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gcvT from Brucella suis 1330

Victor ID 1006
Gene Name gcvT from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1165169
NCBI Protein GI 23500464
Locus Tag BRA0727
Protein Accession NP_699904.1
Other Database IDs UniProtKB-ID: Q8FVU8_BRUSU
UniRef100: UniRef100_A9MC13
UniRef90: UniRef90_A9MC13
UniRef50: UniRef50_A1UTQ5
UniParc: UPI00000DDA33
EMBL: AE014292
EMBL-CDS: AAN33909.1
RefSeq_NT: NC_004311.2
GenomeReviews: AE014292_GR
KEGG: bms:BRA0727
NMPDR: fig|204722.1.peg.2813
TIGR: BRA0727
HOGENOM: HBG299834
OMA: FGAFAGW
ProtClustDB: PRK13579
BioCyc: BSUI204722:BR_A0727-MONOMER
Taxonomy ID 204722
Chromosome No II
Gene Starting Position 712067
Gene Ending Position 713170
Gene Strand (Orientation) -
Protein Name glycine cleavage system T protein
DNA Sequence 
>gi|56968493:712067-713170 Brucella suis 1330 chromosome II, complete genome
ATCATCCTTTGCGATAGCGATGCGGTGTGAAGGGAAGTGCGTGGACGTCAACGGGAACCTTGTTGCCGCG
AACATCTGCAAAAACACGGGTGCCGGGGGTGGCGAGGCTTGCCTCGACATAGCCCATGGCGACCGGGAAA
CCGGCGGAAGGGCCAAAGCCGCCCGAGGTGACGGTGCCGATCTGGCGGCCACTTTCGTCGAAAAGGTCGG
CCCCGGCGCGCACCGGCTGGCGGCCTTCCGGCTTGAGGCCGACGCGCTTGGCGCTGGCGCCTTTGGCAAT
GGCGTCAAGAACGGCTTTCGCGCCGTTGAAGGCGGCTTTTTCGCGCACAGCCTTGGTGATCGCCCAGGTG
AGGCCAGCCGAAACCGGATCGGTTTCCGGCGTGATGTCCTGACCGTGCAGGCAGAGGCCCGCTTCGAGGC
GTAAGGAATCGCGGGCGGCAAGGCCGATCCATTCGACACGTTCATCGGCAAGAAGCTTTTCGGCCAGCGC
ACGGGCTTCATCGGCAGGCAGGCCAATCTCGAAACCGTCTTCGCCGGTATAGCCCGAACGGGTCATGAAC
CAGCCCTGTTTCGGCTCGAAACCGCTCATGAAGGCAAGATCGGCGCCCGGCAGACCGGCATCGGTGATGA
CAGCTTCTGCTTCCGGCCCCTGCAAAGCAAGGAAAACACGGTCGAGCGGATTAACCTTTACGGCCTTGCC
CGACGCGGCTTCATTGAGATGCTCGATGTCGGCATCGGCATTGCCCGCATTGGCAACAACCATGAAACGG
TCTTCGCCAAGGCGCGTGACGATGAGATCATCCAGCACGCCGCCATTATCATTGAGGAAGAACGTATATT
TCGACTGGCCCGTCTTCAGGATCGTCGGATCGAGCGGGCAGGTCTCGGCGAGAAGCGCGGCGGCATCCGC
GCCGGAAACTTCCACCAGCTTCATGTGGGAAATGTCGAAGAGGCCCGCATGGTCGCGCGTATGAAGATGT
TCCTTCATCACACCCAGCGGATAGGTGATTGGCATGTTCCAGCCGGCAAAGCCGCCGAAGCGCGCGCCAG
CCTTTTCATGCAGATCCTGCAACGGCAGGGTATTCAAATGTGCGGTATCGCCCA
Protein Sequence 
>gi|23500464|ref|NP_699904.1| glycine cleavage system aminomethyltransferase T [Brucella suis 1330] MGDTAHLNTLPLQDLHEKAGARFGGFAGWNMPITYPLGVMKEHLHTRDHAGLFDISHMKLVEVSGADAAALLAETCPLDPTILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVVANAGNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVITDAGLPGADLAFMSGFEPKQGWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAGLCLHGQDITPETDPVSAGLTWAITKAVREKAAFNGAKAVLDAIAKGASAKRVGLKPEGRQPVRAGADLFDESGRQIGTVTSGGFGPSAGFPVAMGYVEASLATPGTRVFADVRGNKVPVDVHALPFTPHRYRKG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A study with miniTn5 mutants of B. suis constitutively expressing gfp indicates that B. suis gcvT gene is required for intracellular multiplication in human macrophage THP-1 cells (Kohler et al., 2002).
COG COG0404E, under E: Amino acid transport and metabolism
References
Kohler et al., 2002: Kohler S, Foulongne V, Ouahrani-Bettache S, Bourg G, Teyssier J, Ramuz M, Liautard JP. The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell. Proceedings of the National Academy of Sciences of the United States of America. 2002 Nov 26; 99(24); 15711-6. [PubMed: 12438693 ].