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cobW from Brucella suis 1330

Victor ID 1016
Gene Name cobW from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1165431
NCBI Protein GI 23500711
Locus Tag BRA0987
Protein Accession NP_700151.1
Other Database IDs UniProtKB-ID: Q8FV62_BRUSU
UniRef100: UniRef100_D0PH58
UniRef90: UniRef90_A6WYN6
UniRef50: UniRef50_A6WYN6
UniParc: UPI00000DDB02
EMBL: AE014292
EMBL-CDS: AAN34156.1
RefSeq_NT: NC_004311.2
HSSP: P24203
GenomeReviews: AE014292_GR
KEGG: bms:BRA0987
NMPDR: fig|204722.1.peg.3060
TIGR: BRA0987
HOGENOM: HBG693975
OMA: ENHGKKY
ProtClustDB: CLSK898791
BioCyc: BSUI204722:BR_A0987-MONOMER
Taxonomy ID 204722
Chromosome No II
Gene Starting Position 973855
Gene Ending Position 974979
Gene Strand (Orientation) +
Protein Name cobalamin synthesis protein/P47K family protein
DNA Sequence 
>gi|56968493:973855-974979 Brucella suis 1330 chromosome II, complete genome
CATGGCCGAAGCCGAGGCAACAGCAACCACTGAAGCTGGCCGCATTCCCGTTACCGTTCTGACCGGATAT
CTGGGCTCGGGGAAAACGACCCTTCTCAATCGCATCCTGACCGAAAACCACGGCAAGCGCTATGCCGTCA
TCGTCAATGAGTTCGGCGAAATCGGCATCGATAACGACCTCATCGTCGAATCGGACGAAGAAATCTACGA
GATGAACAATGGCTGCATCTGCTGCACCGTGCGCGGCGACCTGATCCGCGTGGTGGAAGGCCTGATGCGC
CGCCCCGGACGTTTTGACGCCATTGTGGTGGAGACGACGGGCCTTGCCGATCCGGTTCCGGTTGCGCAGA
CTTTTTTCATGGATGACGACGTGCGCGCCAAGACCGGGCTTGATGCCGTTGTCGCCCTTGTGGATGCCAA
GCACCTGCCGCTGCGCCTGAAGGACAGCCGCGAGGCGGAAGACCAGATCGCATTTGCCGATGTCGTGCTC
ATCAACAAGACCGACCTCGTGACGCCGGAAGAACTGGCGGCGGTCGAAGCCACCGTGCGCGCCATCAACC
CGCACGCAATCATCCACCATACCGAGCGCGCATCGATTCCGCTCAACCGCGTGCTGGACCGTGGCGCCTT
CGACCTGAAGCGCGTTCTGGACAATGATCCGCACTTCCTCGACCATGACGACCCGGACCATGTCTGCGGC
CCCGATTGCGACCACGATCATCATCACCATGGGCATGACCATCACCATCATGATCATCACGATCACGACC
ATGTTTGCGGGCCGGACTGCGACCACGATCACGATCACGATCATGCCTCGCCCATCCACGACGTTACGGT
GAAGTCCGTTTCGCTGCGAACAGGTGAAATTGATCCGGCGAAATTTTTCCCATGGATCCAGAACATTACC
CAGACGCAAGGCCCGAATATCCTACGCCTGAAAGGCATCATCGCCTTCAAGGACGATCCGGACCGCTATG
TCGTGCAGGGCGTGCACATGATTATCGAAGGCGATCACCAGCGCGCGTGGAAGCCGGAAGAAAAGCATGA
AAGCCGCCTCGTCTTCATCGGGCGCGAGCTTGATCCGGCGGCATTGAAAGCCGGTTTTGAGAACTGCCGG
GCCTG
Protein Sequence 
>gi|23500711|ref|NP_700151.1| cobalamin synthesis protein/P47K family protein [Brucella suis 1330] MAEAEATATTEAGRIPVTVLTGYLGSGKTTLLNRILTENHGKRYAVIVNEFGEIGIDNDLIVESDEEIYEMNNGCICCTVRGDLIRVVEGLMRRPGRFDAIVVETTGLADPVPVAQTFFMDDDVRAKTGLDAVVALVDAKHLPLRLKDSREAEDQIAFADVVLINKTDLVTPEELAAVEATVRAINPHAIIHHTERASIPLNRVLDRGAFDLKRVLDNDPHFLDHDDPDHVCGPDCDHDHHHHGHDHHHHDHHDHDHVCGPDCDHDHDHDHASPIHDVTVKSVSLRTGEIDPAKFFPWIQNITQTQGPNILRLKGIIAFKDDPDRYVVQGVHMIIEGDHQRAWKPEEKHESRLVFIGRELDPAALKAGFENCRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis cobW gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0523R, under R: General function prediction only
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].