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Rv3616c

Victor ID 100
Gene Name Rv3616c
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885377
NCBI Protein GI 15610752
Locus Tag Rv3616c
Protein Accession NP_218133.1
Other Database IDs UniProtKB-ID: ESPA_MYCTU
UniRef100: UniRef100_O06267
UniRef90: UniRef90_O06267
UniRef50: UniRef50_O06267
UniParc: UPI00000CCAFA
EMBL: BX842583
EMBL: AE000516
EMBL-CDS: CAB08950.1
EMBL-CDS: AAK48077.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000000738
EnsemblGenome_TRS: EBMYCT00000000738
EnsemblGenome_PRO: EBMYCP00000000738
GenomeReviews: AE000516_GR
GenomeReviews: AL123456_GR
KEGG: mtu:Rv3616c
TIGR: MT3718
TubercuList: Rv3616c
HOGENOM: HBG569597
OMA: SAINGLH
ProtClust
Taxonomy ID 83332
Gene Starting Position 4055196
Gene Ending Position 4056374
Gene Strand (Orientation) -
Protein Name CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN
DNA Sequence 
>gi|57116681:4055196-4056374 Mycobacterium tuberculosis H37Rv, complete genome
GTTAGACGACGTTTCGTACCAGCACCTTTTGCCCACCGCCCGCGTCAGCTTCGACTGGCGCGCGCTCGGC
GTCTTCAGTGCCCGCCGCCGCGCCTTCCGAGTACTTCTTCGTCGTCGTCCCTTTCGACGCCCCCGAAGAG
GGGTGCATGCCGCCCATGCCTACGGGTCCGCCCATACCTTGGGAACCCTGCGCGGAGACCAGCTGCGACT
GCCCGCCGACCTGCTCGGCAGCGGCGCCGACCGGGCCATCAGCTCGGGGCCGTAGCGCCTGCCGAGTTGA
GGCGGCATGGACCTGAGCCAGGCTCGGCAAGCCCCCAAAACCGGACCCGCCCCCAATGCCGGCCAGGGCG
GGCAAGCTGGCTGAGCTCGCCAGGCTATCCGCGTGAGCCAAGCCCGACGATGCGGACAGACCGGCCGCAC
CGAACAAGCCAGTCACTTGCGACAAGCCGCTGGTCGCGCCGGTCAAGCCGGGGACGCCCGCAAAGAAGGA
CTCCAGGTTCGACCACCCTCGAGAGAACAGTCCGGTCACCCACCCCGTGAGCTTGTCCCAAAGCTCTTTC
AGGCCGTTGAGCGCGTTTGTGATGAACTCCCACACTTCTCCGAGGGTGCCCTTGATGATGTCCGCCACAT
CCGAAATGATGTCCGCAATGGCGGCCGCGACCAACTCCGCCAATTTGGCAAGCAATTTGAGGAGTTGAGT
CGCGTTGATCAGCGTTTTCACGACCAAGTAGGCAAGCGCGCCGCCCACTACGGCCATCGCGCCCGCGCAA
AACGGCGCCTGGAAGGCGGCCGATAGGGCGTGCCCGACGACCGGGATGTAGGTCAGGTCCACAGCCACCG
GGCGCACGAACTCGAGACCTTTCTTGGCGCCCTCCAGGATGTCGCGGGTCGTCTGGACCGCGTTGGCCTG
GTCGTGGATCAGGCTGATGAGCTGACGATCGAGGTCTGCCAGTTCCTGGAAAAAATTCACGTGGTTGCGG
TTTTTGCCGGCGTATTTGTCCGCGGCCGAACCTAACCAGCCATCACCCGGAAACGCTGCTGCCAGCTCCT
CCAGGGCTTTTTCGAAGTACTCTAGTGAGGAGTAAAGGATACCCCCTTGGTTGGGTATTCCAATCCCCAG
AAGGTCGTACAAGCCGTCAATGGCACTGATCGTTGGATCGATGATGAACGCTCTGCTCA
Protein Sequence 
>gi|15610752|ref|NP_218133.1| ESX-1 secretion-associated protein EspA [Mycobacterium tuberculosis H37Rv] MSRAFIIDPTISAIDGLYDLLGIGIPNQGGILYSSLEYFEKALEELAAAFPGDGWLGSAADKYAGKNRNHVNFFQELADLDRQLISLIHDQANAVQTTRDILEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGALAYLVVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGTLGEVWEFITNALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATSGLSQVTGLFGAAGLSASSGLAHADSLASSASLPALAGIGGGSGFGGLPSLAQVHAASTRQALRPRADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMGGMHPSSGASKGTTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3616c mutant is attenuated in mice (Fortune et al., 2005).
References
Fortune et al., 2005: Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ. Mutually dependent secretion of proteins required for mycobacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(30); 10676-10681. [PubMed: 16030141].