACTTCCATCGCGCAGGCCGATTATGGCATGGAGGCGATGG
TCTATGATCTCAATCGCGATGGCGCACGCCTTGCCCGCCGCGCAGCCTTGCGCGCCGAGCAGAAGGACGG
CCGCCGCCGCTTTGTCGCGGGCGCACTGGGGCCGACGAACCGCACCGCCTCGCTGTCCCCGGATGTGAAC
AATCCGGGCTTTCGCGCCGTCACTTTCGATGATCTGCGCATTGCCTATTCCGAACAGATTCGCGGCCTGA
TCGATGGCGGTTCCGACATCATCCTGATCGAAACCATTTTCGATACGCTGAACGCCAAGGCGGCTGTGTT
CGCGACCGAGGAAGTCTTTGCCGAAAAGGGTGTTCGCCTTCCGGTCATGATCTCCGGTACGATCACCGAT
CTTTCCGGGCGCACGCTTTCCGGCCAGACGCCGACGGCCTTCTGGTATTCACTGCGCCATGCAAGACCGT
TCACCATCGGACTGAATTGCGCCCTTGGCGCCAATGCCATGCGTGCGCATCTGAATGAATTGTCGGGCAT
TGCCGACACCTTTATCTGCGCCTATCCCAATGCCGGCCTTCCGAACGAATTCGGCCAGTATGATGAAACG
CCGGAAGCCATGGCCGCGCAGATCGAGGGCTTTGCTCGCGACGGGCTGGTCAATGTTGTTGGCGGCTGCT
GCGGCTCCACGCCTGACCATATTCGCGCCATCGCGCAAGCCGTCGCGAAATATGAGCCACGCAAGCCCGC
AAAAGTGCCGCCGCTGATGCGCCTTTCCGGCCTTGAGCCCTTTACGCTCACCAAGGATATTCCTTTCGTC
AATATCGGCGAGCGCACCAATGTCACCGGCTCGGCCCGCTTCCGCAAGCTCGTCAAGGCCGGCGATTTCG
CGGCTGCGCTCGATGTTGCGCGCGATCAGGTGGCCAACGGCGCCCAGATCATCGATATCAACATGGATGA
AGGCCTGATCGATTCCGAAAAGGCCATGGTCGAGTTTTTGAACCTTATTGCCGCCGAGCCGGATATCGCC
CGCGTGCCGATCATGCTCGACAGCTCCAAATGGGAAGTGATCGAGGCTGGCCTGAAATGCGTTCAGGGCA
AGGCAGTCGTCAATTCCATCTCGCTGAAAGAGGGTGAGGAAGCCTTTCTTCACCATGCGCGGCTGGTGCG
TGCCTATGGTGCCGCTGTGGTCATCATGGCGTTCGATGAAACCGGACAGGCGGATACGCAGGCCCGCAAG
ATCGAAATCTGCACCCGCGCCTATAAAATCCTGACCGAACAGGTGGGTTTCCCGCCGGAAGACATCATTT
TCGATCCGAATATTTTTGCGGTCGCGACCGGCATCGAGGAACACAATAATTACGGCGTCGATTTCATCGA
GGCCACGCGTGAAATCGTCCGCACACTGCCGCATGTCCATATTTCCGGCGGCGTTTCCAACCTCTCGTTC
TCCTTCCGCGGCAATGAGCCGGTGCGTGAGGCGATGCATGCCGTTTTCCTCTACCACGCCATTCAGGCGG
GCATGGATATGGGCATCGTCAATGCGGGCCAGCTTGCGGTCTATGACACGATCGACGCTGAACTGCGTGA
GGCTTGCGAGGATGTGGTGCTGAACCGCCCCACAAAAACGGGCGAAAGCGCAACCGAACGGCTTCTGGAA
ATTGCCGAACGGTTCCGTGATTCCGGCTCCAGGGAAGCGCGGACGCAGGATTTGAGCTGGCGCGAATGGC
CGGTCGAAAAGCGGCTTGAACATGCGCTGGTCAACGGCATCACCGAATATATCGAGGCCGATACGGAAGA
GGCGCGCCTTGCTGCCGAGCGCCCGTTGCATGTGATCGAAGGGCCGCTGATGGCAGGCATGAATGTGGTC
GGCGACCTGTTCGGTTCCGGCAAGATGTTTCTGCCGCAGGTGGTGAAATCTGCCCGCGTGATGAAGCAGG
CCGTGGCCGTGCTGCTGCCCTTCATGGAAGAGGAAAAGCGCCTCAATGGCGGCGAGGGCCGCCAGAGTGC
GGGCAAGGTGCTGATGGCGACCGTCAAGGGCGATGTGCACGATATCGGCAAGAATATCGTGGGCGTGGTT
CTGGCCTGCAATAATTATGAAATCATCGATCTTGGCGTCATGGTGCCCTCGCAGAAAATCCTGCAGGTGG
CGCGCGATGAAAAGGTGGATATCATCGGCCTTTCCGGCCTCATCACGCCTTCGCTTGATGAGATGGCGCA
TGTCGCCGCCGAAATGGAGCGCGAGGGCTTCGATATTCCGCTTTTGATTGGCGGTGCGACGACGAGCCGT
GTTCATACGGCGGTGAAAATCCATTCGCGTTACGAGCGCGGGCAGGCTGTCTATGTCGTGGATGCAAGTC
GTGCGGTGGGGGTCGTGTCAAACCTCCTGTCGCCGGAGGGCAAGCAGGCCTATATCGACGGTTTACGCAA
CGAATATGCCAAGGTGGCTGCTGCCCATGCCCGCAACGAGGCTGAAAAACAGCGCCTGCCAATTGCCCGC
GCGCGCGCCAATCCGCATCAGCTCGACTGGGAAAACTACGAGCCGGTGAAGCCGGCCTTCACCGGAACGA
AGGTTTTTGAAACCTATGATCTGGCGGAAATCGCGCGCTATATCGACTGGACCCCGTTCTTCCAGACCTG
GGAACTGAGGGGCCGCTATCCGGCTATTCTCGAAGATGAAAAGCAGGGTGAGGCGGCGCGCCAGCTCTGG
GCGGATGCGCAAGCGATGCTCCGGAAGATCATCGATGAGAAATGGTTCACCCCGCGGGCGGTGGTCGGCT
TCTGGCCTGCCAATGCGGTGGGCGATGATATCCGCCTCTTTACGGATGAAAGCCGCAAGGAGGAGCTTGC
CACCCTGTTCACGCTTCGCCAGCAGCTTACCAAGCGCGATGGCCGCCCGAATGTCGCCATGGCGGATTTT
GTGGCGCCTGTCGAAAGCGGCAAACAGGATTATGTTGGCGGTTTTGTCGTGACGGCGGGCATTGGCGAGA
TTGCTATCACAGAGCGTTTTGAACGCGCCAATGATGATTATTCCGCCATTCTTGTGAAGGCGCTTGCCGA
TCGTTTCGCGGAAGCCTTCGCGGAACTGATGCATGAGCGTGTGCGCAAGGAATTCTGGGCCTATGCGCCG
GATGAAGCCTTTACGCCGGAAGAACTGATCAGCGAGCCATATAAGGGCATCCGCCCGGCGCCGGGCTATC
CGGCCCAGCCCGATCATACGGAAAAGACCACCTTGTTCCGCCTGCTCGATGCCACCGCCAATACCGGCGT
GGAGCTTACCGAAAGCTACGCCATGTGGCCCGGCTCCTCGGTGTCGGGTCTCTATATCGGTCACCCTGAA
AGCTATTATTTCGGTGTGGCAAAGGTGGAGCGCGATCAGGTCGAGGATTATGCCCGGCGCAAGGACATGG
ATGTGGAGGCTGTGGAGCGCTGGCTCACCCCGATCCTCAATTATGTCCCTGGGGCATCGAAAGACGAAGC
GGCCTG
Protein Sequence 
>gi|23501099|ref|NP_697226.1| B12-dependent methionine synthase [Brucella suis 1330] MASSLDDLFGATAAKPDGSEVLAALTQAARERILILDGAMGTQIQGLGFHEEHFRGDRFATCDCQLQGNNDLLTLTQPKAIEEIHYAYAMAGADILETNTFSSTSIAQADYGMEAMVYDLNRDGARLARRAALRAEQKDGRRRFVAGALGPTNRTASLSPDVNNPGFRAVTFDDLRIAYSEQIRGLIDGGSDIILIETIFDTLNAKAAVFATEEVFAEKGVRLPVMISGTITDLSGRTLSGQTPTAFWYSLRHARPFTIGLNCALGANAMRAHLNELSGIADTFICAYPNAGLPNEFGQYDETPEAMAAQIEGFARDGLVNVVGGCCGSTPDHIRAIAQAVAKYEPRKPAKVPPLMRLSGLEPFTLTKDIPFVNIGERTNVTGSARFRKLVKAGDFAAALDVARDQVANGAQIIDINMDEGLIDSEKAMVEFLNLIAAEPDIARVPIMLDSSKWEVIEAGLKCVQGKAVVNSISLKEGEEAFLHHARLVRAYGAAVVIMAFDETGQADTQARKIEICTRAYKILTEQVGFPPEDIIFDPNIFAVATGIEEHNNYGVDFIEATREIVRTLPHVHISGGVSNLSFSFRGNEPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDTIDAELREACEDVVLNRPTKTGESATERLLEIAERFRDSGSREARTQDLSWREWPVEKRLEHALVNGITEYIEADTEEARLAAERPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPFMEEEKRLNGGEGRQSAGKVLMATVKGDVHDIGKNIVGVVLACNNYEIIDLGVMVPSQKILQVARDEKVDIIGLSGLITPSLDEMAHVAAEMEREGFDIPLLIGGATTSRVHTAVKIHSRYERGQAVYVVDASRAVGVVSNLLSPEGKQAYIDGLRNEYAKVAAAHARNEAEKQRLPIARARANPHQLDWENYEPVKPAFTGTKVFETYDLAEIARYIDWTPFFQTWELRGRYPAILEDEKQGEAARQLWADAQAMLRKIIDEKWFTPRAVVGFWPANAVGDDIRLFTDESRKEELATLFTLRQQLTKRDGRPNVAMADFVAPVESGKQDYVGGFVVTAGIGEIAITERFERANDDYSAILVKALADRFAEAFAELMHERVRKEFWAYAPDEAFTPEELISEPYKGIRPAPGYPAQPDHTEKTTLFRLLDATANTGVELTESYAMWPGSSVSGLYIGHPESYYFGVAKVERDQVEDYARRKDMDVEAVERWLTPILNYVPGASKDEAA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: a.a. metabolism, Synthesis (Delrue et al., 2004).

FUNCTION: Met. synthesis (Delrue et al., 2004).

MUTATION: Attenuated in Mice, Macrophages, HeLa (Delrue et al., 2004).
COG COG1410E, under E: Amino acid transport and metabolism
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].